Accession_ID Standard Name Systematic Name Synonym Full Name Organism Common Name Genus Species Description Comment DataSource DataSource_Key
588 EB1 microtubule-associated protein Dictyostelium DDB DDB0191160
2895 PLIP phosphatidylinositol phosphatase Dictyostelium DDB DDB0185057
2917 abcB1 mrpA ABC transporter B family protein Dictyostelium DDB DDB0201666
2920 abcB4 ABC transporter B family protein Dictyostelium DDB DDB0208540
2921 abcB5 ABC transporter B family protein Dictyostelium DDB DDB0201625
2970 abpA actin binding protein,actin bundling protein,alpha actinin Dictyostelium DDB DDB0191133
2972 abpD actin binding protein,interaptin Dictyostelium DDB DDB0191136
2985 act15 act3a;actin15;actinA1;actinIII-12;actinIII-12/A1 actin Dictyostelium DDB DDB0185015
2987 act2 act2-1;actin2;actin2-sub1 actin Dictyostelium DDB DDB0185124
2988 act17 act2-2;actin2;actin2sub-2;actin2sub2 actin Dictyostelium DDB DDB0185125
2993 act6 actin6 actin Dictyostelium DDB DDB0185126
2999 act16 actinM6 actin Dictyostelium DDB DDB0185127
3020 apm2 AP2M2;DdApm1 AP-2 medium chain,AP-2 µ2,clathrin-adaptor medium chain Dictyostelium DDB DDB0191267
3058 cbpA CBP1 calcium-binding protein Dictyostelium DDB DDB0185026
3100 culA cullin Dictyostelium DDB DDB0185191
3114 dagA CRAC;synag7 PH domain-containing protein,cytosolic regulator of adenylate cyclase,cytosolic regulator of adenylyl cyclase Dictyostelium DDB DDB0191434
3147 fbxA chtA F-Box A protein,cheaterA Dictyostelium DDB DDB0185042
3171 gmsA gamete and mating-type specific protein A Dictyostelium DDB DDB0191145
3173 gpaA Ga1;Galpha1;gpa1 G-protein subunit alpha 1 Dictyostelium DDB DDB0191255
3174 gpaB Ga2;Galpha2;gpa2 G-protein subunit alpha 2 Dictyostelium DDB DDB0191327
3193 hspC hsp32 heat shock protein Dictyostelium DDB DDB0185048
3234 mlcE EMLC essential myosin light chain (ELC) Dictyostelium DDB DDB0214813
3259 ndkC gip17;NDK NDP kinase,nucleoside diphosphate kinase Dictyostelium DDB DDB0185051
3260 ndkM NDK NDP kinase,nucleoside diphosphate kinase Dictyostelium DDB DDB0214817
3315 pspA D19;psA;SP29 cell surface glycoprotein PsA precursor Dictyostelium DDB DDB0191129
3383 sadA substrate adhesion molecule Dictyostelium DDB DDB0191090
3406 spnA Spalten;Spn protein serine/threonine phosphatase Dictyostelium DDB DDB0185064
3460 α-Adaptin &agr;;&agr; adaptin;&agr;-Ada;&agr;-Adaptin;ada;alpha;alpha adaptin;alpha-Ada;alpha-adaptin;AP-2;AP2;CG11994;CG31654;cg4260;CG7807;D-&agr;Ada;D-Ada;D-alphaAda;dADA;dAP-2;dAP-2&agr;;dAP-2a;DrosADA;l(2)06694;stummelbein α-Adaptin fruit fly Drosophila melanogaster The D. melanogaster gene α-Adaptin is reported here. It has also been known in FlyBase as l(2)06694. It encodes a product involved in neurotransmitter secretion which is a component of the AP-2 adaptor complex. It has been sequenced and its amino acid sequence contains an alpha adaptin carboxyl-terminal domain. It has been mapped cytologically to 21C6. It interacts genetically with slbo, Chc and lqf. There are 10 recorded alleles: 9 classical mutants (1 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the synapse and are larval recessive lethal, conditional ts locomotor behavior defective, conditional ts uncoordinated, neurophysiology defective, neuroanatomy defective and conditional ts (with α-Adaptin4) visible. α-Adaptin is discussed in 55 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 4 studies of mutant phenotypes and 4 molecular studies. FB FBgn0015567
3461 α-Cat &agr;-CAT;&agr;-catenin;&agr;-ctn;&agr;cat;a-cat;alpha-Cat;alpha-catenin;alpha-ctn;alphacat;catenin;CG17947;CT39986;D&agr;-cadherin;D&agr;-cat;D&agr;-catenin;D&agr;C;D&agr;Catenin;D-&agr;-catenin;D-alpha-catenin;Dalpha-cadherin;Dalpha-cat;Dalpha-catenin;DalphaC;DalphaCatenin;Dmcatp α Catenin fruit fly Drosophila melanogaster The D. melanogaster gene α Catenin, abbreviated as α-Cat, is reported here. It encodes a product with cadherin binding involved in oocyte positioning which is a component of the spot adherens junction. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 80E2--3. There are 6 recorded alleles: 5 in vitro constructs (none available from the public stock centers) and 1 wild-type. α-Cat is discussed in 96 references (excluding sequence accessions), dated between 1993 and 2003. These include at least one study of wild-type function and one molecular study. FB FBgn0010215
3462 α-Est1 &agr;-Est1;&agr;E1;A;aE1;alphaE1;Arc;bran;broad angular;CG1031;CG13505;CG6741;fragment A α-Esterase-1 fruit fly Drosophila melanogaster The D. melanogaster gene α-Esterase-1, abbreviated as α-Est1, is reported here. It encodes a product with carboxylesterase activity (EC:3.1.1.1). It has been sequenced and its amino acid sequence contains an esterase/lipase/thioesterase family active site and a carboxylesterases type-B. It has been mapped cytologically to 84D9. There is one recorded allele, which is wild-type. α-Est1 is discussed in 8 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 3 molecular studies. FB FBgn0015568
3476 α-Man-I &agr;-D-mannosidase;&agr;-Man-I;&agr;-mannosidase;2 mannosidase;alpha 1;alpha 1,2 mannosidase;alpha Mannosidase I;alpha-D-mannosidase;alpha-Man-I;alpha-Man-l;alpha-mannosidase;CG17809;CG18799;CG32684;DM-GI;MA12;Man'ase;MAN-1;mas-1 α Mannosidase I fruit fly Drosophila melanogaster The D. melanogaster gene α Mannosidase I, abbreviated as α-Man-I, is reported here. It has also been known in FlyBase as CG18799. It encodes a product with mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (EC:3.2.1.113) involved in N-linked glycosylation which is a component of the Golgi membrane. It has been sequenced and its amino acid sequence contains a glycosyl hydrolase family 47. It has been mapped by recombination to 1-30.1 and cytologically to 9B5--7. There are 13 recorded alleles: 12 classical mutants (4 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the ommatidium, the interommatidial bristle and the peripheral nervous system. α-Man-I is discussed in 22 references (excluding sequence accessions), dated between 1992 and 2003. These include at least one study of mutant phenotypes and 2 molecular studies. FB FBgn0010338
3477 α-Man-II &agr;-Man-II;&agr;-mannosidase 2;alpha-Man-II;alpha-mannosidase 2;alpha-mannosidase II;CG18474;CG18802;CG8139;dGMII;DM-GII.1;GMII;Golgi Man II;Golgi mannosidase II;MAN-2;mannosidase II α Mannosidase II fruit fly Drosophila melanogaster The D. melanogaster gene α Mannosidase II, abbreviated as α-Man-II, is reported here. It has also been known in FlyBase as CG18474. It encodes a product with mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity (EC:3.2.1.114) involved in N-linked glycosylation which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence contains a glycosyl hydrolases family 38. It has been mapped cytologically to 85D15--16. There are 5 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. α-Man-II is discussed in 26 references (excluding sequence accessions), dated between 1992 and 2003. These include at least one study of mutant phenotypes and 2 molecular studies. FB FBgn0011740
3478 α-Man-IIb &agr;-D-mannosidase;&agr;-Man-IIb;&agr;-mannosidase;&agr;-mannosidase 2;alpha-D-mannosidase;alpha-M-II;alpha-mannosidase;alpha-mannosidase 2;CG4606;DM-GII.2;GTD#24/1;Man'ase;mannosidase II fruit fly Drosophila melanogaster The D. melanogaster gene α-Man-IIb is reported here. It encodes a product with alpha-mannosidase activity (EC:3.2.1.24) putatively involved in carbohydrate metabolism which is a component of the Golgi apparatus. It has been sequenced and its amino acid sequence contains a glycosyl hydrolases family 38. It has been mapped cytologically to 89A5. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. α-Man-IIb is discussed in 14 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0026616
3479 α-Spec ;&agr;;&agr; spectrin;&agr;-Spc;&agr;-Spec;&agr;-Spectrin;3A9;alpha;alpha spectrin;alpha-Spc;alpha-Spec;alpha-spectrin;alpha-spectrin II;anon-EST:fe2E2;anon-fast-evolving-2E2;CG1977;dre3;l(3)&agr;-Spec;l(3)04276;l(3)62Bd;l(3)alpha-Spec;l(3)dre3;spectrin α Spectrin fruit fly Drosophila melanogaster The D. melanogaster gene α Spectrin, abbreviated as α-Spec, is reported here. It has also been known in FlyBase as anon-EST:fe2E2 and anon-fe2E2. It encodes a product with actin binding involved in oocyte construction which is a component of the spectrosome. It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 62B4. There are 24 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 15 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the cuprophilic cell, the midgut interstitial cell, the germ-line clone germline cyst and 9 other listed tissues and are larval recessive lethal, somatic clone female sterile, somatic clone mitotic, recessive hypoactive and neurophysiology defective. α-Spec is discussed in 191 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 2 studies of mutant phenotypes, 5 studies of wild-type function and 8 molecular studies. Among findings on α-Spec function, α-Spec is required for ovarian follicle monolayer integrity. FB FBgn0003470
3480 αCop &agr;-COP;&agr;Cop;alpha-COP;alphaCop;CG7961 α-coatomer protein fruit fly Drosophila melanogaster The D. melanogaster gene α-coatomer protein, abbreviated as αCop, is reported here. It encodes a product involved in retrograde transport, Golgi to ER which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 62A12. There is one recorded allele, which is wild-type. αCop is discussed in 7 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 2 molecular studies. FB FBgn0025725
3481 αPS4 &agr;-ps4;&agr;PS4;alphaPS4;CG16827;CT37393 fruit fly Drosophila melanogaster The D. melanogaster gene αPS4 is reported here. It has also been known in FlyBase as CG16827. It encodes a product with receptor activity involved in heterophilic cell adhesion which is a component of the integrin complex. It has been sequenced and its amino acid sequence contains an integrins α chain. It has been mapped cytologically to 51E11. There is one recorded allele, which is wild-type. αPS4 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034005
3482 αPS5 &agr;PS5;alphaPS5;CG5372;CT17068 fruit fly Drosophila melanogaster The D. melanogaster gene αPS5 is reported here. It has also been known in FlyBase as CG5372. It encodes a product with receptor activity involved in heterophilic cell adhesion which is a component of the integrin complex. It has been sequenced and its amino acid sequence contains an integrins α chain. It has been mapped cytologically to 59E4. There is one recorded allele, which is wild-type. αPS5 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034880
3484 αTub67C &agr; tubulin;&agr;-Tub;&agr;-Tub67C;&agr;-Tubulin;&agr;4;&agr;4-t;&agr;4-tubulin;&agr;4t;&agr;67C;&agr;TUB;&agr;Tub4;&agr;tub67C;&agr;Tub67C;&agr;tubulin;&mgr;m-tub67C;4t;ALPHA 6;ALPHA 67C;alpha tubulin;alpha tubulin 67C;alpha-tubulin;alpha4;alpha4-t;alpha4-tubulin;alpha4Tub67C;alpha67C;alphaTub67C;alphatubulin;alphaTub[67C];anon-EST:fe1F6;anon-fast-evolving-1F6;aTub67C;barbu;Bbu;bbu/tom;CG5185;CG8308;D.m.ALPHA-67C;DTA2;Fs(3)Sz22;Fs(3)Tom;Fs(3)Tomaj;T;Tom;Tomaj;tubulin α-Tubulin at 67C fruit fly Drosophila melanogaster The D. melanogaster gene α-Tubulin at 67C, abbreviated as αTub67C, is reported here. It encodes a product with GTP binding involved in female pronucleus formation which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-32.26 and cytologically to 67C4. It interacts genetically with αTub84B, αTub84D, ncd and nod. There are 25 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 21 classical mutants (3 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the female pronucleus and are recessive female sterile, (with αTub67C1 to 2) female sterile and dominant meiotic. αTub67C is discussed in 106 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 6 studies of mutant phenotypes, 3 studies of wild-type function and one molecular study. Among findings on αTub67C mutants, mutations in αTub67C specifically impair achiasmate segregation. Among findings on αTub67C function, the αTub67C gene product is involved in the formation of the sperm aster, cleavage spindle apparatus formation or function and the differentiation of the embryonic nervous system. FB FBgn0004236
3485 αTub84B ;&agr; tubulin;&agr;-Tub;&agr;-Tub84B;&agr;-Tubulin;&agr;1;&agr;1 tubulin;&agr;1-tubulin;&agr;1t;&agr;1tub;&agr;84B;&agr;T;&agr;t-1;&agr;Tub;&agr;Tub1;&agr;Tub84B;&agr;tubulin;1t;a1t;ALPHA 84C;alpha tubulin;alpha-tubulin;alpha1;alpha1 tubulin;alpha1-tubulin;alpha1t;alpha84B;alphaT;alphat-1;alphaTub;alphaTub84B;alphatubulin;anon-EST:Liang-1.59;anon-EST:Liang-2.30;aTub84B;BEST:LD32507;CG1913;clone 1.59;clone 2.30;DM1&agr;;DTA1;l(3)84Bd;l(3)g3;ms(3)nc33;nc33;T;T&agr;1;Talpha1;Tub&agr;1;tubA84B;Tubalpha1;tubulin;tubulin &agr;1;Tubulin 1 &agr;-chain;tubulin 1&agr;;Tubulin-&agr;1;Tubulin-alpha1 α-Tubulin at 84B fruit fly Drosophila melanogaster The D. melanogaster gene α-Tubulin at 84B, abbreviated as αTub84B, is reported here. It encodes a product with GTP binding putatively involved in cell motility which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-47.7 and cytologically to 84B4. It interacts genetically with βTub85D, αTub67C and αTub84D. There are 30 recorded alleles: 21 in vitro constructs (1 available from the public stock centers), 8 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which are lethal. αTub84B is discussed in 145 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 4 studies of mutant phenotypes, 6 studies of wild-type function and 2 molecular studies. Among findings on αTub84B function, αTub84B staining is used to analyze microtubule configuration during the first division of the zygote to investigate the organization of the first cleavage spindle and the origin of the functional centrosome. FB FBgn0003884
3486 αTub84D &agr; tubulin;&agr;-Tub;&agr;-Tub84D;&agr;-Tubulin;&agr;3;&agr;3t;&agr;84D;&agr;TUB;&agr;Tub3;&agr;Tub84D;&agr;tubulin;3t;ALPHA 84D;alpha tubulin;alpha-Tub;alpha-Tub84D;alpha-tubulin;alpha3;alpha3t;alpha84D;alphaTUB;alphaTub3;alphaTub84D;alphatubulin;aTub84D;CG2512;D.m.ALPHA-84D;DTA4;T;tubulin;tubulin &agr;3;tubulin alpha3 α-Tubulin at 84D fruit fly Drosophila melanogaster The D. melanogaster gene α-Tubulin at 84D, abbreviated as αTub84D, is reported here. It encodes a product with GTP binding putatively involved in microtubule-based process which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 84D9. It interacts genetically with αTub67C and αTub84B. There is one recorded allele, which is wild-type. αTub84D is discussed in 86 references (excluding sequence accessions), dated between 1980 and 2003. These include at least one study of wild-type function and 2 molecular studies. FB FBgn0003885
3487 αTub85E &agr; tubulin;&agr;-Tub85E;&agr;-Tubulin;&agr;2;&agr;2-tubulin;&agr;2t;&agr;2tubulin;&agr;85E;&agr;85E-tubulin;&agr;Tub2;&agr;Tub84E;&agr;Tub85E;&agr;tubulin;2t;a2t;ALPHA 85E;alpha tubulin;alpha-Tub85E;alpha-tubulin;alpha2;alpha2-tubulin;alpha2t;alpha2tubulin;alpha85E;alpha85E-tubulin;alphaTub2;alphaTub84E;alphatubulin;aTub85E;CG9476;DTA3;T α-Tubulin at 85E fruit fly Drosophila melanogaster The D. melanogaster gene α-Tubulin at 85E, abbreviated as αTub85E, is reported here. It encodes a product with GTP binding putatively involved in cell motility which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 85E6. There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. αTub85E is discussed in 73 references (excluding sequence accessions), dated between 1980 and 2003. These include at least one study of mutant phenotypes, 2 studies of wild-type function and 2 molecular studies. FB FBgn0003886
3488 β'Cop &bgr;'Cop;beta'-COP;beta'Cop;CG6699;d&bgr;'COP;dbeta'COP β'-coatomer protein fruit fly Drosophila melanogaster The D. melanogaster gene β'-coatomer protein, abbreviated as β'Cop, is reported here. It encodes a product involved in Golgi vesicle budding which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 34B9. There is one recorded allele, which is wild-type. β'Cop is discussed in 9 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 2 molecular studies. FB FBgn0025724
3490 β-Spec &bgr;;&bgr; spectrin;&bgr;-Spec;&bgr;-spectrin;&bgr;Spec;anon-EST:fe1B3;anon-fast-evol;anon-fast-evolving-1B3;b-Spec;beta;beta spectrin;beta-Spec;beta-spectrin;betaSpec;CG5870;i168;i6;l(1)G0074;l(1)G0108;l(1)G0198;Spec&bgr;;Spec-&bgr;;Spec-beta;SPEC8;Specbeta;spectrin β Spectrin fruit fly Drosophila melanogaster The D. melanogaster gene β Spectrin, abbreviated as β-Spec, is reported here. It has also been known in FlyBase as anon-EST:fe1B3, anon-fe1B3, l(1)G0074, l(1)G0108 and l(1)G0198. It encodes a product with actin cross-linking activity involved in fusome organization and biogenesis which is a component of the spectrosome. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 16B10--12. There are 14 recorded alleles: 1 in vitro construct (not available from the public stock centers), 12 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic larval midgut and are embryonic recessive lethal. β-Spec is discussed in 92 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 4 studies of mutant phenotypes, 3 studies of wild-type function and 3 molecular studies. Among findings on β-Spec function, the distribution of β-Spec product suggests roles in establishing an apicolateral membrane domain that is known to be rich in intercellular junctions and in establishing a unique membrane domain associated with contractile processes. FB FBgn0003471
3494 βCop &bgr;-COP;&bgr;-CopII;&bgr;Cop;BcDNA.GH09317;BcDNA:GH09317;bcop;beta-COP;beta-CopII;BetaCop;CG6223 β-coatomer protein fruit fly Drosophila melanogaster The D. melanogaster gene β-coatomer protein, abbreviated as βCop, is reported here. It has also been known in FlyBase as β'Cop. It encodes a product involved in retrograde transport, Golgi to ER which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 17A9. There are 5 recorded alleles: 4 in vitro constructs (none available from the public stock centers) and 1 wild-type. βCop is discussed in 18 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of wild-type function and one molecular study. FB FBgn0008635
3497 βInt-nu &bgr;&ngr;;&Bgr;&ngr;;&bgr;v;&bgr;&ngr;-intergin;&bgr;Int-&ngr;;&bgr;Int&ngr;;&bgr;v;betaInt[nu];betanu;betav;Beta[[nu]];beta[[v]];CG1762;CT5192;integrin &bgr; v;integrin beta neu;Integrin bn β[nu] integrin fruit fly Drosophila melanogaster The D. melanogaster gene β&ngr; integrin, abbreviated as βInt-&ngr;, is reported here. It has also been known in FlyBase as βInt and βInt&ngr;. It encodes a product with receptor activity involved in cell-matrix adhesion which is a component of the integrin complex. It has been sequenced and its amino acid sequence contains an integrins, β chain and a PSI domain. It has been mapped cytologically to 39A1. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. βInt-&ngr; is discussed in 18 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 2 studies of mutant phenotypes and one molecular study. Among findings on βInt-&ngr; mutants, embryos transheterozygous for deficiencies that remove βInt-&ngr; develop a normal midgut. FB FBgn0010395
3499 βTub56D ;&bgr; tubulin;&bgr;-1-tubulin;&bgr;-tub;&bgr;-Tub56D;&bgr;-tubulin;&bgr;1;&bgr;1 tubulin;&bgr;1-tubulin;&bgr;1t;&bgr;1tub;&bgr;56D;&bgr;1 tubulin;&bgr;1-tubulin;&bgr;Tub1;&bgr;Tub56D;&bgr;tubulin;1t;B1t;BETA 56D;beta tubulin;beta-1 tubulin;beta-1-tubulin;beta-tubulin;beta1;beta1 tubulin;beta1-tubulin;beta1t: beta1 tubulin;beta1Tub;beta56D;betaTub56D;beta[[1]] tubulin;beta[[1]]-tubulin;CG9277;Dm&bgr;1;Dmbeta1;DTB2;T;Tubulin β-Tubulin at 56D fruit fly Drosophila melanogaster The D. melanogaster gene β-Tubulin at 56D, abbreviated as βTub56D, is reported here. It encodes a product with structural constituent of cytoskeleton involved in muscle attachment which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 56D7--8. There are 7 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. βTub56D is discussed in 106 references (excluding sequence accessions), dated between 1982 and 2003. These include at least 10 studies of mutant phenotypes and one molecular study. FB FBgn0003887
3500 βTub60D &bgr; tubulin;&bgr; Tubulin4;&bgr;-3tubulin;&bgr;-tub;&bgr;-Tub60D;&bgr;-Tub6D;&bgr;-tubulin;&bgr;3;&bgr;3 TU;&bgr;3 tubulin;&bgr;3-Tub;&bgr;3-tubulin;&bgr;3t;&bgr;3tubulin;&bgr;60C;&bgr;3 tubulin;&bgr;3-Tub;&bgr;3-tubulin;&bgr;Tub3;&bgr;Tub60C;&bgr;Tub60D;3t;60C &bgr; tubulin;60C beta tubulin;B3-tubulin;B3t;beta 3 tubulin;BETA 60D;Beta tubulin;beta-3 Tubulin;beta-3tubulin;beta-tub;beta-tubulin;beta3;beta3 tubulin;beta3-tubulin;beta3t: beta3 tubulin;beta60C;betaTub60C;betaTub60D;beta[;beta[[3]] tubulin;beta[[3]]-tubulin;CG3401;D.m.BETA-60D;Dm&bgr;3;Dmbeta3;DTB3;p50;p50/tubulin;p53;p53/tubulin;T;tubulin;tubulin b-3 β-Tubulin at 60D fruit fly Drosophila melanogaster The D. melanogaster gene β-Tubulin at 60D, abbreviated as βTub60D, is reported here. It encodes a product with GTP binding involved in axonogenesis which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60C6. There are 21 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 14 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the embryonic larval midgut and are recessive lethal, recessive phototaxis behavior defective and (with Df(2R)Px2) phototaxis behavior defective. βTub60D is discussed in 119 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 2 studies of mutant phenotypes, 3 studies of wild-type function and 10 molecular studies. Among findings on βTub60D function, the expression of βTub60D in several embryonic sense organs makes sense of the behavioral defects of pre-lethal βTub60D mutant larvae. FB FBgn0003888
3501 βTub85D &bgr; tubulin;&bgr;(2)Tu;&bgr;-tub;&bgr;-Tub85D;&bgr;-tubulin;&bgr;2;&bgr;2 tubulin;&bgr;2-tubulin;&bgr;2t;&bgr;2tub;&bgr;2tubulin;&bgr;85D;&bgr;2-tubulin;&bgr;Tub2;&bgr;Tub85D;2t;b2 tubulin;B2t;BETA 85D;beta tubulin;beta(2)Tu;beta-Tu;beta-tubulin;BETA2;beta2 tubulin;beta2-tubulin;beta2t;beta2tub;beta2tubulin;beta85D;betaTub85D;beta[[2]]-tubulin;CG9359;D.m.BETA-85D;Dm&bgr;2;Dmbeta2;DTB4;ms(3)KKD;testis-specific &bgr;-tubulin;tubulin β-Tubulin at 85D fruit fly Drosophila melanogaster The D. melanogaster gene β-Tubulin at 85D, abbreviated as βTub85D, is reported here. It encodes a product with GTP binding putatively involved in microtubule-based process which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-48.5 and cytologically to 85D15. It interacts genetically with αTub84B, wrl, hay, mrn, ms(3)nc3 and 3 other listed genes. There are 19 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 14 classical mutants (6 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the microtubule, the testis, the spermatid axoneme and 2 other listed tissues and are recessive male sterile, (with βTub85Dn) male sterile and (with βTub85D8) male fertile. βTub85D is discussed in 95 references (excluding sequence accessions), dated between 1979 and 2003. These include at least 16 studies of mutant phenotypes, one study of wild-type function and 2 molecular studies. FB FBgn0003889
3502 βTub97EF &bgr; tubulin;&bgr; Tubulin3;&bgr;-tub;&bgr;-Tub97EF;&bgr;-tubulin;&bgr;4 tubulin;&Bgr;4-tubulin;&bgr;4t;&bgr;97F;&bgr;Tub4;&bgr;Tub97EF;&bgr;Tub98BC;&bgr;Tub98C;&bgr;tubulin;4t;B4t;BETA 98B;beta tubulin;beta-Tub97EF;beta-tubulin;beta4 tubulin;Beta4-tubulin;beta4t: beta4 tubulin;beta97F;betaTub4;betaTub98BC;betaTub98C;betatubulin;CG4869;Dm&bgr;4;Dmbeta4;DTB1;T;tubulin β-Tubulin at 97EF fruit fly Drosophila melanogaster The D. melanogaster gene β-Tubulin at 97EF, abbreviated as βTub97EF, is reported here. It has also been known in FlyBase as CG4869. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cell motility which is putatively a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98B6--7. There is one recorded allele, which is wild-type. βTub97EF is discussed in 50 references (excluding sequence accessions), dated between 1982 and 2003. These include at least one molecular study. FB FBgn0003890
3503 δ-catenin &dgr;-catenin;catenin;d-catenin;P120 fruit fly Drosophila melanogaster The D. melanogaster gene δ-catenin is reported here. It encodes a product which is a component of the zonula adherens. There is one recorded allele, which is wild-type. δ-catenin is discussed in 3 references, dated between 2000 and 2003. FB FBgn0041583
3504 δCOP &dgr;-Cop;&dgr;COP;63B12S;anon-WO03040301.246;Arch;Archain;ARCN1;CG14813;coatomer complex COPI delta-COP subunit;delta-coatomer protein;delta-Cop;DeltaCop;DM63B12S;EG:63B12.10;ESTS:63B12S;l(1)G0051;l(1)G0301;l(1)G0450 δ-coatomer protein fruit fly Drosophila melanogaster The D. melanogaster gene δ-coatomer protein, abbreviated as δCOP, is reported here. It has also been known in FlyBase as Arch, CG14813, EG:63B12.10, ESTS63B12S, l(1)G0051, l(1)G0301 and l(1)G0450. It encodes a product involved in retrograde transport, Golgi to ER which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2B12--13. There are 6 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. δCOP is discussed in 21 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 molecular studies. FB FBgn0028969
3508 γCop &ggr;-COP;&ggr;Cop;anon-WO0118547.334;CG1528;copg;gamma-coatomer protein;gammaCop γ-coatomer protein fruit fly Drosophila melanogaster The D. melanogaster gene γ-coatomer protein, abbreviated as γCop, is reported here. It encodes a product involved in retrograde transport, Golgi to ER which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 100C6. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. γCop is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0028968
3512 γTub23C &ggr; tubulin;&ggr;-Tub;&ggr;-tub23;&ggr;-Tubulin;&ggr;-tubulin-1;&ggr;zy;&ggr;TUB;&ggr;tub23C;&ggr;Tub23CD;&ggr;tubulin;CG3157;D.m.GAMMA-23C;g-Tubulin;gama-tubulin;gamma tubulin;gamma-;gamma-tubulin;gamma-tubulin-1;GAMMA23C;gammatub;gammaTub23C;gammaTub23CD;gammatubulin;gamma[zy];GTUB γ-Tubulin at 23C fruit fly Drosophila melanogaster The D. melanogaster gene γ-Tubulin at 23C, abbreviated as γTub23C, is reported here. It has also been known in FlyBase as γTub23CD. It encodes a product with guanyl nucleotide binding involved in microtubule-based process which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 23C3--4. It interacts genetically with γTub37C. There are 5 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the larval brain, the imaginal disc and the spermatid and are larval recessive lethal and recessive mitotic. γTub23C is discussed in 118 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 8 studies of mutant phenotypes and 4 molecular studies. FB FBgn0004176
3513 γTub37C &g-Tub37C;&ggr; tubulin;&ggr; Tubulin2;&ggr;-Tub;&ggr;-Tubulin;&ggr;-tubulin-2;&ggr;mat;&ggr;TUB;&ggr;Tub2;&ggr;TUB37C;&ggr;Tub37CD;&ggr;tubulin;CG17566;D.m.GAMMA-37C;female sterile(2)Ted Wright 1;fs(2)TW1;fs(2)TWI;fsTW1;g-Tubulin;gama-tubulin;gamma;gamma Tub37CD;gamma tubulin;gamma-Tub;gamma-tubulin;gamma-tubulin-2;gammaTub37C;gammaTub37CD;gammatubulin;gamma[mat];maternal &ggr;-tubulin;PL10;Rb1011;TW1 γ-Tubulin at 37C fruit fly Drosophila melanogaster The D. melanogaster gene γ-Tubulin at 37C, abbreviated as γTub37C, is reported here. It has also been known in FlyBase as γTub2 and fs(2)TW1. It encodes a product with putative structural constituent of cytoskeleton involved in microtubule-based process which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-54 and cytologically to 37C7. It interacts genetically with E(γTub37C1), ncd and γTub23C. There are 20 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 17 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the first meiotic metaphase, the cleavage, the spindle and 4 other listed tissues and are female sterile. γTub37C is discussed in 126 references (excluding sequence accessions), dated between 1981 and 2003. These include at least 9 studies of mutant phenotypes, one study of wild-type function and 7 molecular studies. Among findings on γTub37C mutants, mutations in γTub37C show a maternal effect with defects in fertilization or very early embryonic development. Among findings on γTub37C function, γTub37C is essential for nuclear proliferation in the early embryo. FB FBgn0010097
3518 zetaCOP &zgr;COP;CG3948;copz1;CT13124 fruit fly Drosophila melanogaster The D. melanogaster gene &zgr;COP is reported here. It has also been known in FlyBase as CG3948. It encodes a product putatively involved in intracellular protein transport which is a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence contains a clathrin adaptor complex, small chain. It has been mapped cytologically to 73B6. There is one recorded allele, which is wild-type. &zgr;COP is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0040512
3523 14-3-3epsilon 14-3-3;14-3-3&egr;;14-3-3-e;14-3-3e;anon-WO0172774.141;anon-WO02059370.52;CG31196;CT24092;d14-3-3&egr;;D14-3-3e;d14-3-3epsilon;EK3-5;l(3)j2B10;par-5;PAR5;SR3-9;Su(Raf)3B;Suppressor of Ras85D 3-9 fruit fly Drosophila melanogaster The D. melanogaster gene 14-3-3ε is reported here. It has also been known in FlyBase as 14-3-3e, SR3-9, Su(Raf)3B, l(3)j2B10 and par-5. It encodes a product with diacylglycerol-activated/phospholipid dependent protein kinase C inhibitor activity involved in imaginal disc development which is a component of the ring canal (sensu Drosophila). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-62.0 and cytologically to 90F10. It interacts genetically with phl, Ras85D, 14-3-3&zgr;, Dsor1, aop and 4 other listed genes. There are 10 recorded alleles: 9 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic maternal effect cuticle, the embryonic cycle 14, the germ-line clone oocyte and 3 other listed tissues and are larval recessive lethal, viable, recessive sterile, (with 14-3-3εS-696) visible, recessive mitotic, recessive female sterile, (with Df(3R)P14) viable and (with Df(3R)P14) female sterile. 14-3-3ε is discussed in 44 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 9 studies of mutant phenotypes and one study of wild-type function. Among findings on 14-3-3ε function, 14-3-3ε is required to time mitosis in undisturbed post-blastoderm cell cycles and to delay mitosis following irradiation in embryos. FB FBgn0020238
3524 14-3-3zeta 14-3-3;14-3-3&zgr;;2G1;4-3-3 zeta;5.11;549;BEST:GH05075;CG17870;Complementation group K;D14 3 3 protein;D14-3-3;D14-3-3&zgr;;D14-3-3: D14 3 3 protein;D14-3-3zeta;K;l(2)07103;l(2)46CFe;l(2)46Ee;leo;leo: leonardo;leonardo;leonardo 14-3-3;Leonardo-13-3-3;par-5;PAR5 fruit fly Drosophila melanogaster The D. melanogaster gene 14-3-3&zgr; is reported here. It has also been known in FlyBase as 14-3-3, D14-3-3, l(2)07103, leo and par-5. It encodes a product with tryptophan hydroxylase activator activity involved in tryptophan hydroxylase activation which is a component of the ring canal (sensu Drosophila). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46E6--8. It interacts genetically with 14-3-3ε, faf, tor and Src42A. There are 27 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 18 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic lateral epidermis and the somatic clone follicle cell and are embryonic recessive lethal and neurophysiology defective. 14-3-3&zgr; is discussed in 85 references (excluding sequence accessions), dated between 1982 and 2003. These include at least 16 studies of mutant phenotypes, 3 studies of wild-type function and 5 molecular studies. Among findings on 14-3-3&zgr; function, both isoforms of the 14-3-3&zgr; gene are required acutely (as opposed to developmentally) for normal learning and memory. FB FBgn0004907
3526 18SrRNA 18S;18S rDNA;18S RNA;18S rRNA;18SRNA;BEST:GH11893;BEST:GH15369;BEST:LD10585;BEST:LD33742;BEST:LP07011;BEST:SD07466;NEST:bs01c01 fruit fly Drosophila melanogaster The D. melanogaster multicopy gene 18SrRNA is reported here. It has also been known in FlyBase as 18SRNA. It encodes a product which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. 18SrRNA is discussed in 15 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one molecular study. FB FBgn0061475
3527 18w 18 Wheeler;18-Wheeler;18W;CG8896;CT25100;l(2)00053;tlr;tlr-2;toll;Toll like receptor;tolloid-related;wheeler 18 wheeler fruit fly Drosophila melanogaster The D. melanogaster gene 18 wheeler, abbreviated as 18w, is reported here. It encodes a product with transmembrane receptor activity involved in morphogenesis which is localized to the plasma membrane; it is expressed in the embryo (amnioproctodeal invagination, anal pad, anal plate, antennal sense organ and 17 other listed tissues). It has been sequenced and its amino acid sequence contains a TIR domain. It has been mapped cytologically to 56F8. There are 16 recorded alleles: 1 in vitro construct (not available from the public stock centers), 13 classical mutants (2 available from the public stock centers) and 2 wild-type. Loss-of-function mutations have been isolated which affect the leg, the antenna, the wing and the haltere and are larval recessive lethal. 18w is discussed in 66 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 5 studies of mutant phenotypes, one study of wild-type function and 6 molecular studies. Among findings on 18w function, 18w is a critical component of the humoral immune response. FB FBgn0004364
3529 28SrRNA 28S;28S rDNA;28S ribosomal RNA;28S RNA;28S rRNA;28SRNA;BEST:HL02093;BEST:HL02977;BEST:HL03427;BEST:LD41653;NEST:bs10c09;NEST:bs15g08;NEST:bs17g11;NEST:bs30g02 fruit fly Drosophila melanogaster The D. melanogaster multicopy gene 28SrRNA is reported here. It has also been known in FlyBase as 28SRNA. It encodes a product which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. 28SrRNA is discussed in 22 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one molecular study. FB FBgn0061474
3530 2SrRNA 2S rRNA;2SRNA;5.8S and 2S ribosomal rRNA fruit fly Drosophila melanogaster The D. melanogaster multicopy gene 2SrRNA is reported here. It encodes a product which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. 2SrRNA is discussed in 5 references (excluding sequence accessions), dated between 1974 and 2003. FB FBgn0065042
3532 33-13 fruit fly Drosophila melanogaster The D. melanogaster gene 33-13 is reported here. It encodes a product with DNA binding which is a component of the nucleus. It has been mapped cytologically to 65A1--6. There is one recorded allele, which is wild-type. 33-13 is discussed in 3 references, dated between 1998 and 2001. FB FBgn0024507
3534 5-HT1A 5-HT-dro2A;5-HT1ADro;5-HT1ADro;5-HT[[1ADro]];5HT-dro2A;5HT-drp2A;5HT-drp[[2A]];5HT-R2A;5HT-R2A: Serotonin receptor 2A;5HT1A;5HT1ADro;5htdro2a;CG16720;Dm5HTdro2A;DRO2A;Serotonin receptor 2A;serotonin-receptor-2A Serotonin receptor 1A fruit fly Drosophila melanogaster The D. melanogaster gene Serotonin receptor 1A, abbreviated as 5-HT1A, is reported here. It encodes a product with 5-HT1 receptor activity involved in serotonin receptor, phospholipase C activating pathway which is a component of the integral to plasma membrane; it is expressed in the embryo (VUM neuron, embryonic central nervous system and midline). It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily. It has been mapped cytologically to 56B2--5. There is one recorded allele, which is wild-type. 5-HT1A is discussed in 25 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one study of wild-type function and 6 molecular studies. FB FBgn0004168
3535 5-HT1B 5-HT-dro2B;5-HT1BDro;5-HT1BDro;5-HTdro2B;5-HT[[1BDro]];5-HT[[dro2B]];5HT-dro2B;5HT-dro2B;5HT-dro[[2B]];5HT-R2B;5HT-R2B: Serotonin receptor 2B;5htdro2b;CG15113;Dm5HTdro2B;DRO2B;Serotonin receptor 2B Serotonin receptor 1B fruit fly Drosophila melanogaster The D. melanogaster gene Serotonin receptor 1B, abbreviated as 5-HT1B, is reported here. It encodes a product with serotonin receptor activity involved in serotonin receptor, phospholipase C activating pathway which is a component of the integral to plasma membrane; it is expressed in the embryo (bipolar dendrite neuron and ventral midline). It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily. It has been mapped cytologically to 56B1. There is one recorded allele, which is wild-type. 5-HT1B is discussed in 22 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one study of wild-type function and one molecular study. FB FBgn0004572
3536 5-HT2 ;5-HT2Dro;5-HT2;5-HT2Dro;5-HT[[2Dro]];5-HT[[2]];5HT-dro1;5HT-dro[[1]];5HT-R82A;5HT2-Dro;5HT2Dro;5HT2Dro;5HT[[2Dro]];CG1056;Dm5HT2 Serotonin receptor 2 fruit fly Drosophila melanogaster The D. melanogaster gene Serotonin receptor 2, abbreviated as 5-HT2, is reported here. It encodes a product with 5-HT2 receptor activity involved in serotonin receptor signaling pathway which is a component of the plasma membrane; it is expressed in the embryo (central nervous system). It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily. It has been mapped cytologically to 82C4--5. There are 4 recorded alleles: 3 in vitro constructs (none available from the public stock centers) and 1 wild-type. 5-HT2 is discussed in 27 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 4 studies of wild-type function and 4 molecular studies. Among findings on 5-HT2 function, serotinin, acting through the 5-HT2 gene product, is necessary for proper gastrulation. FB FBgn0013743
3537 5-HT7 5-HT-dro;5-HT-dro1;5-HT7Dro;5-HT7;5-HT7Dro;5-HTdro1;5-HTdro1;5-HT[[7Dro]];5-HT[[7]];5-HT[[dro1]];5HT-dro;5HT-dro1;5HT-R1;5HT-R1: Serotonin receptor 1;5HT7Dro;5htdror;CG12073;Dm5HTdro1;DRO1;Serotonin receptor;Serotonin receptor 1 Serotonin receptor 7 fruit fly Drosophila melanogaster The D. melanogaster gene Serotonin receptor 7, abbreviated as 5-HT7, is reported here. It encodes a product with serotonin receptor activity involved in serotonin receptor signaling pathway which is a component of the integral to plasma membrane; it is expressed in the adult (adult head) and embryo (ventral midline). It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily. It has been mapped cytologically to 100B1. There is one recorded allele, which is wild-type. 5-HT7 is discussed in 22 references (excluding sequence accessions), dated between 1990 and 2003. These include at least one study of wild-type function and 4 molecular studies. Among findings on 5-HT7 function, 5-HT7 receptor stimulates adenylate cyclase. FB FBgn0004573
3539 5SrRNA 2S rRNA;5S;5S rDNA;5S RNA;5S rRNA;5S-rDNA;5SrDNA;5SRNA;Dm5S;l(2)03068;PZ03068;RNA X 5S ribosomal RNA fruit fly Drosophila melanogaster The D. melanogaster multicopy gene 5S ribosomal RNA, abbreviated as 5SrRNA, is reported here. It has also been known in FlyBase as 5SRNA and l(2)03068. It encodes a product which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced. It has been mapped cytologically to 56F1--2. There are 5 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive semi-lethal and recessive lethal. 5SrRNA is discussed in 46 references (excluding sequence accessions), dated between 1970 and 2004. These include at least 3 studies of mutant phenotypes, one study of wild-type function and 2 molecular studies. Among findings on 5SrRNA mutants, point mutations introduced in vitro into pre-5SrRNA have been used to determine which regions of the pre-RNA are required for processing. FB FBgn0000002
3542 7SLRNA ;CR32864 RNA 7SL fruit fly Drosophila melanogaster The D. melanogaster RNA-encoding gene RNA 7SL, abbreviated as 7SLRNA, is reported here. It encodes a product putatively involved in SRP-dependent cotranslational membrane targeting which is putatively a component of the signal recognition particle. It has been sequenced. There is one recorded allele, which is wild-type. 7SLRNA is discussed in 3 references (excluding sequence accessions), dated between 1984 and 2002. FB FBgn0000003
3545 a ;Arc;bran;bran: broad angular;broad angular;CG13505;CG6741;E(sda)A arc fruit fly Drosophila melanogaster The D. melanogaster gene arc, abbreviated as a, is reported here. It has also been known in FlyBase as CG13505 and CG6741. It encodes a product involved in eye morphogenesis (sensu Drosophila) which is localized to the adherens junction; it is expressed in the embryo (Malpighian tubule, embryonic/larval foregut, embryonic/larval hindgut, embryonic/larval salivary gland and posterior midgut primordium) and larva (morphogenetic furrow). It has been sequenced and its amino acid sequence contains a PDZ domain (also known as DHR or GLGF). It has been mapped by recombination to 2-99.2 and cytologically to 58C1--5. It interacts genetically with svr. There are 27 recorded alleles: 26 classical mutants (4 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and the crossvein and are recessive visible. a is discussed in 31 references (excluding sequence accessions), dated between 1919 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 2 molecular studies. Among findings on a function, a may affect eye development by modulating adherens junctions of the developing ommatidia. FB FBgn0000008
3551 Aats-ala ;Alanyl-tRNA synthetase;AlaRS;alaS;ARS;CG13391;CG3017 Alanyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene Alanyl-tRNA synthetase, abbreviated as Aats-ala, is reported here. It encodes a product with alanine-tRNA ligase activity (EC:6.1.1.7) involved in alanyl-tRNA aminoacylation which is expressed in the embryo (embryonic/larval salivary gland). It has been sequenced and its amino acid sequence contains an alanyl-tRNA synthetase and a DHHA1 domain. It has been mapped cytologically to 29B3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Aats-ala is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0027094
3552 Aats-ala-m ;AlaS;CG4633;Dm mt AlaRS mitochondrial alanyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene mitochondrial alanyl-tRNA synthetase, abbreviated as Aats-ala-m, is reported here. It encodes a product with alanine-tRNA ligase activity (EC:6.1.1.7) involved in alanyl-tRNA aminoacylation which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an alanyl-tRNA synthetase. It has been mapped cytologically to 64C7. There is one recorded allele, which is wild-type. Aats-ala-m is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0028962
3562 Aats-leu ;CG7479;Leucyl-tRNA synthetase;LeuRS;LRS Leucyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene Leucyl-tRNA synthetase, abbreviated as Aats-leu, is reported here. It has also been known in FlyBase as CG7479. It encodes a product with leucine-tRNA ligase activity (EC:6.1.1.4) involved in leucyl-tRNA aminoacylation which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains an aminoacyl-transfer RNA synthetases class-I, a t-RNA synthetase, class Ia and a leucyl-tRNA synthetase. It has been mapped cytologically to 64C1. There is one recorded allele, which is wild-type. Aats-leu is discussed in 9 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 3 molecular studies. FB FBgn0027085
3564 Aats-met ;CG31322;CG8684;CG9612;Methionyl-tRNA synthetase;MetRS;MRS Methionyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene Methionyl-tRNA synthetase, abbreviated as Aats-met, is reported here. It has also been known in FlyBase as CG8684 and CG9612. It encodes a product with methionine-tRNA ligase activity (EC:6.1.1.10) involved in methionyl-tRNA aminoacylation which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a t-RNA synthetase, class Ia and a methionyl-tRNA synthetase. It has been mapped cytologically to 88B1. There is one recorded allele, which is wild-type. Aats-met is discussed in 11 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 3 molecular studies. FB FBgn0027083
3565 Aats-phe 3.2;CG13348;CG17962;DMZ60MEX;FRS;fruhstart;frustart;Phenylalanyl-tRNA synthetase;PheRS;Pts;z600 Phenylalanyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene Phenylalanyl-tRNA synthetase, abbreviated as Aats-phe, is reported here. It encodes a product with phenylalanine-tRNA ligase activity (EC:6.1.1.20) involved in phenylalanyl-tRNA aminoacylation which is expressed in the embryo (embryonic/larval muscle system). It has been sequenced and its amino acid sequence contains an aminoacyl-transfer RNA synthetases class-II and a phenylalanyl-tRNA synthetase. It has been mapped cytologically to 50C20. There is one recorded allele, which is wild-type. Aats-phe is discussed in 10 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 7 molecular studies. FB FBgn0020766
3566 Aats-phe-m ;mitochondrial phenylalanyl-tRNA synthetase;mtPheRS mitochondrial phenylalanyl-tRNA synthetase fruit fly Drosophila melanogaster The D. melanogaster gene mitochondrial phenylalanyl-tRNA synthetase, abbreviated as Aats-phe-m, is reported here. It has also been known in FlyBase as mt:Aats-phe. It encodes a product with phenylalanine-tRNA ligase activity (EC:6.1.1.20) involved in phenylalanyl-tRNA aminoacylation which is a component of the mitochondrion. There is one recorded allele, which is wild-type. Aats-phe-m is discussed in one reference, dating from 1999. FB FBgn0028548
3574 ab ;CG4807;clu;clu: clueless;clueless;l(2)k02807;parted;ptd abrupt fruit fly Drosophila melanogaster The D. melanogaster gene abrupt, abbreviated as ab, is reported here. It has also been known in FlyBase as l(2)k02807. It encodes a product with specific RNA polymerase II transcription factor activity involved in axon choice point recognition which is localized to the nucleus; it is expressed in the embryo (VUM precursor, embryonic stomatogastric nervous system, epidermis, larval muscle system and ventral midline) and larva (dorsal mesothoracic disc, eye-antennal disc and imaginal disc). It has been sequenced and its amino acid sequence contains a BTB/POZ domain and a zinc finger, C2H2 type. It has been mapped by recombination to 2-44.0 and cytologically to 32E1--2. It interacts genetically with N and rho. There are 17 recorded alleles: 16 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the abdominal posterior fascicle, the abdominal transverse nerve, the abdominal 2 to 7 dorsal acute muscle 3 and 8 other listed tissues and are recessive male sterile. ab is discussed in 49 references (excluding sequence accessions), dated between 1925 and 2003. These include at least 5 studies of mutant phenotypes, one study of wild-type function and 5 molecular studies. Among findings on ab mutants, mutations in ab affect individual longitudinal veins: vein specific effects. Among findings on ab function, ab encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections. FB FBgn0000011
3576 abd-A abd A;Abd-A;AbdA;abdominal-A;Cbxd;Cbxd: Contrabithoraxoid;CG10325;Contrabithoraxoid;DmabdA;Hab;Hab: Hyperabdominal;Hyperabdominal;i;iab;iab-2;iab-3;iab-4;iab-5;iab2;iab2: infra-abdominal 2;iab3;iab3: infra-abdominal 3;iab4;iab4: infra-abdominal 4;infra-abdominal 2;infra-abdominal 3;infra-abdominal 4;infraabdominal;jabanero;l(3)89Ec;Ultraabdominal abdominal A fruit fly Drosophila melanogaster The D. melanogaster gene abdominal A, abbreviated as abd-A, is reported here. It encodes a product with specific RNA polymerase II transcription factor activity involved in oenocyte development which is localized to the nucleus; it is expressed in the embryo (ISN, abdominal 4-7 vental intersegmental neuron, amnioserosa, anterior and 18 other listed tissues) and larva (dorsal mesothoracic disc, female genital disc and male genital disc). It has been sequenced and its amino acid sequence contains a homeobox domain and a 'Homeobox' antennapedia-type domain. It has been mapped by recombination to 3-58.8 and cytologically to 89E2. It interacts genetically with su(Hw), Ubx, Abd-B, Dfd, lab and 5 other listed genes. There are 80 recorded alleles: 5 in vitro constructs (1 available from the public stock centers), 74 classical mutants (7 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the midgut constriction, the parasegment 7 to 9, the parasegment 10 to 13 and 11 other listed tissues and are homeotic recessive lethal. abd-A is discussed in 437 references (excluding sequence accessions), dated between 1963 and 2003. These include at least 20 studies of mutant phenotypes, 18 studies of wild-type function, 3 studies of natural polymorphisms and 49 molecular studies. Among findings on abd-A mutants, recessive mutations of the Hab group of abd-A alleles have been isolated as revertants of a dominant gain-of-function abd-A mutation. Among findings on abd-A function, a burst of abd-A expression in the postembryonic neuroblasts specifies the time at which apoptosis occurs, determining the number of progeny generated by each neuroblast. (However, there is much more information on function so that may not be representative.) FB FBgn0000014
3577 Abd-B Abd B;ABDB;AbdB(CA)26;AbdB-I;AbdB-II;Abdominal-B;AdbB;CG10291;CG11648;DROABDB;FAB;Fab-7;Fab7;iab;iab-5;iab-6;iab-7;iab-8;iab5;iab5: infra-abdominal 5;iab6;iab6: infra-abdominal 6;iab7;iab7: infra-abdominal 7;iab8;iab8.9;iab8: infra-abdominal 8;iab9;iab9:;infra-abdominal 5;infra-abdominal 6;infra-abdominal 7;infra-abdominal 8;infra-abdominal 9;infraabdominal;infraabdominal-8.9;l(3)89Ed;Male chauvinist pigmentation;Mc;MCP;Mcp: Miscadastral pigmentation;Microcephalus;Miscadastral pigmentation;pH189;Sab;Sab: Superabdominal;Superabdominal;Tab;Tab: Transabdominal;Transabdominal;tuh-3;twig;Uab-5Sab Abdominal B fruit fly Drosophila melanogaster The D. melanogaster gene Abdominal B, abbreviated as Abd-B, is reported here. It has also been known in FlyBase as CG10291, CG11648, MS:AbdB.CA26, MS:DROABDB and Mc. It encodes a product with specific RNA polymerase II transcription factor activity involved in pigmentation which is localized to the nucleus; it is expressed in the embryo (Malpighian tubule, ectoderm, epidermis, parasegment 10 and 15 other listed tissues) and larva (female genital disc and male genital disc). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 3-58.8 and cytologically to 89E4--5. It interacts genetically with Pcl, tuh1, Ubx, Scm, ph-d and 15 other listed genes. There are 184 recorded alleles: 13 in vitro constructs (none available from the public stock centers), 170 classical mutants (12 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the somatic clone abdominal segment 5 to 8, the embryonic somatic clone abdominal segment 8, the somatic clone sclerite and 9 other listed tissues and are dominant male sterile, dominant female sterile, recessive lethal, homeotic somatic clone visible, somatic clone (with Df(3R)P9) body color defective and (with Df(3R)P9) lethal. Abd-B is discussed in 490 references (excluding sequence accessions), dated between 1944 and 2003. These include at least 24 studies of mutant phenotypes, 18 studies of wild-type function, 4 studies of natural polymorphisms and 49 molecular studies. Among findings on Abd-B mutants, recessive Mcp group mutations of Abd-B have been isolated as revertants and partial revertants of dominant gain-of-function Abd-B alleles. Among findings on Abd-B function, Abd-B divides the primordium of the posterior spiracle into two cell populations that develop using distinct morphogenetic mechanisms into the spiracular chamber and the stigmatophore. (However, there is much more information on function so that may not be representative.) FB FBgn0000015
3579 Abl 4674;Abelson;abl;abl kinase;Abl oncogene;Abl1;Ableson;AblK;Am ABL;c-abl;cAbl;CG4032;D-abelson;D-abl;D-ash;DAbl;Dash;Ddash/abl;DROTKABL3;Dsrc7;l(3)04674;l(3)73B;l(3)73Ba;l(3)c-abl Abl tyrosine kinase fruit fly Drosophila melanogaster The D. melanogaster gene Abl tyrosine kinase, abbreviated as Abl, is reported here. It has also been known in FlyBase as CG4032 and l(3)04674. It encodes a product with protein-tyrosine kinase activity (EC:2.7.1.112) involved in axon guidance which is localized to the axon; it is expressed in the embryo (embryonic central nervous system) and ovary (oocyte and ovary). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a src homology 2 (SH2) domain and a tyrosine kinase catalytic domain. It has been mapped cytologically to 73B1--4. It interacts genetically with ena, Dab, fax, Lar, robo and 15 other listed genes. There are 25 recorded alleles: 14 in vitro constructs (none available from the public stock centers), 10 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the central nervous system, the longitudinal connective, the commissure and 4 other listed tissues and are pupal recessive lethal, reduced (with Df(3L)st-j7) viable and neuroanatomy defective. Abl is discussed in 185 references (excluding sequence accessions), dated between 1981 and 2003. These include at least 27 studies of mutant phenotypes, 6 studies of wild-type function and 10 molecular studies. Among findings on Abl mutants, Abl mutants show phenotypes in somatic muscles and eye imaginal disks. FB FBgn0000017
3580 abo ;CG6093 abnormal oocyte fruit fly Drosophila melanogaster The D. melanogaster gene abnormal oocyte, abbreviated as abo, is reported here. It has also been known in FlyBase as CG6093. It encodes a product with transcription regulator activity involved in regulation of transcription from Pol II promoter which is a component of the polytene chromosome. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-44.0 and cytologically to 32C1. It interacts genetically with ABO-X. There are 6 recorded alleles: 1 in vitro construct (not available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the extended germ band stage, the embryonic head and the embryonic cuticle and are female sterile and rescuable maternal effect lethal. abo is discussed in 39 references (excluding sequence accessions), dated between 1960 and 2003. These include at least 4 studies of mutant phenotypes, one study of wild-type function and 2 molecular studies. Among findings on abo mutants, maintained homozygous abo stocks show a decrease in maternally-induced embryonic lethality over time. Among findings on abo function, abo appears to be a negative regulator of histone transcription. FB FBgn0000018
3582 abs ABS;abstract;anon-WO0118547.315;CG14637;DmRH23;l(3)00620;l(3)04505;l(3)06862;l(3)06863 abstrakt fruit fly Drosophila melanogaster The D. melanogaster gene abstrakt, abbreviated as abs, is reported here. It has also been known in FlyBase as l(3)00620. It encodes a product with ATP dependent helicase activity involved in establishment of cell polarity which is a component of the nucleus; it is expressed in the embryo (ubiquitous). It has been sequenced and its amino acid sequence contains a DEAD/DEAH box helicase, a helicase C-terminal domain and a zn-finger CCHC type. It has been mapped cytologically to 82A1. It interacts genetically with rpr. There are 21 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 16 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the retina, the (with absE2) ommatidium, the ectopic (with absE2) photoreceptor cell and 2 other listed tissues and are larval (with absE2) lethal. abs is discussed in 19 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of mutant phenotypes, 2 studies of wild-type function and 6 molecular studies. Among findings on abs function, abs is essential for survival at all stages throughout the life cycle. FB FBgn0015331
3583 ac 990 E5 F1;Ac;Ac: Argentine Curly;achaete-scute;AS-C T5;AS-C T5ac;ASC;ascT5;CG3796;EG:125H10.3;Hairy wing;Hairy-wing;Hw;Hw: Hairy-wing;sc/T5;T5 achaete fruit fly Drosophila melanogaster The D. melanogaster gene achaete, abbreviated as ac, is reported here. It encodes a product with DNA binding involved in neurogenesis which is localized to the nucleus; it is expressed in the embryo (cephalic furrow, ectoderm, embryonic central nervous system, embryonic peripheral nervous system and 16 other listed tissues) and larva (dorsal mesothoracic disc, ectoderm, proneural cluster, sensillum precursor and 2 other listed tissues). It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain and a myc-type, helix-loop-helix dimerization domain. It has been mapped by recombination to 1-0.0 and cytologically to 1A5--6. It interacts genetically with h, Oce, Egfr, su(sc), rho and 4 other listed genes. There are 37 recorded alleles: 15 in vitro constructs (none available from the public stock centers), 21 classical mutants (6 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the anterior dorsocentral bristle, the posterior dorsocentral bristle, the anterior supraalar bristle and 6 other listed tissues and are recessive visible. ac is discussed in 556 references (excluding sequence accessions), dated between 1918 and 2003. These include at least 72 studies of mutant phenotypes, one study of wild-type function, 6 studies of natural polymorphisms and 21 molecular studies. FB FBgn0000022
3589 Ace AcChE;ACE;acetylcholinesterase;AChE;CG17907;CHE;dAChE;DmAChE;FBgn0000024;l(3)26;l(3)87Ed Acetylcholine esterase fruit fly Drosophila melanogaster The D. melanogaster gene Acetylcholine esterase, abbreviated as Ace, is reported here. It encodes a product with acetylcholinesterase activity (EC:3.1.1.7) involved in response to carbamate which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an esterase/lipase/thioesterase family active site, a cholinesterase, an insect acetylcholinesterase and a carboxylesterases type-B. It has been mapped by recombination to 3-52.5 and cytologically to 87E2--3. There are 61 recorded alleles: 15 in vitro constructs (none available from the public stock centers), 44 classical mutants (1 available from the public stock centers) and 2 wild-type. Loss-of-function mutations have been isolated which affect the somatic clone central nervous system and are embryonic recessive lethal, somatic clone optomotor behavior defective, somatic clone visual behavior defective and somatic clone courtship defective. Ace is discussed in 109 references (excluding sequence accessions), dated between 1964 and 2003. These include at least 10 studies of mutant phenotypes, one study of wild-type function and 9 molecular studies. Among findings on Ace function, in situ hybridization studies imply that the non-CNS-specific Ace can also be non-neuronal. FB FBgn0000024
3591 Acf1 ACF;Acf-1;ACF1;ATP-utilizing chromatin assembly and remodeling factor;CAF;CG1966;CHRAC;CHRAC-175;Chromatin Accessibility Complex;dACF;dCHRAC;p170/p185 ATP-dependent chromatin assembly factor large subunit fruit fly Drosophila melanogaster The D. melanogaster gene ATP-dependent chromatin assembly factor large subunit, abbreviated as Acf1, is reported here. It has also been known in FlyBase as Acf. It encodes a product with DNA binding involved in nucleosome spacing which is a component of the ACF complex. It has been sequenced and its amino acid sequence contains a PHD-finger. It has been mapped cytologically to 100D2. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Acf1 is discussed in 51 references (excluding sequence accessions), dated between 1997 and 2003. These include at least 2 studies of wild-type function and 2 molecular studies. Among findings on Acf1 function, in chromatin remodelling, Acf1 is able to modulate the internucleosomal spacing of chromatin by an ATP-dependent mechanism. FB FBgn0027620
3592 achi ;achintya;CG8819;zaa;zuker-aly-like a achintya fruit fly Drosophila melanogaster The D. melanogaster gene achintya, abbreviated as achi, is reported here. It has also been known in FlyBase as CG8819, achintya and zaa. It encodes a product with transcription factor activity involved in spermatogenesis which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 2-65.5 and cytologically to 49A13--B1. There are 11 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 7 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are viable and partially male sterile. achi is discussed in 16 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 studies of wild-type function and 4 molecular studies. Among findings on achi function, achi is required during spermatogenesis. FB FBgn0033749
3597 acj6 Abnormal chemosensory jumb;ACJ6;CG9151;I-POU;Ipou;tI-POU;Twin of I-POU abnormal chemosensory jump 6 fruit fly Drosophila melanogaster The D. melanogaster gene abnormal chemosensory jump 6, abbreviated as acj6, is reported here. It has also been known in FlyBase as CG9151 and Ipou. It encodes a product with transcription corepressor activity involved in response to chemical substance which is a component of the nucleus; it is expressed in the embryo (CQ neuron, EL neuron, RP1 neuron, anterior corner cell and 4 other listed tissues). It has been sequenced and its amino acid sequence contains a 'POU' domain and a homeobox domain. It has been mapped by recombination to 1-49.4 and cytologically to 13B8--C1. It interacts genetically with vvl. There are 11 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 8 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the antennal sensillum, the maxillary palp sense organ and the (with acj66) lamina plexus and are recessive chemosensitive behavior defective, recessive neurophysiology defective, larval behavioral, recessive olfaction defective, chemical sensitive, larval recessive locomotor behavior defective and adult (with acj66) locomotor behavior defective. acj6 is discussed in 60 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 7 studies of mutant phenotypes, 2 studies of wild-type function and 3 molecular studies. Among findings on acj6 function, acj6 may regulate dendritic targeting and coordinate dendritic and axonal connectivity of projection neurons in the olfactory system to ensure the highly stereotypes acquisition and delivery of olfactory information by the central olfactory neurons. FB FBgn0000028
3603 Acon ;ACON-1;aconitase;AconM;BEST:GH10550;CG9244;FBgn0010100;i204;i59;l(2)07054;m-acon;m-Aconitase;mAc;mitochondrial aconitase Aconitase fruit fly Drosophila melanogaster The D. melanogaster gene Aconitase, abbreviated as Acon, is reported here. It has also been known in FlyBase as CG9244 and l(2)07054. It encodes a product with aconitate hydratase activity (EC:4.2.1.3) putatively involved in amino acid biosynthesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an aconitase C-terminal domain. It has been mapped cytologically to 39A7. There are 13 recorded alleles: 12 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. Acon is discussed in 22 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 2 studies of mutant phenotypes and 2 molecular studies. FB FBgn0010100
3623 Act42A 42A actin.;A;act 42A;act42A;actin;BAP47;C;C: Group C;CG12051 Actin 42A fruit fly Drosophila melanogaster The D. melanogaster gene Actin 42A, abbreviated as Act42A, is reported here. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the actin filament; it is expressed in the embryo (embryonic/larval midgut, embryonic/larval proventriculus, gonad, supraesophageal ganglion and ventral nerve cord). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 42A4. There are 4 recorded alleles: 1 in vitro construct (not available from the public stock centers), 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Act42A is discussed in 89 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 7 molecular studies. FB FBgn0000043
3624 Act57B act 57A;Act57A;Actin;anon-84Ea;anon-EST:CL2c12;BEST:RE38067;C;C: Group C;CG10067;CG2846;CG30294;M;M: M repeat;T10;transcript C Actin 57B fruit fly Drosophila melanogaster The D. melanogaster gene Actin 57B, abbreviated as Act57B, is reported here. It has also been known in FlyBase as Act57A, anon-EST:CL2c12 and anon-ESTCL2c12. It encodes a product with putative structural constituent of cytoskeleton involved in heart development which is a component of the actin filament; it is expressed in the embryo (larval muscle system and mesoderm) and larva (larval somatic muscle and pharyngeal muscle). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 57B5. There are 4 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which are larval (with Df(2R)E2) lethal. Act57B is discussed in 57 references (excluding sequence accessions), dated between 1980 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 3 molecular studies. FB FBgn0000044
3625 Act5C &bgr;-actin/Bap47;5C actin;A;Ac5C;act 5C;actin;actin 5C;actin A1;anon-EST:fe2D2;anon-fast-evolving-2D2;Bap47;CG4027;cyt5C;l(;l(1)G0009;l(1)G0010;l(1)G0025;l(1)G0079;l(1)G0117;l(1)G0177;l(1)G0245;l(1)G0330;l(1)G0420;l(1)G0486;M32055;T11 Actin 5C fruit fly Drosophila melanogaster The D. melanogaster gene Actin 5C, abbreviated as Act5C, is reported here. It has also been known in FlyBase as l(1)G0009, l(1)G0010, l(1)G0025, l(1)G0079, l(1)G0117, l(1)G0177, l(1)G0245, l(1)G0330, l(1)G0420 and l(1)G0486. It encodes a product with putative structural constituent of cytoskeleton involved in sperm individualization which is a component of the actin filament; it is expressed in the embryo (anterior embryonic/larval midgut, embryonic central nervous system, posterior embryonic/larval midgut, subesophageal ganglion and 2 other listed tissues). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 5C7. There are 35 recorded alleles: 12 in vitro constructs (1 available from the public stock centers), 22 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are larval lethal. Act5C is discussed in 171 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 3 studies of mutant phenotypes, 3 studies of wild-type function, one study of natural polymorphisms and 12 molecular studies. Among findings on Act5C function, Act5C has a role in the individualization during spermatogenesis. FB FBgn0000042
3626 Act79B 79B Actin;act 79B;act79B;actin;CG5893;CG7478;D;mus79B Actin 79B fruit fly Drosophila melanogaster The D. melanogaster gene Actin 79B, abbreviated as Act79B, is reported here. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 79A6--7. There is one recorded allele, which is wild-type. Act79B is discussed in 54 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 2 molecular studies. FB FBgn0000045
3627 Act87E act 87E;Actin;CG18290;E;mus87E Actin 87E fruit fly Drosophila melanogaster The D. melanogaster gene Actin 87E, abbreviated as Act87E, is reported here. It has also been known in FlyBase as CG18290. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the actin filament; it is expressed in the larva (larval muscle system). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 87E11. There is one recorded allele, which is wild-type. Act87E is discussed in 46 references (excluding sequence accessions), dated between 1980 and 2003. These include at least one study of natural polymorphisms and 7 molecular studies. FB FBgn0000046
3628 Act88F 88F actin;act 88F;Act(88F);Act88-F;actin;anon-EST:CL1a5;arthrin;BEST:LD10566;CG15026;CG32594;CG3331;CG5178;CG5530;E;E protein;Gene A;Ifm(3)7;rsd Actin 88F fruit fly Drosophila melanogaster The D. melanogaster gene Actin 88F, abbreviated as Act88F, is reported here. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-57.1 and cytologically to 88F5. It interacts genetically with Mhc and fln. There are 81 recorded alleles: 41 in vitro constructs (none available from the public stock centers), 39 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the wing and are dominant flightless and recessive visible. Act88F is discussed in 138 references (excluding sequence accessions), dated between 1980 and 2003. These include at least 9 studies of mutant phenotypes, 2 studies of wild-type function, 2 studies of natural polymorphisms and 4 molecular studies. Among findings on Act88F function, Act88F functions in the leg and uterine muscles, though to a lower level than in the IFMs. FB FBgn0000047
3630 Actn &agr;-Actinin;a-actinin;Alpha-actinin;CG3757;CG4376;CT14163;CT14232;EG:133E12.1;fliA;fliA: flightless-A;flightless A;flightless-A;GA17;HM-29;l(1)2Cb;l(1)EA82;lethal(1)2cb;y α actinin fruit fly Drosophila melanogaster The D. melanogaster gene α actinin, abbreviated as Actn, is reported here. It encodes a product with actin cross-linking activity putatively involved in cytoskeletal anchoring which is putatively a component of the focal adhesion. It has been sequenced and its amino acid sequence contains a phytochrome and a EF-hand family. It has been mapped cytologically to 2C4--7. It interacts genetically with wupA and vri. There are 25 recorded alleles: 24 classical mutants (4 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the somatic muscle and are larval recessive lethal and larval recessive locomotor behavior defective. Actn is discussed in 64 references (excluding sequence accessions), dated between 1977 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and 8 molecular studies. FB FBgn0000667
3632 Actr13E Acrp;actin-related protein;ARP;ARP(13E);Arp13E;Arp4;CG11678 Actin-related protein 13E fruit fly Drosophila melanogaster The D. melanogaster gene Actin-related protein 13E, abbreviated as Actr13E, is reported here. It encodes a product with structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 13E12. There is one recorded allele, which is wild-type. Actr13E is discussed in 15 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 2 molecular studies. FB FBgn0011741
3641 Ada2A ADA2A;CG31318;CG7150;dAda2A fruit fly Drosophila melanogaster The D. melanogaster gene Ada2A is reported here. It has also been known in FlyBase as CG7150. It encodes a product with histone acetyltransferase activity (EC:2.3.1.48) putatively involved in regulation of transcription from Pol II promoter which is a component of the Ada2/Gcn5/Ada3 transcription activator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 90F10--11. There is one recorded allele, which is wild-type. Ada2A is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0051318
3642 Ada2S ADA2b;BcDNA:LD24527;CG9638;dAda2b;dAda2S;Transcriptional adapter 2S Transcriptional adapter 2S fruit fly Drosophila melanogaster The D. melanogaster gene Transcriptional adapter 2S, abbreviated as Ada2S, is reported here. It has also been known in FlyBase as CG9638. It encodes a product with histone acetyltransferase activity (EC:2.3.1.48) putatively involved in regulation of transcription from Pol II promoter which is a component of the SAGA complex. It has been sequenced and its amino acid sequence contains a myb DNA binding domain. It has been mapped cytologically to 84F5. There is one recorded allele, which is wild-type. Ada2S is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037555
3649 Adf1 Adf 1;Adf-1;CG15845;l(2)01349;l(2)04065;nal;nalyot;naylot Adh transcription factor 1 fruit fly Drosophila melanogaster The D. melanogaster gene Adh transcription factor 1, abbreviated as Adf1, is reported here. It has also been known in FlyBase as CG15845, l(2)01349, l(2)04065 and nal. It encodes a product with RNA polymerase II transcription factor activity involved in synaptogenesis which is localized to the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 42C3. There are 41 recorded alleles: 30 in vitro constructs (none available from the public stock centers), 10 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the bouton and are recessive memory defective and neuroanatomy defective. Adf1 is discussed in 48 references (excluding sequence accessions), dated between 1985 and 2003. These include at least one study of wild-type function, one study of natural polymorphisms and 7 molecular studies. Among findings on Adf1 function, Adf1 may be a critical regulatory switch involved in terminal stages of synapse maturation. FB FBgn0000054
3658 Adk2 Adenylate kinase-2;ADK-2;anon-Dak2;BcDNA:SD09634;CG3140;Dak2 Adenylate kinase-2 fruit fly Drosophila melanogaster The D. melanogaster gene Adenylate kinase-2, abbreviated as Adk2, is reported here. It has also been known in FlyBase as BcDNA:SD09634, CG3140 and anon-Dak2. It encodes a product with adenylate kinase activity (EC:2.7.4.3) involved in ADP biosynthesis which is a component of the mitochondrial intermembrane space. It has been sequenced and its amino acid sequence contains an adenylate kinase. It has been mapped cytologically to 60B4. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Adk2 is discussed in 16 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 3 molecular studies. FB FBgn0022708
3660 Adk3 Adenylate kinase-3;AK3;bs12h03.y1;CG6612;DAK3 Adenylate kinase-3 fruit fly Drosophila melanogaster The D. melanogaster gene Adenylate kinase-3, abbreviated as Adk3, is reported here. It has also been known in FlyBase as CG6612. It encodes a product with adenylate kinase activity (EC:2.7.4.3) involved in ADP biosynthesis which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains an adenylate kinase. It has been mapped cytologically to 86C7. There is one recorded allele, which is wild-type. Adk3 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0042094
3664 Aef1 Adh enhancer factor 1;AEF-1;CG5683 Adult enhancer factor 1 fruit fly Drosophila melanogaster The D. melanogaster gene Adult enhancer factor 1, abbreviated as Aef1, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in negative regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 78D2. There are 7 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 1 classical mutant (available from the public stock centers) and 1 wild-type. Aef1 is discussed in 21 references (excluding sequence accessions), dated between 1992 and 2003. These include at least one study of wild-type function and one molecular study. FB FBgn0005694
3665 aft adrift;CG5032;EG:52C10.7 adrift fruit fly Drosophila melanogaster The D. melanogaster gene adrift, abbreviated as aft, is reported here. It has also been known in FlyBase as EG:52C10.7 and adrift. It encodes a product involved in cell migration which is a component of the nucleus; it is expressed in the embryo (embryonic brain, embryonic/larval ganglionic branch, embryonic/larval tracheal system, epidermis and gonad). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 54E9. There are 6 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic/larval ganglionic branch. aft is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on aft mutants, ganglionic tracheal branches migrate normally along the intersegmental nerve in aft mutants, but sporadically fail to switch to the segmental nerve and enter the central nervous system, instead they end up meandering along the ventral epidermis. Among findings on aft function, aft is required for tracheal pathfinding into the CNS. FB FBgn0026309
3671 ago ;anon-WO0118547.345;archipelago;cdc4;CG15010;DmFbw7;SCFAgo archipelago fruit fly Drosophila melanogaster The D. melanogaster gene archipelago, abbreviated as ago, is reported here. It has also been known in FlyBase as CG15010. It encodes a product with ubiquitin-protein ligase activity (EC:6.3.2.19) involved in regulation of mitosis which is a component of the SCF ubiquitin ligase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64A11--12. It interacts genetically with dap and CycE. There are 13 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ectopic somatic clone secondary pigment cell, the ectopic somatic clone tertiary pigment cell, the ectopic somatic clone interommatidial bristle and the somatic clone mitotic cycle and are somatic clone increased cell number and somatic clone mitotic. ago is discussed in 23 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function and one molecular study. FB FBgn0041171
3680 Akt1 AKT;AKT/PKB;CG4006;D-Akt;Dakt;dAKT/dPKB;dAkt/PKB;dakt1;DAKT1/PKB;DPKB;DRAC-PK;DRAC-PK66; DRAC-PK85;l(3)04226;l(3)89Bq;PKB;PKB/AKT;PKB/dAKT;RAC;RacPK;Related to PKA to;Related to PKA to PKC protein kinases;related to the A and C kinases fruit fly Drosophila melanogaster The D. melanogaster gene Akt1 is reported here. It has also been known in FlyBase as RacPK, l(3)04226 and l(3)89Bq. It encodes a product with protein serine/threonine kinase activity involved in positive regulation of cell size which is a component of the plasma membrane; it is expressed in the ovary (nurse cell). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a protein kinase C-terminal domain and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 89B3. It interacts genetically with foxo, Pten, Thor, Pk61C, Pi3K92E and 4 other listed genes. There are 16 recorded alleles: 10 in vitro constructs (none available from the public stock centers), 5 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the germ-line clone maternal effect embryonic/first instar larval cuticle, the somatic clone rhabdomere, the somatic clone ommatidium and 3 other listed tissues and are recessive lethal, germ-line clone cell death increase, recessive somatic clone visible and somatic clone reduced cell size. Akt1 is discussed in 93 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 14 studies of mutant phenotypes, one study of wild-type function and 7 molecular studies. Among findings on Akt1 function, data implicates Akt1 as a cell survival gene. FB FBgn0010379
3681 al A1;AL;CG3935;L13-4;lambda13-4 aristaless fruit fly Drosophila melanogaster The D. melanogaster gene aristaless, abbreviated as al, is reported here. It encodes a product with specific RNA polymerase II transcription factor activity involved in proximal/distal pattern formation, imaginal disc which is a component of the nucleus; it is expressed in the embryo (embryonic abdominal segment 1 to 8, embryonic antennal segment, embryonic labial segment, embryonic mandibular segment and 4 other listed tissues) and larva (dorsal mesothoracic disc, eye-antennal disc and ventral thoracic disc). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors, a homeobox domain and a OAR domain. It has been mapped by recombination to 2-0.4 and cytologically to 21C2--4. It interacts genetically with ss, th, Antp and Lim1. There are 22 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 16 classical mutants (3 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the arista, the posterior scutellar bristle, the scutellum and 6 other listed tissues and are recessive visible, female mating defective, (with alex) visible and (with Df(2L)al) visible. al is discussed in 96 references (excluding sequence accessions), dated between 1925 and 2003. These include at least 6 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on al function, in the leg, al is only required for the growth and differentiation of the tip of the leg and not for the formation of the proximo-distal axis. FB FBgn0000061
3683 Alas ;CG3017 Aminolevulinate synthase fruit fly Drosophila melanogaster The D. melanogaster gene Aminolevulinate synthase, abbreviated as Alas, is reported here. It encodes a product with 5-aminolevulinate synthase activity (EC:2.3.1.37) involved in amino acid metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains an aminotransferases class-II and an aminolevulinic acid synthase domain. It has been mapped cytologically to 60A14. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Alas is discussed in 14 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 4 molecular studies. FB FBgn0020764
3687 Aldh ACDH;Acetaldehyde dehydrogenase;aldehyde dehydrogenase;CG3752 Acetaldehyde dehydrogenase fruit fly Drosophila melanogaster The D. melanogaster gene Acetaldehyde dehydrogenase, abbreviated as Aldh, is reported here. It encodes a product with aldehyde dehydrogenase (NAD) activity (EC:1.2.1.3) which is localized to the cytoplasm. There is one recorded allele, which is wild-type. Aldh is discussed in 9 references, dated between 1968 and 2002. These include at least one molecular study. FB FBgn0012036
3690 Alg10 ;Alpha 3 glucosyltransferase;CG32076;CG7624 Alpha 3 glucosyltransferase fruit fly Drosophila melanogaster The D. melanogaster gene Alpha 3 glucosyltransferase, abbreviated as Alg10, is reported here. It has also been known in FlyBase as CG7624. It encodes a product with glucosyltransferase activity (EC:2.4.1.-) involved in N-linked glycosylation which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 68A9. There is one recorded allele, which is wild-type. Alg10 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2002. These include at least one molecular study. FB FBgn0052076
3691 Alhambra AF10;Alh;Alhamabra;anon-WO0118547.226;CG1070;Dalf;l(3)j13A6;l(3)j8C8 Alhambra fruit fly Drosophila melanogaster The D. melanogaster gene Alhambra is reported here. It has also been known in FlyBase as CG1070. It encodes a product with transcription factor activity involved in molting cycle (sensu Insecta) which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a PHD-finger. It has been mapped cytologically to 84B6--C3. There are 8 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 5 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the larva and the larval nervous system and are recessive developmental rate defective. Alhambra is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037471
3692 alien Alien;BcDNA:LD10463;CG9556;CH2;COP9 complex homolog subunit 2;CSN2;d-Alien;DCH2;Drosophila COP9 signalosome homolog 2 alien fruit fly Drosophila melanogaster The D. melanogaster gene alien is reported here. It has also been known in FlyBase as BcDNA:LD10463 and CH2. It encodes a product with transcription corepressor activity involved in negative regulation of transcription, DNA-dependent which is localized to the cytoplasm; it is expressed in the embryo (abdominal 1 intersegmental apodeme, abdominal 1 intrasegmental apodeme 1, abdominal 1 intrasegmentalapodeme 2, abdominal 2 intersegmental apodeme and 20 other listed tissues). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 29F7. There is one recorded allele, which is wild-type. alien is discussed in 22 references (excluding sequence accessions), dated between 1995 and 2003. These include at least one study of wild-type function and 6 molecular studies. FB FBgn0013746
3693 Alk ;CG8250;DAlk;DAlk53;mili fruit fly Drosophila melanogaster The D. melanogaster gene Alk is reported here. It has also been known in FlyBase as CG8250. It encodes a product with protein-tyrosine kinase activity (EC:2.7.1.112) involved in protein amino acid phosphorylation which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a MAM domain, a tyrosine kinase catalytic domain and a receptor tyrosine kinase class II. It has been mapped cytologically to 53C10. There are 6 recorded alleles: 5 in vitro constructs (none available from the public stock centers) and 1 wild-type. Alk is discussed in 15 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0040505
3695 α-catenin-related alpha-catenin-related;CG2987 fruit fly Drosophila melanogaster The D. melanogaster gene alpha-catenin-related is reported here. It has also been known in FlyBase as CG2987. It encodes a product with actin binding putatively involved in cell adhesion which is a component of the zonula adherens. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60A14. There is one recorded allele, which is wild-type. alpha-catenin-related is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0029105
3697 aly ;BcDNA:LD24793;cg1101;CG2075;dmREF1;l(3)02267;ms(3)2;ms(3)ry2;ref1 always early fruit fly Drosophila melanogaster The D. melanogaster gene always early, abbreviated as aly, is reported here. It has also been known in FlyBase as CG2075, ms(3)2 and ms(3)ry2. It encodes a product involved in spermatogenesis which is a component of the cytoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-4.4 and cytologically to 63A3. It interacts genetically with comr. There are 13 recorded alleles: 12 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the conditional ts testis and the conditional ts spermatocyte and are recessive male sterile and recessive meiotic. aly is discussed in 37 references (excluding sequence accessions), dated between 1982 and 2003. These include at least 4 studies of mutant phenotypes, 3 studies of wild-type function and 3 molecular studies. Among findings on aly mutants, mutations of aly affect the morphology and behavior of the mitotic spindles of embryonic cleavage divisions to produce multipolar spindles in male meiosis and generate abnormal mitotic figures in larval neuroblasts. Among findings on aly function, aly may regulate cell cycle progression and terminal differentiation during male gametogenesis by regulating chromatin conformation in primary spermatocytes. FB FBgn0004372
3699 Ama AMA;amalgam;BG:DS00276.6;CG2198;CT7244;M109 Amalgam fruit fly Drosophila melanogaster The D. melanogaster gene Amalgam, abbreviated as Ama, is reported here. It has also been known in FlyBase as M109. It encodes a product with antigen binding involved in cell adhesion which is localized to the plasma membrane; it is expressed in the embryo (amnioserosa, embryonic central nervous system, embryonic/larval dorsal vessel, fat body and 7 other listed tissues). It has been sequenced and its amino acid sequence contains an immunoglobulin and major histocompatibility complex domain, an immunoglobulin C-2 type and an immunoglobulin-like. It has been mapped cytologically to 84A5. It interacts genetically with Abl. There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Ama is discussed in 38 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 2 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies. FB FBgn0000071
3704 amos Amos;asolo;CG10393;Roi;rolo;Rough eye;Tft;Tufted absent MD neurons and olfactory sensilla fruit fly Drosophila melanogaster The D. melanogaster gene absent MD neurons and olfactory sensilla, abbreviated as amos, is reported here. It has also been known in FlyBase as Roi, Tft and rolo. It encodes a product with transcription factor activity involved in sensory organ determination which is a component of the nucleus; it is expressed in the embryo (abdominal segment, antenno-maxillary complex, cellular blastoderm, embryonic antennal segment and 5 other listed tissues), ovary (centripetally migrating follicle cell, nurse cell and oocyte) and prepupa and pupa (antennal disc, olfactory sensory organ and tarsus). It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain. It has been mapped by recombination to 2-53.6 and cytologically to 36F6. It interacts genetically with da, hh, ro, ato, Dr and 9 other listed genes. There are 11 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 5 classical mutants (2 available from the public stock centers) and 3 wild-type. Hypomorphic mutations have been isolated which affect the dorsal abdominal cluster, the dorsal multidendritic neuron and the abdominal dorsal bipolar neuron dbp and are recessive lethal. amos is discussed in 47 references (excluding sequence accessions), dated between 1952 and 2003. These include at least 8 studies of mutant phenotypes, 3 studies of wild-type function and 4 molecular studies. Among findings on amos function, amos is a proneural gene for olfactory sensilla, most likely the sensilla basiconica and trichodea. FB FBgn0003270
3705 Amph Amp;amphiphysin;CG8604;DAMP;damph Amphiphysin fruit fly Drosophila melanogaster The D. melanogaster gene Amphiphysin, abbreviated as Amph, is reported here. It has also been known in FlyBase as Amp, amph and amphiphysin. It encodes a product involved in protein localization which is a component of the synapse. It has been sequenced and its amino acid sequence contains an amphiphysin. It has been mapped cytologically to 49B7--8. It interacts genetically with bif. There are 15 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 11 classical mutants (2 available from the public stock centers) and 2 wild-type. Mutations have been isolated which affect the larval neuromuscular junction, the rhabdomere, the motor neuron and the indirect flight muscle and are viable, flightless, larval hypoactive and larval neurophysiology defective. Amph is discussed in 31 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 6 molecular studies. Among findings on Amph function, Amph is involved in the structural organization of the membrane-bound compartments of the excitation-contraction coupling machinery of muscles, but not in synaptic vesicle endocytosis. FB FBgn0027356
3706 amx ;BcDNA:GH02974;CG12127;fs(1)amx almondex fruit fly Drosophila melanogaster The D. melanogaster gene almondex, abbreviated as amx, is reported here. It has also been known in FlyBase as BcDNA:GH02974. It encodes a product with putative endodeoxyribonuclease activity involved in mesoderm development which is putatively a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 8D10. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the eye, the thorax, the rescuable maternal effect epidermis and 6 other listed tissues and are recessive visible, rescuable maternal effect lethal, recessive female sterile and embryonic neurogenic (with Df(1)10-70d) lethal. amx is discussed in 32 references (excluding sequence accessions), dated between 1956 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and one molecular study. FB FBgn0000077
3717 And ACaM;Calmodulin-related 97A;Camr97A;Camr97A: Calmodulin-related 97A;CG17769 Androcam fruit fly Drosophila melanogaster The D. melanogaster gene Androcam, abbreviated as And, is reported here. It has also been known in FlyBase as CG17769 and Camr97A. It encodes a product with calcium ion binding involved in calcium ion sensing which is a component of the cytoplasm. It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 96F3. There is one recorded allele, which is wild-type. And is discussed in 23 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of wild-type function and 6 molecular studies. Among findings on And function, And may have a role in spermatogenesis and mature sperm function. FB FBgn0011273
3718 Ank ANK;ankyrin;CG1651;CG32008;Dank1 Ankyrin fruit fly Drosophila melanogaster The D. melanogaster gene Ankyrin, abbreviated as Ank, is reported here. It encodes a product with structural constituent of cytoskeleton involved in cytoskeletal anchoring which is localized to the plasma membrane; it is expressed in the larva (plasma membrane) and ovary (follicle cell, ovary and spectrosome). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 102A4--6. There are 3 recorded alleles: 2 in vitro constructs (none available from the public stock centers) and 1 wild-type. Ank is discussed in 49 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 5 molecular studies. FB FBgn0011747
3719 Ank2 ;CG7462;Dank2;ESTS:149B10S fruit fly Drosophila melanogaster The D. melanogaster gene Ank2 is reported here. It has also been known in FlyBase as ESTS149B10S and ESTS:149B10S. It encodes a product with structural constituent of cytoskeleton involved in cytoskeletal anchoring which is putatively a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 66A10. There is one recorded allele, which is wild-type. Ank2 is discussed in 16 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 molecular studies. FB FBgn0017645
3727 anon-EST:Liang-1.56 ;clone 1.56 fruit fly Drosophila melanogaster The D. melanogaster gene anon-EST:Liang-1.56 is reported here. It has also been known in FlyBase as anon-1.56. It encodes a product with putative structural constituent of ribosome putatively involved in protein biosynthesis which is putatively a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. anon-EST:Liang-1.56 is discussed in 2 references (excluding sequence accessions), dated between 1998 and 1999. FB FBgn0025982
3728 anon-EST:Liang-1.80 ;clone 1.80 fruit fly Drosophila melanogaster The D. melanogaster gene anon-EST:Liang-1.80 is reported here. It has also been known in FlyBase as anon-1.80. It encodes a product putatively involved in smooth muscle contraction which is putatively a component of the striated muscle thin filament. It has been sequenced. There is one recorded allele, which is wild-type. anon-EST:Liang-1.80 is discussed in 2 references (excluding sequence accessions), dated between 1998 and 1999. FB FBgn0025973
3731 anon-EST:Posey204 fruit fly Drosophila melanogaster The D. melanogaster gene anon-EST:Posey204 is reported here. It has also been known in FlyBase as anon-ESTPosey204. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. FB FBgn0025305
3732 anon-EST:Posey37 fruit fly Drosophila melanogaster The D. melanogaster gene anon-EST:Posey37 is reported here. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. FB FBgn0026273
3733 anon-EST:Posey6 fruit fly Drosophila melanogaster The D. melanogaster gene anon-EST:Posey6 is reported here. It has also been known in FlyBase as anon-ESTPosey6. It encodes a product with putative structural constituent of ribosome putatively involved in protein biosynthesis which is putatively a component of the cytosolic ribosome (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. FB FBgn0025288
3734 anon-MMS23 ;S11 fruit fly Drosophila melanogaster The D. melanogaster gene anon-MMS23 is reported here. It encodes a product with putative structural constituent of ribosome putatively involved in protein biosynthesis which is putatively a component of the cytosolic small ribosomal subunit (sensu Eukarya). There is one recorded allele, which is wild-type. anon-MMS23 is discussed in 2 references, dated between 1997 and 2002. These include at least one study of wild-type function. FB FBgn0025784
3737 Ant2 Adenine nucleotide translocase 2;ADP/ATP translocase.;CG1683;l(1)G0126;l(1)G0247;l(1)G0386 Adenine nucleotide translocase 2 fruit fly Drosophila melanogaster The D. melanogaster gene Adenine nucleotide translocase 2, abbreviated as Ant2, is reported here. It has also been known in FlyBase as l(1)G0126, l(1)G0247 and l(1)G0386. It encodes a product with ATP:ADP antiporter activity involved in ATP/ADP exchange which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial carrier domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 9E10. There are 10 recorded alleles: 1 in vitro construct (not available from the public stock centers), 8 classical mutants (1 available from the public stock centers) and 1 wild-type. Ant2 is discussed in 19 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0025111
3739 Antp 3.4;Ant;ANT-C;ANT-P;ANTC;antp;Antp1;BG:DS07700.1;CG1028;DmAntp;DMANTPE1;DRO15DC96Z;Hu;Hu: Humeral;Humeral;l(3)84Ba;Nasobemia;Ns;Ns: Nasobemia;Scx;Scx: Sex combs extra;Sex comb extra;Sex combs extra Antennapedia fruit fly Drosophila melanogaster The D. melanogaster gene Antennapedia, abbreviated as Antp, is reported here. It has also been known in FlyBase as MS:Antp.3.4. It encodes a product with specific RNA polymerase II transcription factor activity involved in regulation of transcription from Pol II promoter which is localized to the nucleus; it is expressed in the embryo (ectoderm, embryonic abdominal neuromere, embryonic abdominal segment 1 to 7, embryonic central nervous system and 21 other listed tissues) and larva (dorsal mesothoracic disc, dorsal metathoracic disc, dorsal pouch, dorsal prothoracic disc and 9 other listed tissues). It has been sequenced and its amino acid sequence contains a homeobox domain and a 'Homeobox' antennapedia-type domain. It has been mapped by recombination to 3-47.5 and cytologically to 84B1--2. It interacts genetically with Pc, brm, Pcl, Ubx, osa and 29 other listed genes. There are 136 recorded alleles: 41 in vitro constructs (1 available from the public stock centers), 94 classical mutants (64 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the somatic clone mesothoracic leg, the ectopic somatic clone antenna, the somatic clone macrochaeta and 5 other listed tissues and are somatic clone visible. Antp is discussed in 619 references (excluding sequence accessions), dated between 1916 and 2003. These include at least 109 studies of mutant phenotypes, 7 studies of wild-type function, one study of natural polymorphisms and 32 molecular studies. Among findings on Antp mutants, mutations of Antp cause abnormal leg development or thoracic development or both. (However, there is much more information on mutants so that may not be representative.) FB FBgn0000095
3741 aop Aop;Aop/Yan;CG3166;DROYANET;DROYANETSB;pok;pok: pokkuri;pokkuri;SK2-1;yan;yan/pok;yan: yan anterior open fruit fly Drosophila melanogaster The D. melanogaster gene anterior open, abbreviated as aop, is reported here. It has also been known in FlyBase as MS:DROYANET. It encodes a product with specific RNA polymerase II transcription factor activity involved in induction of apoptosis which is localized to the nucleus; it is expressed in the embryo (embryonic/larval tracheal system and epidermis), larva (eye-antennal disc and imaginal disc) and prepupa and pupa (cone cell and pigment cell). It has been sequenced and its amino acid sequence contains an ets-domain, a HSF/ETS DNA-binding domain and a sterile α motif (SAM)/Pointed domain. It has been mapped by recombination to 2-12 and cytologically to 22D1. It interacts genetically with Ras85D, phl, rl, ttk, ksr and 48 other listed genes. There are 52 recorded alleles: 22 in vitro constructs (6 available from the public stock centers), 29 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the (with aoppok-x8) ommatidium, the (with aoppok-x8) eye, the chordotonal organ and 5 other listed tissues and are recessive embryonic lethal, (with aoppok-x8) lethal, (with aoppok-x8) visible and neuroanatomy defective. aop is discussed in 204 references (excluding sequence accessions), dated between 1984 and 2003. These include at least 33 studies of mutant phenotypes, 14 studies of wild-type function, one study of natural polymorphisms and 9 molecular studies. Among findings on aop function, map kinase mediated down-regulation of aop function appears to be critical for the proper differentiation of both neuronal and nonneuronal tissues throughout development. FB FBgn0000097
3742 Aos1 ;CG12276;DmAos1;DmSAE1;SAE1;Smt3 activating enzyme 1;Ubiquitin activating enzyme fruit fly Drosophila melanogaster The D. melanogaster gene Aos1 is reported here. It has also been known in FlyBase as CG12276 and SAE1. It encodes a product with SUMO activating enzyme activity involved in SMT3-dependent protein catabolism. It has been sequenced and its amino acid sequence contains a UBA/THIF-type NAD/FAD binding fold. It has been mapped cytologically to 87B10. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. Aos1 is discussed in 15 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 5 molecular studies. FB FBgn0029512
3743 ap ;blt;CG8376;LIM;no-wings;tornwing;trw;trw: tornwing;Xa;Xa: Xasta;Xasta apterous fruit fly Drosophila melanogaster The D. melanogaster gene apterous, abbreviated as ap, is reported here. It encodes a product with zinc ion binding involved in neurogenesis which is localized to the nucleus; it is expressed in the embryo (chordotonal organ, embryonic brain, embryonic central nervous system, embryonic mandibular segment and 10 other listed tissues) and larva (dorsal mesothoracic disc, dorsal metathoracic disc, eye-antennal disc, larval brain and 4 other listed tissues). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 2-55.2 and cytologically to 41F8. It interacts genetically with Chi, fng, Bx, Ser, wg and 12 other listed genes. There are 90 recorded alleles: 25 in vitro constructs (none available from the public stock centers), 64 classical mutants (10 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the haltere, the embryonic/larval somatic muscle, the abdominal 2 to 7 lateral transverse muscle 1 to 3 and 8 other listed tissues and are (with apmd544) visible and (with apmd544) neuroanatomy defective. ap is discussed in 319 references (excluding sequence accessions), dated between 1914 and 2003. These include at least 39 studies of mutant phenotypes, 17 studies of wild-type function and 18 molecular studies. Among findings on ap mutants, a group of ap alleles, represented by apblt, exhibits a less severe, somewhat different wing phenotype than ap1 or ap4, attributable to localized lysosomal cell death in the presumptive wing blade. Among findings on ap function, ap mediates development of direct flight muscles autonomously and development of indirect flight muscles through epidermal cues. (However, there is much more information on function so that may not be representative.) FB FBgn0000099
3746 AP-2 ;CG7807;DAP-2;dAP-2&agr;;dAP-2alpha;stummelbein fruit fly Drosophila melanogaster The D. melanogaster gene AP-2 is reported here. It encodes a product with specific RNA polymerase II transcription factor activity involved in leg joint morphogenesis (sensu Holometabola) which is a component of the nucleus; it is expressed in the embryo (embryonic protocerebrum, embryonic protocrebral neuromere, embryonic/larval brain, procephalic neurectoderm and 2 other listed tissues) and larva (eye-antennal disc, larval optic lobe, ventral nerve cord and ventral thoracic disc). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 78D8--E1. There are 22 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 19 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the leg, the joint, the proboscis and 3 other listed tissues and are adult recessive lethal and dominant visible. AP-2 is discussed in 15 references (excluding sequence accessions), dated between 1997 and 2004. These include at least one study of wild-type function and 2 molecular studies. FB FBgn0023417
3751 Apc adenomatous polyposis coli;APC;APC-like;APC1;CG1451;D-APC;D-APC1;dApc;dAPC1 APC-like fruit fly Drosophila melanogaster The D. melanogaster gene APC-like, abbreviated as Apc, is reported here. It has also been known in FlyBase as CG1451. It encodes a product with beta-catenin binding involved in negative regulation of transcription, DNA-dependent which is a component of the apicolateral plasma membrane; it is expressed in the embryo (axon, embryonic nervous system, epidermis, longitudinal connectives and 2 other listed tissues). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98E5--6. It interacts genetically with Apc2, arm, pan and sgg. There are 6 recorded alleles: 1 in vitro construct (not available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the photoreceptor cell R1 to 8 and the photoreceptor cell and are recessive conditional ts lethal and viable. Apc is discussed in 86 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 6 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies. FB FBgn0015589
3752 Apc2 APC;APC2;CG6193;D-APC2;dApc2;dAPC2/E-APC;DE-Cadherin;E-APC;E-APC dAPC2;E-APC: Epithelial Adenomatous Polyposis Coli;Epithelial Adenomatous Polyposis Coli Adenomatous polyposis coli tumor suppressor homolog 2 fruit fly Drosophila melanogaster The D. melanogaster gene Adenomatous polyposis coli tumor suppressor homolog 2, abbreviated as Apc2, is reported here. It encodes a product with putative microtubule binding involved in Wnt receptor signaling pathway which is a component of the apicolateral plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95E6. It interacts genetically with Apc and wg. There are 12 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 6 classical mutants (3 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the wing vein, the ommatidium, the chaeta and 6 other listed tissues and are (with Apc2δS) sterile, viable, recessive visible, recessive sterile and embryonic recessive maternal effect lethal. Apc2 is discussed in 68 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 6 studies of mutant phenotypes, one study of wild-type function and 5 molecular studies. FB FBgn0026598
3757 Aph-1 Alkaline phosphatase;AP;APH;CG2855;Dm APH-1;l(2)23AB6;l(2)23Ag;l-Aph;larval Alkaline phosphatase;p-Aph;pen-1;presenilin enhancer-1;presenilin stabilization factor;pupal Alkaline phosphatase Alkaline phosphatase 1 fruit fly Drosophila melanogaster The D. melanogaster gene Alkaline phosphatase 1, abbreviated as Aph-1, is reported here. It encodes a product with alkaline phosphatase activity (EC:3.1.3.1). It has been mapped by recombination to 3-47.3. There are 7 recorded alleles, all wild-type. Aph-1 is discussed in 17 references, dated between 1964 and 2003. These include at least one study of natural polymorphisms. FB FBgn0000106
3758 aph-1 Aph-1;CG2855;Dm APH-1;pen-1;pen-1:presenilin stabilization factor;presenilin enhancer-1 anterior pharynx defective 1 fruit fly Drosophila melanogaster The D. melanogaster gene anterior pharynx defective 1, abbreviated as aph-1, is reported here. It has also been known in FlyBase as CG2855 and pen-1. It encodes a product with endopeptidase activity involved in Notch signaling pathway which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 23A5. There are 3 recorded alleles: 2 in vitro constructs (none available from the public stock centers) and 1 wild-type. aph-1 is discussed in 7 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0031458
3761 Aph-4 Alkaline phosphatase;Alkaline phosphatase-4;AP;Aph;CG1462;l(3)07028;pMY51 Alkaline phosphatase 4 fruit fly Drosophila melanogaster The D. melanogaster gene Alkaline phosphatase 4, abbreviated as Aph-4, is reported here. It has also been known in FlyBase as l(3)07028. It encodes a product with alkaline phosphatase activity (EC:3.1.3.1) involved in neurogenesis which is a component of the extrinsic to plasma membrane, GPI-anchored; it is expressed in the adult (Malpighian tubule and ellipsoid body). It has been sequenced and its amino acid sequence contains an alkaline phosphatase family. It has been mapped cytologically to 100B1. There are 4 recorded alleles: 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult Malpighian tubule and are viable. Aph-4 is discussed in 13 references (excluding sequence accessions), dated between 1990 and 2003. These include at least one study of natural polymorphisms and 5 molecular studies. FB FBgn0016123
3764 aPKC ;aPKC-zeta;atypical protein kinase C;CG10261;DaPKC;i;l(2)k06403;pkc-3;PKCl;PKCl,i;pschur;psu atypical protein kinase C fruit fly Drosophila melanogaster The D. melanogaster gene atypical protein kinase C, abbreviated as aPKC, is reported here. It has also been known in FlyBase as CG10261 and l(2)k06403. It encodes a product with protein serine/threonine kinase activity involved in oocyte cell fate determination (sensu Insecta) which is a component of the apical cortex. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a protein kinase C-terminal domain, a phorbol esters/diacylglycerol binding domain and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 51D5--6. It interacts genetically with orb. There are 10 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 3 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ventral embryonic/first instar larval cuticle, the (with Df(2R)Jp1) embryonic/first instar larval cuticle, the embryonic head and 6 other listed tissues and are recessive lethal, embryonic (with Df(2R)Jp1) lethal and somatic clone cell polarity. aPKC is discussed in 74 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 5 molecular studies. Among findings on aPKC mutants, a loss of function mutation in aPKC results in loss of apico-basal polarity and multilayering of epithelia in the embryo. FB FBgn0022131
3767 Appl &bgr;-amyloid-protein-precursor-like;A&bgr;;Abeta;APP;appl;BcDNA:GH04413;beta-amyloid-protein-precursor-like;CG6666;CG7727;EG:65F1.5 β amyloid protein precursor-like fruit fly Drosophila melanogaster The D. melanogaster gene β amyloid protein precursor-like, abbreviated as Appl, is reported here. It has also been known in FlyBase as BcDNA:GH04413. It encodes a product with putative receptor activity involved in neurogenesis which is localized to the axon and the plasma membrane; it is expressed in the adult (Kenyon cell, adult brain, head, lobe of mushroom body and 2 other listed tissues), embryo (embryonic central nervous system, longitudinal connectives, peripheral nervous system, ventral nerve cord commissure and 2 other listed tissues), larva (axon, eye-antennal disc, larval brain, larval central nervous system and 7 other listed tissues) and prepupa and pupa (lamina, lobula, medulla neuropil, lamina and 4 other listed tissues). It has been sequenced and its amino acid sequence contains an amyloidogenic glycoprotein (Amyloid A4). It has been mapped by recombination to 1-0.0 and cytologically to 1B9--10. It interacts genetically with Khc and Sh. There are 17 recorded alleles: 12 in vitro constructs (none available from the public stock centers), 4 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the bouton and the larval nervous system and are visual behavior defective, viable, fertile and neuroanatomy defective. Appl is discussed in 52 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and 13 molecular studies. Among findings on Appl function, Appl promotes synapse differentiation at the neuromuscular junction. FB FBgn0000108
3769 apt 3041;CG5393;l(2)03041;l(2)06369;l(2)09049;l(2)59Ea;l(2)k11531;tdf;TDF/APT;Trachea defective;tracheae defective apontic fruit fly Drosophila melanogaster The D. melanogaster gene apontic, abbreviated as apt, is reported here. It has also been known in FlyBase as l(2)03041, l(2)06369, l(2)09049, l(2)k11531 and tdf. It encodes a product with RNA binding involved in negative regulation of oskar mRNA translation which is localized to the nucleus; it is expressed in the embryo (acron, amnioserosa, cardioblast, dorsal vessel primordium and 14 other listed tissues) and ovary (follicle cell, nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a myb DNA binding domain. It has been mapped cytologically to 59F1--4. It interacts genetically with Dfd and aret. There are 21 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 17 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the embryonic/larval trachea and are recessive lethal. apt is discussed in 57 references (excluding sequence accessions), dated between 1990 and 2003. These include at least 4 studies of mutant phenotypes, 2 studies of wild-type function and 8 molecular studies. Among findings on apt function, apt is required for morphogenesis and function of the heart. FB FBgn0015903
3773 ara ;CG10571;Iro;IRO-C;Iroquis complex;Iroquois;iroquois gene complex;iroquois-complex araucan fruit fly Drosophila melanogaster The D. melanogaster gene araucan, abbreviated as ara, is reported here. It has also been known in FlyBase as iro. It encodes a product with transcription factor activity involved in wing vein specification which is a component of the nucleus; it is expressed in the embryo (embryonic/larval proventriculus, epidermis and procephalic segment) and larva (alula, dorsal metathoracic disc, imaginal disc, larval ventral ganglion and 5 other listed tissues). It has been sequenced and its amino acid sequence contains a homeobox domain and an iroquois-class homeodomain protein motif. It has been mapped cytologically to 69C8--10. It interacts genetically with mirr, ph-d, Sce, Pc, Pcl and 9 other listed genes. There are 13 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 10 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the macrochaeta, the microchaeta, the mesothoracic segment and 4 other listed tissues and are viable, visible, recessive female sterile, recessive male sterile and (with ararF209) visible. ara is discussed in 93 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 7 studies of mutant phenotypes, 4 studies of wild-type function and 5 molecular studies. FB FBgn0015904
3774 aralar1 ;BcDNA:GH07418;CG2139;DmAralar fruit fly Drosophila melanogaster The D. melanogaster gene aralar1 is reported here. It has also been known in FlyBase as BcDNA:GH07418 and CG2139. It encodes a product with calcium ion binding involved in mitochondrial transport which is a component of the integral to membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a EF-hand family and a mitochondrial carrier domain. It has been mapped cytologically to 99F4--5. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. aralar1 is discussed in 16 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0028646
3776 Arc-p34 38C.47;anon-WO0118547.154;ARC-P34;Arpc2;ARPC2/p34;CG10954;p34 fruit fly Drosophila melanogaster The D. melanogaster gene Arc-p34 is reported here. It has also been known in FlyBase as CG10954. It encodes a product with actin binding involved in regulation of actin polymerization and/or depolymerization which is a component of the Arp2/3 protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 38C6. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Arc-p34 is discussed in 17 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one study of wild-type function and 5 molecular studies. FB FBgn0032859
3777 Arc105 ;BcDNA:GH03922;CG4184;dARC105;Med9/ARC105 fruit fly Drosophila melanogaster The D. melanogaster gene Arc105 is reported here. It has also been known in FlyBase as BcDNA:GH03922. It encodes a product with putative RNA polymerase II transcription mediator activity putatively involved in transcription initiation from Pol II promoter which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 21D1. There is one recorded allele, which is wild-type. Arc105 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027592
3778 Arc32 ;CG13867;CG30140;dARC32;Med8/ARC32 fruit fly Drosophila melanogaster The D. melanogaster gene Arc32 is reported here. It has also been known in FlyBase as CG13867. It encodes a product with putative RNA polymerase II transcription mediator activity putatively involved in transcription initiation from Pol II promoter which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 56F16. There is one recorded allele, which is wild-type. Arc32 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0034503
3779 Arc42 ;CG4703;dARC42 fruit fly Drosophila melanogaster The D. melanogaster gene Arc42 is reported here. It has also been known in FlyBase as CG4703. It encodes a product with acyl-CoA dehydrogenase activity (EC:1.3.99.3) putatively involved in transcription initiation from Pol II promoter which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence contains an acyl-CoA dehydrogenase. It has been mapped cytologically to 92B4. There is one recorded allele, which is wild-type. Arc42 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038742
3780 Arc70 ;CG1793;CG1823;dARC70 fruit fly Drosophila melanogaster The D. melanogaster gene Arc70 is reported here. It has also been known in FlyBase as CG1793 and CG1823. It encodes a product with putative RNA polymerase II transcription mediator activity putatively involved in transcription initiation from Pol II promoter which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 102C3. There is one recorded allele, which is wild-type. Arc70 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0039923
3781 Arc92 ;CG12254;dARC92;LD07688 fruit fly Drosophila melanogaster The D. melanogaster gene Arc92 is reported here. It has also been known in FlyBase as CG12254. It encodes a product with putative RNA polymerase II transcription mediator activity putatively involved in transcription initiation from Pol II promoter which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 92C1. There is one recorded allele, which is wild-type. Arc92 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0038760
3782 aret ;arrest;arrest/Bruno;BcDNA:GM15173;bru;Bruno;CG31762;CG6319;Dm Bru;ms(2)01284;NEST:bs01g04;NEST:bs34h11 arrest fruit fly Drosophila melanogaster The D. melanogaster gene arrest, abbreviated as aret, is reported here. It has also been known in FlyBase as BcDNA:GM15173, NEST:bs01g04 and bruno. It encodes a product with RNA binding involved in spermatid development which is expressed in the adult (testis) and ovary (germarium, nurse cell and oocyte). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 33D3--5. It interacts genetically with osk and apt. There are 13 recorded alleles: 1 in vitro construct (not available from the public stock centers), 11 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the oogonial cell and the egg chamber and are recessive female sterile. aret is discussed in 71 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 5 studies of mutant phenotypes, 4 studies of wild-type function and 7 molecular studies. Among findings on aret function, aret has a function in the cytoblast to cyst transition during early oogenesis. FB FBgn0000114
3788 arg ;arginase;CG18104;EG:171D11.4;EG:65F1.3 arginase fruit fly Drosophila melanogaster The D. melanogaster gene arginase, abbreviated as arg, is reported here. It has also been known in FlyBase as CG18104, EG:171D11.4, EG:65F1.3 and arginase. It encodes a product with arginase activity (EC:3.5.3.1) involved in arginine catabolism to ornithine which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an arginase family. It has been mapped cytologically to 1B7--8. There are 9 recorded alleles: 8 classical mutants (4 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are fertile and viable. arg is discussed in 12 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 4 molecular studies. FB FBgn0023535
3790 argos Aos;aos: argos;arg;Calcineurin suppressor, chromosome 3, group 3;CG1921;CG4531;CS3-3;dSprouty;dSPRY;giant lens;gil;l(3)05845;l(3)05959;l(3)j5E11;l(3)rJ472;l(3)rJ812;l(3)rQ526;rlt;roulette;sprouty;Spry;Sry;strawberry;sty argos fruit fly Drosophila melanogaster The D. melanogaster gene argos is reported here. It has also been known in FlyBase as gil, l(3)05959 and rlt. It encodes a product with receptor antagonist activity involved in negative regulation of cell fate which is localized to the extracellular; it is expressed in the embryo (epidermis and midline glial cell) and larva (eye-antennal disc). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 73A2. It interacts genetically with ed, S, sty, bul, cln and 28 other listed genes. There are 65 recorded alleles: 30 in vitro constructs (1 available from the public stock centers), 34 classical mutants (4 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the somatic clone eye, the somatic clone photoreceptor cell R1 to 6, the embryonic head and 30 other listed tissues and are embryonic recessive lethal, embryonic (with Df(3L)st-g18) lethal, (with Df(3L)st-k7) lethal, (with Df(3L)st-f13) lethal, (with argos5F4) cell polarity, (with argosA254δ15) cell polarity and (with argosrlt) cell polarity. argos is discussed in 244 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 30 studies of mutant phenotypes, 17 studies of wild-type function and 11 molecular studies. Among findings on argos mutants, argos mutants act on the development of lamina cells preventing the correct differentiation of the target region of photoreceptor axons and therefore leading to an axon guidance phenotype. Among findings on argos function, argos mediate the number of bracts per mechanosensory bristle in the leg by lateral inhibition. (However, there is much more information on function so that may not be representative.) FB FBgn0004569
3794 arm &bgr;-cat;&Bgr;-catenin;ARM;Armadillo;b-catenin;beta-catenin;catenin;CG11579;EG:86E4.6;l(1)2Bv;l(1)arm;l(1)G0192;l(1)G0234;l(1)G0410;t12687 ALR Dm armadillo fruit fly Drosophila melanogaster The D. melanogaster gene armadillo, abbreviated as arm, is reported here. It has also been known in FlyBase as l(1)G0192, l(1)G0234 and l(1)G0410. It encodes a product with alpha-catenin binding involved in segment polarity determination which is localized to the cell-cell adherens junction, the intercellular junction and the plasma membrane; it is expressed in the adult (head), embryo (Malpighian tubule, antennal segment, axon, embryonic central nervous system and 22 other listed tissues), larva (embryonic/larval digestive system, embryonic/larval salivary gland, eye-antennal disc, imaginal disc and 5 other listed tissues) and ovary (follicle cell, nurse cell and oocyte). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-1.2 and cytologically to 2B14. It interacts genetically with pan, shg, wg, nkd, sgg and 49 other listed genes. There are 137 recorded alleles: 76 in vitro constructs (2 available from the public stock centers), 60 classical mutants (4 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic somatic clone cell autonomous segment, the embryonic head, the dorsal embryonic epidermis and 19 other listed tissues and are embryonic segment polarity recessive lethal. arm is discussed in 769 references (excluding sequence accessions), dated between 1982 and 2004. These include at least 69 studies of mutant phenotypes, 11 studies of wild-type function and 25 molecular studies. Among findings on arm mutants, arm mutants display mirror image duplication of denticle belts. Among findings on arm function, arm does not play a general role in inhibiting cell migration or process extension. FB FBgn0000117
3796 Arp11 ARP11;CG12235 fruit fly Drosophila melanogaster The D. melanogaster gene Arp11 is reported here. It has also been known in FlyBase as CG12235. It encodes a product with actin binding involved in cytoskeleton organization and biogenesis which is a component of the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18D12. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. Arp11 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031050
3797 Arp14D Actr14D;ARP14D;ARP2;CG9901 Actin-related protein 14D fruit fly Drosophila melanogaster The D. melanogaster gene Actin-related protein 14D, abbreviated as Arp14D, is reported here. It has also been known in FlyBase as Actr14D. It encodes a product with actin binding involved in cytoskeleton organization and biogenesis which is a component of the Arp2/3 protein complex; it is expressed in the embryo (embryonic central nervous system, embryonic/larval hindgut and embryonic/larval proventriculus). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 14E1. There is one recorded allele, which is wild-type. Arp14D is discussed in 17 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 molecular studies. FB FBgn0011742
3798 Arp53D Actr53D;arp5;ARP53D;CG5409 Actin-related protein 53D fruit fly Drosophila melanogaster The D. melanogaster gene Actin-related protein 53D, abbreviated as Arp53D, is reported here. It has also been known in FlyBase as Actr53D. It encodes a product with putative structural constituent of cytoskeleton involved in cytoskeleton organization and biogenesis which is a component of the actin cytoskeleton; it is expressed in the adult (testis). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 53C15. There is one recorded allele, which is wild-type. Arp53D is discussed in 13 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 5 molecular studies. FB FBgn0011743
3799 Arp66B Actin-related protein;AcTr66B;anon-WO0172774.138;ARP3;CG7558 Actin-related protein 66B fruit fly Drosophila melanogaster The D. melanogaster gene Actin-related protein 66B, abbreviated as Arp66B, is reported here. It has also been known in FlyBase as Actr66B. It encodes a product with actin binding involved in cell cycle dependent actin filament reorganization which is a component of the Arp2/3 protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 66B6. It interacts genetically with Sop2. There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the germ-line clone nurse cell, the germ-line clone oocyte, the germ-line clone nurse cell ring canal and 3 other listed tissues and are pharate adult recessive lethal. Arp66B is discussed in 28 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 3 molecular studies. FB FBgn0011744
3800 Arp87C Actr87C;Arp;Arp-1;ARP1;ARP87C;CG6174;gdl;grid;gridlock Actin-related protein 87C fruit fly Drosophila melanogaster The D. melanogaster gene Actin-related protein 87C, abbreviated as Arp87C, is reported here. It has also been known in FlyBase as Actr87C and grid. It encodes a product with actin binding involved in cytoskeleton organization and biogenesis which is a component of the dynactin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 87C5. It interacts genetically with CycB. There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Arp87C is discussed in 24 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. FB FBgn0011745
3802 Arr1 3H10;Arr;ArrA;ArrA: Arrestin A;arrestin;Arrestin A;arrestin1;CG5711;DA;DmArr1;Dmarrestin;Drosophila Arrestin;DS-Ag;FBgn0000120;Phosrestin-II;PRII Arrestin 1 fruit fly Drosophila melanogaster The D. melanogaster gene Arrestin 1, abbreviated as Arr1, is reported here. It encodes a product with metarhodopsin binding involved in metarhodopsin inactivation which is a component of the membrane fraction; it is expressed in the adult (photoreceptor cell, rhabdomere and testis). It has been sequenced and its amino acid sequence contains an arrestin. It has been mapped cytologically to 36E3. It interacts genetically with Arr2. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which are dominant olfaction defective and (with Df(2L)II30) olfaction defective. Arr1 is discussed in 46 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 2 studies of mutant phenotypes, 6 studies of wild-type function and 9 molecular studies. FB FBgn0000120
3803 Arr2 &Bgr;-Arrestin;49;49kD Arrestin homolog;AH;arr2;ArrB;ArrB-ml;ArrB: Arrestin B;arrestin;Arrestin B;arrestin-2;arrestin-like protein;arrestin2;Beta-Arrestin;CG5962;Phosrestin I;phosrestin-1;PRI Arrestin 2 fruit fly Drosophila melanogaster The D. melanogaster gene Arrestin 2, abbreviated as Arr2, is reported here. It encodes a product with metarhodopsin binding involved in deactivation of rhodopsin mediated signaling which is a component of the membrane fraction; it is expressed in the adult (rhabdomere). It has been sequenced and its amino acid sequence contains an arrestin. It has been mapped cytologically to 66D9. It interacts genetically with norpA, Arr1, rdgB, CDase and lace. There are 18 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 11 classical mutants (none available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the photoreceptor cell, the retina and the rhabdomere and are neurophysiology defective. Arr2 is discussed in 64 references (excluding sequence accessions), dated between 1982 and 2003. These include at least 4 studies of mutant phenotypes, 7 studies of wild-type function and 10 molecular studies. FB FBgn0000121
3807 ase AS-C T8;AS-C T8ase;AS-T8;ASC;ascT8;Asense;CG3258;EG:165H7.2;sc/T8;T1;T1a;T8 asense fruit fly Drosophila melanogaster The D. melanogaster gene asense, abbreviated as ase, is reported here. It encodes a product with DNA binding involved in neurogenesis which is localized to the nucleus; it is expressed in the embryo (embryonic central nervous system, embryonic ganglion mother cell, embryonic peripheral nervous system, embryonic/larval midgut and 11 other listed tissues) and larva (antennal disc, dorsal mesothoracic disc, eye disc, ganglion mother cell and 9 other listed tissues). It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain and a myc-type, helix-loop-helix dimerization domain. It has been mapped by recombination to 1-0.0 and cytologically to 1B3. It interacts genetically with esg and amos. There are 14 recorded alleles: 12 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. ase is discussed in 153 references (excluding sequence accessions), dated between 1929 and 2003. These include at least 6 studies of mutant phenotypes, 3 studies of wild-type function, 2 studies of natural polymorphisms and 10 molecular studies. Among findings on ase mutants, defects due to ase mutations are enhanced by the haploid condition of other genes of the ASC, and can be corrected by an ase transgene. Among findings on ase function, ase may be a neural precursor gene, rather than a proneural gene. FB FBgn0000137
3808 asf1 ASF1;CG9383;dASF1 anti-silencing factor 1 fruit fly Drosophila melanogaster The D. melanogaster gene anti-silencing factor 1, abbreviated as asf1, is reported here. It encodes a product with putative chromatin binding involved in regulation of cell cycle which is a component of the RCAF complex. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-46.2 and cytologically to 76B9. It interacts genetically with tlk. There are 4 recorded alleles: 1 in vitro construct (not available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the germ-line clone ovary and are germ-line clone female sterile and larval (with Df(3L)kto2) lethal. asf1 is discussed in 14 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 studies of mutant phenotypes, 2 studies of wild-type function and 2 molecular studies. Among findings on asf1 mutants, mutations in asf1 de-repress silencing at heterochromatin. FB FBgn0029094
3809 ash1 ash;ash-1;CG8887;dash;dash: discs absent;discs absent;discs absent, small, or homeotic;l(3)SG29a;or homeotic;small absent, small, or homeotic discs 1 fruit fly Drosophila melanogaster The D. melanogaster gene absent, small, or homeotic discs 1, abbreviated as ash1, is reported here. It encodes a product with histone lysine N-methyltransferase activity (H3-K4 specific) involved in oogenesis (sensu Insecta) which is a component of the nucleus; it is expressed in the larva (imaginal disc) and ovary (nurse cell). It has been sequenced and its amino acid sequence contains a BAH (bromo-adjacent homology) domain and a PHD-finger. It has been mapped by recombination to 3-46.6 and cytologically to 76B8--9. It interacts genetically with E(z), brm, trx, fs(1)h, Scr and 26 other listed genes. There are 37 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 33 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the wing and are pharate adult recessive lethal and homeotic visible. ash1 is discussed in 80 references (excluding sequence accessions), dated between 1971 and 2003. These include at least 17 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies. Among findings on ash1 mutants, ash1 mutant larvae may have small or absent imaginal discs or express homeotic transformations. Among findings on ash1 function, ash1 is one of the trithorax group of genes. FB FBgn0005386
3810 ash2 1124/11;291.8;703;ash-2;CG6677;l(3)112411;l(3)S112411;l(3)SG65;mad;mad: many abnormal discs;many abnormal discs absent, small, or homeotic discs 2 fruit fly Drosophila melanogaster The D. melanogaster gene absent, small, or homeotic discs 2, abbreviated as ash2, is reported here. It has also been known in FlyBase as l(3)S112411. It encodes a product with putative transcription regulator activity involved in wing morphogenesis which is localized to the nucleus; it is expressed in the larva (embryonic/larval fat body, embryonic/larval salivary gland and imaginal disc). It has been sequenced and its amino acid sequence contains a PHD-finger. It has been mapped by recombination to 3-78.6 and cytologically to 96A13. It interacts genetically with fs(1)h, ph-p, Ubx, Antp, E(z) and 2 other listed genes. There are 24 recorded alleles: 23 classical mutants (1 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the (with ash29) metathoracic leg, the proboscis, the antenna and 5 other listed tissues and are larval recessive lethal. ash2 is discussed in 47 references (excluding sequence accessions), dated between 1971 and 2003. These include at least 7 studies of mutant phenotypes, one study of wild-type function and 6 molecular studies. Among findings on ash2 mutants, mutations in ash2 give rise to homeotic transformations. Among findings on ash2 function, ash2 has a role in wing development. FB FBgn0000139
3812 asp anon-96Aa;anon-WO0118547.279;Asp;CG6875 abnormal spindle fruit fly Drosophila melanogaster The D. melanogaster gene abnormal spindle, abbreviated as asp, is reported here. It has also been known in FlyBase as anon-96Aa. It encodes a product with microtubule binding putatively involved in microtubule-based process which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-85.2 and cytologically to 96A19--20. It interacts genetically with mgr, cleo, Dsor1, rl, polo and 6 other listed genes. There are 18 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 15 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the imaginal disc, the wing, the eye and 4 other listed tissues and are recessive semi-lethal, recessive conditional cs male sterile, recessive female sterile, recessive meiotic, recessive mitotic, recessive lethal, recessive visible and cytokinesis defective. asp is discussed in 66 references (excluding sequence accessions), dated between 1985 and 2003. These include at least 10 studies of mutant phenotypes, 2 studies of wild-type function and 4 molecular studies. Among findings on asp mutants, immunocytological techniques have been used to observe the spindle apparatus in asp mutants and the results indicate that non-disjunction in asp can result from the association of condensed chromosomes with hemi-spindle structures in meiosis and mitosis. Among findings on asp function, asp may play a role in spindle pole organization during mitosis. FB FBgn0000140
3816 Asx ;CG8787 Additional sex combs fruit fly Drosophila melanogaster The D. melanogaster gene Additional sex combs, abbreviated as Asx, is reported here. It encodes a product with transcriptional repressor activity involved in chromatin silencing which is localized to the polytene chromosome; it is expressed in the embryo (central nervous system and neurectoderm) and ovary (nurse cell). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-72 and cytologically to 51A5--6. It interacts genetically with Pc, sxc, brm, trx, ph-d and 15 other listed genes. There are 27 recorded alleles: 26 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the abdominal tergite 5 to 6, the haltere and the adult abdominal segment 3 to 4 and are viable and homeotic visible. Asx is discussed in 78 references (excluding sequence accessions), dated between 1984 and 2003. These include at least 18 studies of mutant phenotypes, 6 studies of wild-type function and 4 molecular studies. Among findings on Asx function, Asx is required for both the activation and repression of homeotic loci. FB FBgn0000142
3820 ato ;ato1;CG7508 atonal fruit fly Drosophila melanogaster The D. melanogaster gene atonal, abbreviated as ato, is reported here. It encodes a product with DNA binding involved in cell fate commitment which is a component of the nucleus; it is expressed in the embryo (P cell, chordotonal organ and external sensory organ) and larva (Johnston's organ, chordotonal organ, chordotonal organ of scabellum, chordotonal organ of tegula and 6 other listed tissues). It has been sequenced and its amino acid sequence contains a REV protein (anti-repression trans-activator protein) and a helix-loop-helix dimerization domain. It has been mapped cytologically to 84F6. It interacts genetically with da, amos, ro, N, Dl and 14 other listed genes. There are 17 recorded alleles: 10 in vitro constructs (none available from the public stock centers), 6 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the eye, the ocellus, the interommatidial bristle and 39 other listed tissues and are visual behavior defective, recessive visible, recessive semi-lethal, recessive behavioral, (with Df(3R)p13) visible, neuroanatomy defective, (with ato2) visible, auditory system defective, neurophysiology defective, song defective and (with Df(3R)p13) neuroanatomy defective. ato is discussed in 242 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 21 studies of mutant phenotypes, 7 studies of wild-type function and 5 molecular studies. Among findings on ato function, ato is sufficient for specification of coeloconic sensilla in the antenna. FB FBgn0010433
3821 Atpα ;&agr;-subunit of ATPase;alpha-subunit of ATPase;Atp a;Atp&agr;;ATPa;ATPalpha;ATPase &agr; subunit;ATPase alpha subunit;ATPBagr;CG5670;Da-47;JY;K-ATPase;K-ATPase alpha subunit;K[+]-ATPase alpha-subunit;l(3)01164;l(3)01453;l(3)04492;l(3)j3B2;l(3)j3B7;l(3)j6A4;l(3)rM454;l(3)ry136;Na;Na+,K+ ATPase alpha-subunit.;Na+-K+-ATPase;Na+/K+ ATPase alpha subunit;Na,K ATPase;Na,K ATPase &agr; subunit;Na,K-ATPase;Na,K-ATPase &agr; subunit;Na-p;Na/K-ATPase;Na/K-ATPase &agr;-subunit;Na/K-ATPase alpha-subunit;Na+, K+ -ATPase;Na+,K+-ATPase;Na+,K+-ATPase &agr; subunit;Na+,K+-ATPase &agr;-subunit;Na+-K+-ATPase &agr;5-subunit;Na+-K+-ATPase &agr;5<\down>-subunit;Na+/K+ ATPase;Na+/K+-ATPase;Na+/K+ATPase;Na+K+ATPase;NaK ATPase;Na[+];sodium/potassium transporting ATPase alpha Na pump α subunit fruit fly Drosophila melanogaster The D. melanogaster gene Na pump α subunit, abbreviated as Atpα, is reported here. It has also been known in FlyBase as CG5670, l(3)01453, l(3)04492 and l(3)ry136. It encodes a product with sodium/potassium-exchanging ATPase activity (EC:3.6.3.9) involved in tracheal system development (sensu Insecta) which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains a na+,K+ ATPase β subunit, a H+/K+ and Na+/K+ transporting ATPase, a haloacid dehalogenase/epoxide hydrolase family and a E1-E2 ATPases. It has been mapped cytologically to 93A4--B2. There are 35 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 30 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic cuticle and the embryonic segment and are embryonic recessive lethal. Atpα is discussed in 69 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 2 studies of mutant phenotypes and 5 molecular studies. FB FBgn0002921
3823 ATPsyn-β &bgr;-ATPase;ATP;ATP synthase beta;ATP synthase beta subunit;ATPB;ATPsyn b;ATPsyn-&bgr;;ATPsyn-b;ATPsyn-beta;beta-ATPase;CG11154;CG8189;F1ATP synthase;Fo-ATP synthase subunit b;H+-ATPase beta subunit ATP synthase-β fruit fly Drosophila melanogaster The D. melanogaster gene ATP synthase-β, abbreviated as ATPsyn-β, is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ATP synthase α and β subunit, N-terminal and a ATP synthase α and β subunit, C-terminal. It has been mapped cytologically to 102D1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. ATPsyn-β is discussed in 24 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 3 studies of mutant phenotypes and 3 molecular studies. FB FBgn0010217
3824 ATPsyn-γ ATP synthase subunit gamma.;ATPsyn-&ggr;;ATPsyn-gamma;CG7610;F1ATP synthase ATP synthase-γ chain fruit fly Drosophila melanogaster The D. melanogaster gene ATP synthase-γ chain, abbreviated as ATPsyn-γ, is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ATP synthase γ subunit. It has been mapped cytologically to 99B10. There is one recorded allele, which is wild-type. ATPsyn-γ is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0020235
3825 ATPsyn-b ;CG8189;Fo-ATP synthase subunit b ATP synthase, subunit b fruit fly Drosophila melanogaster The D. melanogaster gene ATP synthase, subunit b, abbreviated as ATPsyn-b, is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 67C5. There is one recorded allele, which is wild-type. ATPsyn-b is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0019644
3826 ATPsyn-Cf6 ;BcDNA:RH08870;CG4412 ATPase coupling factor 6 fruit fly Drosophila melanogaster The D. melanogaster gene ATPase coupling factor 6, abbreviated as ATPsyn-Cf6, is reported here. It has also been known in FlyBase as BcDNA:RH08870. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase, central stalk (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 94E13. There is one recorded allele, which is wild-type. ATPsyn-Cf6 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 4 molecular studies. FB FBgn0016119
3827 ATPsyn-d ATP synthase chain D;ATPase synthase;ATPase synthase, subunit d;CG6030;subunit d ATP synthase, subunit d fruit fly Drosophila melanogaster The D. melanogaster gene ATP synthase, subunit d, abbreviated as ATPsyn-d, is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 91F1. There is one recorded allele, which is wild-type. ATPsyn-d is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0016120
3828 att alternative testis transcripts;att-ORFA;CG4241 alternative testis transcripts fruit fly Drosophila melanogaster The D. melanogaster gene cassette alternative testis transcripts, abbreviated as att, is reported here. It has also been known in FlyBase as CG4241. It encodes a product which is expressed in the adult (testis). It has been sequenced. It has been mapped cytologically to 92F1. There is one recorded allele, which is wild-type. att is discussed in 6 references (excluding sequence accessions), dated between 1996 and 2004. These include at least one molecular study. FB FBgn0019839
3834 aub anon-WO0118547.388;CG10522;CG6137;cit;CITRON;citron kinase;dck;Drosophila citron kinase;l(3)7m-62;l(3)7m62;l(3)SG21;ms(2)32D;stellate-interacting gene;sti;sting aubergine fruit fly Drosophila melanogaster The D. melanogaster gene aubergine, abbreviated as aub, is reported here. It has also been known in FlyBase as ms(2)32D and sting. It encodes a product involved in oogenesis (sensu Insecta) which is a component of the polar granule; it is expressed in the adult (ovary and testic). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-39 and cytologically to 32C5. It interacts genetically with osk. There are 18 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 13 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the posterior maternal effect embryo and are female sterile and maternal effect recessive lethal. aub is discussed in 46 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 4 studies of mutant phenotypes, 2 studies of wild-type function and 7 molecular studies. Among findings on aub mutants, mutations at the aub locus cause defects in midoogenesis. Among findings on aub function, aub is required for dorso-ventral patterning and posterior body patterning. FB FBgn0000146
3835 aur 87A7-9/1;87A7-9/2;A-type Aurora kinase;aurA;aurora A;Aurora A kinase;aurora-A;auroraA;CG3068;ck10;ck10;ck[10];early-A;fruhe2;l(3)87Ac;l(3)ck10 aurora fruit fly Drosophila melanogaster The D. melanogaster gene aurora, abbreviated as aur, is reported here. It encodes a product with protein kinase activity (EC:2.7.1.37) involved in protein amino acid phosphorylation which is a component of the centrosome. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a tyrosine kinase catalytic domain and a serine/Threonine protein kinase family active site. It has been mapped by recombination to 3-53 and cytologically to 87A3. It interacts genetically with E(z) and bora. There are 18 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 11 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the (with aur37) thecogen cell, the (with aur37) eo neuron, the ectopic (with aur37) trichogen cell and the ectopic (with aur37) tormogen cell and are pupal recessive lethal, (with aur87Ac-5) mitotic, (with aur3) female sterile and pupal (with aur37) lethal. aur is discussed in 42 references (excluding sequence accessions), dated between 1981 and 2003. These include at least 4 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. FB FBgn0000147
3838 awd 1084/08;anon-EST:Liang-2.27;anon-EST:Liang-2.28;anon-WO0172774.80;anon-WO0172774.82;BcDNA:GM19775;BcDNA:RH27794;CG2210;clone 2.27;clone 2.28;e(shi)A;eshiA;K-pn;K-pn: Killer of prune;killer of prune;Killer-of-prune;Kpn;l(3)j2A4;l(3)L8700;NDKB;NDP kinase;NDPK;nucleoside diphosphate kinase abnormal wing discs fruit fly Drosophila melanogaster The D. melanogaster gene abnormal wing discs, abbreviated as awd, is reported here. It has also been known in FlyBase as BcDNA:GM19775, BcDNA:RH27794, l(3)L8700 and l(3)j2A4. It encodes a product with nucleoside-diphosphate kinase activity (EC:2.7.4.6) involved in GTP biosynthesis which is localized to the microtubule; it is expressed in the larva (dorsal mesothoracic disc). It has been sequenced and its amino acid sequence contains a nucleoside diphosphate kinase. It has been mapped cytologically to 100D2. It interacts genetically with pn, shi, hop and btl. There are 49 recorded alleles: 7 in vitro constructs (none available from the public stock centers), 41 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the conditional ts (with awdMSM95) photoreceptor cell and the conditional ts (with awdMSM95) optic cartridge and are pupal recessive lethal and conditional ts (with awdMSM95) paralytic. awd is discussed in 82 references (excluding sequence accessions), dated between 1955 and 2003. These include at least 8 studies of mutant phenotypes, 5 studies of wild-type function and 14 molecular studies. Among findings on awd mutants, an altered awd NDP kinase activity is involved in the mechanisms underlying the conditional lethality of the awdK mutation. Among findings on awd function, there is an embryonic requirement for maternal germline awd expression, but the amount required is quite low. FB FBgn0000150
3839 Awh arrowhead;CG1072;l(3)63Ea;l(3)63Ea/Awh;l(3)63Ea: lethal(3)63Ea;l(3)64Ea;l(3)SH9;l63Ea;lethal(3)63Ea Arrowhead fruit fly Drosophila melanogaster The D. melanogaster gene Arrowhead, abbreviated as Awh, is reported here. It has also been known in FlyBase as l(3)63Ea. It encodes a product with transcription factor activity putatively involved in ectoderm development which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 63F4. There are 32 recorded alleles: 1 in vitro construct (not available from the public stock centers), 30 classical mutants (3 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the eye and the (with Awh12) salivary gland imaginal ring and are recessive lethal and visible. Awh is discussed in 25 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one study of wild-type function and one molecular study. Among findings on Awh function, Awh is necessary for establishment of proper numbers of cells within a subset of imaginal precursor tissues. FB FBgn0013751
3843 Axs Aberrant X segregation;CG9703 Abnormal X segregation fruit fly Drosophila melanogaster The D. melanogaster gene Abnormal X segregation, abbreviated as Axs, is reported here. It encodes a product involved in female meiosis chromosome segregation. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-56 and cytologically to 15A1. It interacts genetically with ald and lwr. There are 12 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 5 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the female meiotic chromosome and are semidominant meiotic. Axs is discussed in 24 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 3 studies of mutant phenotypes and 4 molecular studies. Among findings on Axs mutants, examination of meiotic prophase in Axs mutants reveals that while heterochromatic pairing may be a component of the mechanism of homologous segregation, it is not sufficient to guarantee proper disjunction of nonexchange homologs. FB FBgn0000152
3846 B anon-EST:Liang-1.69;anon-EST:Posey92;bar;Bar eye;BarH1;BB;BB: double Bar;clone 1.69;female-specific lethal on X;flex;InfraBar;ITS1;l(1)20Fa;NO;rDNA;rDNA repeat;rDNA unit;ribosomal RNA;rRNA;small nuclear RNA a;snRNA-a;Ultrabar;Xbb Bar fruit fly Drosophila melanogaster The D. melanogaster gene Bar, abbreviated as B, is reported here. It encodes a product involved in bristle morphogenesis. It has been mapped by recombination to 1-57.0 and cytologically to 16A1+. It interacts genetically with oro, dpp, mb, Ble, su(B) and 9 other listed genes. There are 71 recorded alleles: 70 classical mutants (10 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ommatidium and the eye and are dominant visible and viable. B is discussed in 159 references, dated between 1914 and 2003. These include at least 35 studies of mutant phenotypes, one study of wild-type function and one molecular study. Among findings on B mutants, eyes of female heterozygous for a deficiency for B and a normal X are normal. FB FBgn0000154
3847 B-H1 ;Bar;Bar H1;Bar-H1;barh1;BarHI;BH1;CG5529 BarH1 fruit fly Drosophila melanogaster The D. melanogaster gene BarH1, abbreviated as B-H1, is reported here. It encodes a product with DNA binding involved in eye pigment granule morphogenesis (sensu Drosophila) which is a component of the nucleus; it is expressed in the embryo (embryonic central nervous system, external sensory organ, neuron, peripheral nervous system and thecogen cell) and larva (photoreceptor cell R6). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 16A5. It interacts genetically with Egfr, N, Ras85D, Sos, aop and 5 other listed genes. There are 9 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 4 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the (with Df(1)B) tarsal segment 3 to 5 and are (with Df(1)B) visible. B-H1 is discussed in 69 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 5 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies. FB FBgn0011758
3848 B-H2 B;Bar;Bar-H2;BarH2;BH2;CG5488 BarH2 fruit fly Drosophila melanogaster The D. melanogaster gene BarH2, abbreviated as B-H2, is reported here. It encodes a product with DNA binding involved in eye pigment granule morphogenesis (sensu Drosophila) which is a component of the nucleus; it is expressed in the embryo (embryonic central nervous system, external sensory organ, neuron, peripheral nervous system and thecogen cell), larva (photoreceptor cell R6) and prepupa and pupa (primary pigment cell). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 1-56.7 and cytologically to 16A1. There are 7 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 3 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the tarsal segment 3 to 5 and are recessive visible. B-H2 is discussed in 44 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and 4 molecular studies. FB FBgn0004854
3850 B52 ;B52/dSRp55;CG10851;dSRp55;E(Dfd);E(Dfd): Enhancer of Deformed;E726;Enhancer of Deformed;l(3)s2249;MabB52;MabB52: Monoclonal-antibody-B52;Monoclonal-antibody-B52;Rbp8;RNA-binding protein 8;rrm8;RSp55;serine-arginine protein 55;Serine/arginine rich protein 55;SR55;SR55: serine-arginine protein 55;SRp55;SRp55: Serine/arginine rich protein 55;Su(rst)B52 fruit fly Drosophila melanogaster The D. melanogaster gene B52 is reported here. It has also been known in FlyBase as E(Dfd), Rbp8 and l(3)s2249. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is localized to the polytene chromosome. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped by recombination to 3-52 and cytologically to 87F4--11. It interacts genetically with w, tub, tra2 and Rsf1. There are 15 recorded alleles: 7 in vitro constructs (none available from the public stock centers), 7 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the pigment cell and are recessive lethal and eye color defective. B52 is discussed in 56 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 11 studies of mutant phenotypes, one study of wild-type function and 9 molecular studies. Among findings on B52 function, B52 has a role in pre-mRNA splicing. FB FBgn0004587
3852 bab1 anon-WO0118547.639;bab;bab-I;BAB1;bric a brac;bric a brac I;bric-a-brac;CG13910;CG9097 bric a brac 1 fruit fly Drosophila melanogaster The D. melanogaster gene bric a brac 1, abbreviated as bab1, is reported here. It has also been known in FlyBase as CG13910 and bab. It encodes a product with transcription factor activity involved in sex differentiation which is localized to the nuclear; it is expressed in the larva (eye-antennal disc, ventral thoracic disc and ventral thoracic disc) and prepupa and pupa (tarsal segment). It has been sequenced and its amino acid sequence contains a BTB/POZ domain. It has been mapped cytologically to 61E2--F1. It interacts genetically with abd-A and Abd-B. There are 21 recorded alleles: 1 in vitro construct (available from the public stock centers), 19 classical mutants (3 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the terminal filament, the ovary, the germarium and 2 other listed tissues and are recessive female sterile and female recessive body color defective. bab1 is discussed in 71 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 5 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies. Among findings on bab1 function, bab1 integrates regulatory inputs from the homeotic and sex-determination pathways to control sexually dimorphic abdominal pigmentation and segment morphology. FB FBgn0004870
3853 bab2 bab;bab-II;BAB2;bric a brac;bric a brac II;bric-a-brac;bric-a-brac2;BTB-II;BTB-protein-II;BtbII;CG13911;CG9102 fruit fly Drosophila melanogaster The D. melanogaster gene bab2 is reported here. It has also been known in FlyBase as BtbII, CG13911 and bab-II. It encodes a product with transcription factor activity involved in female gonad development which is a component of the polytene chromosome. It has been sequenced and its amino acid sequence contains a BTB/POZ domain. It has been mapped cytologically to 61F2--3. It interacts genetically with abd-A and Abd-B. There are 14 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 11 classical mutants (none available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the ovary, the leg, the antenna and 3 other listed tissues and are recessive female sterile, recessive visible and female recessive body color defective. bab2 is discussed in 33 references (excluding sequence accessions), dated between 1993 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 2 molecular studies. FB FBgn0025525
3854 babo Activin A receptor 45A;Atf1;ATR-1;ATR-I;Atr45A;Atr45A: Activin A receptor 45A;AtrI;Bab;CG8224;G protein-coupled receptor kinase 3;Gprk-3;Gprk3;l(2)44Fd;l(2)k16912;STK-E baboon fruit fly Drosophila melanogaster The D. melanogaster gene baboon, abbreviated as babo, is reported here. It has also been known in FlyBase as Atr45A, Gprk3, l(2)44Fd and l(2)k16912. It encodes a product with activin binding involved in protein amino acid phosphorylation which is a component of the plasma membrane; it is expressed in the larva (imaginal disc) and ovary (nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a TGF-β receptor family, extracellular domain/Activin types I and II receptor domain, an eukaryotic protein kinase, a serine/Threonine protein kinase family active site and a GS motif preceding kinase domain in TGF β receptor. It has been mapped cytologically to 44F11--12. It interacts genetically with smo, ptc and EcR. There are 19 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 14 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the larva, the anal pad, the embryonic/larval anterior spiracle and 5 other listed tissues and are recessive lethal. babo is discussed in 52 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 5 studies of mutant phenotypes, 3 studies of wild-type function and 7 molecular studies. Among findings on babo mutants, null mutations and germ line clone analysis demonstrate that babo is not required during embryogenesis but is essential for proper pupation and adult viability. Among findings on babo function, babo primarily regulates cell proliferation and has only minimal effects on patterning. FB FBgn0011300
3856 Baldspot ;BcDNA:RE11908;blp;CG3971;CG5268;l(3)01618;l(3)02281;l(3)neo21;l(3)neo22;NEST:bs18f10;NEST:bs18g10;noa fruit fly Drosophila melanogaster The D. melanogaster gene Baldspot is reported here. It has also been known in FlyBase as CG3971, l(3)neo21 and l(3)neo22. It encodes a product which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 73B5. There are 14 recorded alleles: 13 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. Baldspot is discussed in 13 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 3 molecular studies. FB FBgn0036650
3859 bap &bgr;-adaptin;&bgr;1/2;AP-&bgr;1;AP-2&bgr;;BAD1;Beta Adaptin Drosophila 1;bgp;cg12532;CG7902;dNK-3;NK-3;NK3 bagpipe fruit fly Drosophila melanogaster The D. melanogaster gene bagpipe, abbreviated as bap, is reported here. It encodes a product with DNA binding involved in mesoderm cell fate specification which is a component of the nucleus; it is expressed in the embryo (mesoderm, visceral mesoderm and cardioblast). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors and a homeobox domain. It has been mapped cytologically to 93D10. There are 6 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the midgut muscle and the embryonic larval midgut and are lethal. bap is discussed in 98 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 3 studies of mutant phenotypes and 8 molecular studies. FB FBgn0004862
3860 Bap &bgr;-adaptin;&bgr;1/2;AP-&bgr;1;AP-2&bgr;;AP-2beta;AP-beta1;BAD1;Beta Adaptin Drosophila 1;beta-adaptin;beta1/2;bgp;CG12532;CG7902;dNK-3;nk-3;NK3 Beta Adaptin fruit fly Drosophila melanogaster The D. melanogaster gene &Bgr; Adaptin, abbreviated as Bap, is reported here. It encodes a product involved in synaptic vesicle coating which is localized to the coated pit. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18E4--5. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. Bap is discussed in 23 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of natural polymorphisms and 3 molecular studies. FB FBgn0010380
3861 Bap55 BAP55;BRM-associated protein 55;CG6546 Brahma associated protein 55kD fruit fly Drosophila melanogaster The D. melanogaster gene Brahma associated protein 55kD, abbreviated as Bap55, is reported here. It has also been known in FlyBase as BAP55 and CG6546. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is putatively a component of the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 54B13. There is one recorded allele, which is wild-type. Bap55 is discussed in 14 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 3 molecular studies. FB FBgn0025716
3862 Bap60 BAP60;BAPp60;brahma associated protein 60 kDa;BRM-associated protein 60;CG4303;i127;i133 Brahma associated protein 60kD fruit fly Drosophila melanogaster The D. melanogaster gene Brahma associated protein 60kD, abbreviated as Bap60, is reported here. It has also been known in FlyBase as BAP60 and BAP62. It encodes a product with general RNA polymerase II transcription factor activity putatively involved in chromatin assembly/disassembly which is a component of the nucleosome remodeling complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 11E1. There is one recorded allele, which is wild-type. Bap60 is discussed in 16 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 4 molecular studies. FB FBgn0025463
3863 barr 38B.3;barren;CAP-H;CG10726 barren fruit fly Drosophila melanogaster The D. melanogaster gene barren, abbreviated as barr, is reported here. It encodes a product involved in mitotic chromosome condensation which is localized to the mitotic chromosome. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 38B1--2. There are 14 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 10 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the peripheral nervous system and the neuron and are embryonic recessive lethal. barr is discussed in 43 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 studies of mutant phenotypes and 7 molecular studies. Among findings on barr mutants, mutations in barr cause a failure of chromosomes to segregate correctly at anaphase, resulting in massive anaphase bridging. FB FBgn0014127
3865 baz ;Bazooka;CG5055;dPar-3;l(1)G0484;Par-3;Par3 bazooka fruit fly Drosophila melanogaster The D. melanogaster gene bazooka, abbreviated as baz, is reported here. It has also been known in FlyBase as l(1)G0484 and par-3. It encodes a product with protein kinase C binding involved in follicle cell adhesion (sensu Insecta) which is localized to the cytoplasm and the cytoplasm | apical; it is expressed in the embryo (epithelial cell and neuroblast). It has been sequenced and its amino acid sequence contains a PDZ domain (also known as DHR or GLGF). It has been mapped by recombination to 1-56.7 and cytologically to 15F1. It interacts genetically with sdt and dlg1. There are 34 recorded alleles: 14 in vitro constructs (none available from the public stock centers), 19 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic epidermis and are embryonic recessive lethal. baz is discussed in 150 references (excluding sequence accessions), dated between 1984 and 2003. These include at least 5 studies of mutant phenotypes, 5 studies of wild-type function and 6 molecular studies. Among findings on baz mutants, baz mutants display a large dorsal hole and ventral hole. Among findings on baz function, baz is required for the establishment of apical-basal polarity in eye photoreceptors during early pupal stages. FB FBgn0000163
3866 bb anon-EST:Liang-1.69;anon-EST:Posey92;clone 1.69;ITS1;l(1)20Fa;NO;rDNA;rDNA repeat;rDNA unit;ribosomal RNA;rRNA;small nuclear RNA a;snRNA-a;Xbb bobbed fruit fly Drosophila melanogaster The D. melanogaster multicopy gene bobbed, abbreviated as bb, is reported here. It has also been known in FlyBase as anon-ESTPosey92, anon-Xh2, anon-Xh3 and snRNA-a. It encodes a product which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced. It has been mapped by recombination to 1-66.0 and cytologically to h26--h32. It interacts genetically with gt. There are 110 recorded alleles: 11 in vitro constructs (none available from the public stock centers), 98 classical mutants (5 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the macrochaeta and the abdominal tergite and are recessive visible and viable. bb is discussed in 264 references (excluding sequence accessions), dated between 1923 and 2004. These include at least 36 studies of mutant phenotypes, 7 studies of wild-type function, 4 studies of natural polymorphisms and 5 molecular studies. FB FBgn0000164
3867 Bbbf1 ;BBF-1 Box B-binding factor 1 fruit fly Drosophila melanogaster The D. melanogaster gene Box B-binding factor 1, abbreviated as Bbbf1, is reported here. It encodes a product with RNA polymerase II transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 25C6--10. There is one recorded allele, which is wild-type. Bbbf1 is discussed in 4 references (excluding sequence accessions), dated between 1992 and 2000. These include at least one molecular study. FB FBgn0011271
3868 bbx anon-19Fb;CG1414;CG32527;tu2 bobby sox fruit fly Drosophila melanogaster The D. melanogaster gene bobby sox, abbreviated as bbx, is reported here. It has also been known in FlyBase as anon-19Fb. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a HMG1/2 (high mobility group) box. There are 4 recorded alleles: 1 in vitro construct (not available from the public stock centers), 2 classical mutants (1 available from the public stock centers) and 1 wild-type. bbx is discussed in 7 references (excluding sequence accessions), dated between 1993 and 2002. These include at least one study of wild-type function and 4 molecular studies. FB FBgn0024251
3870 bcd 107/12;5A;Bcd;BcDNA.GM05329;BcDNA:GM05329;BG:DS00276.7;bic;bicoid;Btf;CG1034;CG14578;CG3644;CG40105;E(2)Bic;E(Bic);Enhancer of Bicaudal;l(2)49Da;l(2)k10712;l(2)vr22;multimorph;mum;mum: multimorph;PRD gene 4;prd4;vr22 bicoid fruit fly Drosophila melanogaster The D. melanogaster gene bicoid, abbreviated as bcd, is reported here. It encodes a product with morphogen activity involved in determination of anterior/posterior axis, embryo which is localized to the nucleus; it is expressed in the ovary (nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 3-48 and cytologically to 84A5. It interacts genetically with hb, exu, RpII140, nos, Sry-δ and 5 other listed genes. There are 368 recorded alleles: 344 in vitro constructs (none available from the public stock centers), 23 classical mutants (11 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the acron, the pole cell, the maternal effect embryonic head and 23 other listed tissues and are embryonic maternal effect lethal and female sterile. bcd is discussed in 749 references (excluding sequence accessions), dated between 1983 and 2003. These include at least 82 studies of mutant phenotypes, 4 studies of wild-type function, 2 studies of natural polymorphisms and 35 molecular studies. Among findings on bcd mutants, several mutations have been isolated that fail to compensate for the fate change caused by the alteration in the bcd gradient. FB FBgn0000166
3874 BEAF-32 BEAF;BEAF-32A;BEAF-32B;BEAF32;BEAF32A;BEAF32B;boundary element associated factor;Boundary element-associated factor of 32kD;bs04c01.y1;CG10159 Boundary element-associated factor of 32kD fruit fly Drosophila melanogaster The D. melanogaster gene Boundary element-associated factor of 32kD, abbreviated as BEAF-32, is reported here. It has also been known in FlyBase as Beaf32. It encodes a product with DNA binding which is localized to the nucleus. It has been sequenced and its amino acid sequence contains a BED finger. It has been mapped cytologically to 51C2. It interacts genetically with Dref, Dll, kto and su(Hw). There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (available from the public stock centers) and 1 wild-type. BEAF-32 is discussed in 32 references (excluding sequence accessions), dated between 1995 and 2003. These include at least 4 studies of mutant phenotypes and 5 molecular studies. FB FBgn0015602
3889 bel anon-85Ab;BEL;BEL: BEL element;cap;CAP/Vinexin;capon;CG18408;CG18409;CG3451;CG9748;CG9802;DCAP;DmRH6;DmSMC3;DmSMC3/Cap;l(3)85Ac;l(3)L3;L3;ms(3)neo30;ms(3)Pneo85A;rexin;Smc3 belle fruit fly Drosophila melanogaster The D. melanogaster gene belle, abbreviated as bel, is reported here. It has also been known in FlyBase as CG9748, anon-85Ab and cap. It encodes a product with ATP dependent RNA helicase activity involved in spermatid development. It has been sequenced and its amino acid sequence contains a ATP-dependent helicase, DEAD-box, a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 85A5. There are 15 recorded alleles: 14 classical mutants (3 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the meiotic cycle, the spermatid and the chorion and are male sterile and female sterile. bel is discussed in 27 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 2 studies of mutant phenotypes and 3 molecular studies. FB FBgn0000171
3892 BEST:GH05123 ATP synthase;Hydrogen-transporting ATP synthase fruit fly Drosophila melanogaster The D. melanogaster gene BEST:GH05123 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) which is a component of the proton-transporting ATP synthase complex (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. BEST:GH05123 is discussed in one reference (excluding sequence accessions), dating from 2000. FB FBgn0043836
3894 BEST:GH17330 ;EP(X)1408;GH17330 fruit fly Drosophila melanogaster The D. melanogaster gene BEST:GH17330 is reported here. It encodes a product which is putatively a component of the mitochondrial membrane. It has been sequenced. It has been mapped cytologically to 3E6--7. It interacts genetically with H, N and pnr. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. BEST:GH17330 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2002. These include at least 2 studies of mutant phenotypes and one molecular study. FB FBgn0043460
3906 Bgb ;Big-brother;CG7959;en(lz)D/9;rp&bgr;2;rpbeta2;runt domain partner &bgr;2;runt domain partner beta2 Big brother fruit fly Drosophila melanogaster The D. melanogaster gene Big brother, abbreviated as Bgb, is reported here. It encodes a product with transcription coactivator activity involved in regulation of transcription from Pol II promoter which is a component of the core-binding factor complex; it is expressed in the embryo (embryonic central nervous system). It has been sequenced and its amino acid sequence contains a core binding factor β subunit. It has been mapped cytologically to 62A12. It interacts genetically with lz and Bro. There are 9 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the abdominal vch1 neuron and the (with Df(3L)Bgb-K4) abdominal vch1 neuron and are embryonic recessive lethal. Bgb is discussed in 26 references (excluding sequence accessions), dated between 1995 and 2003. These include at least 4 studies of mutant phenotypes and 5 molecular studies. FB FBgn0013753
3909 bi BI;CG3578;dm-omb;l(1)bi;l(1)omb;omb;omb: optomotor blind;optomoter blind;optomotor blind;optomotor-blind;optomotor-blind gene;optomotorblind;Qd;Qd: Quadroon;Quadroon;T3 bifid fruit fly Drosophila melanogaster The D. melanogaster gene bifid, abbreviated as bi, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in pigmentation which is a component of the nucleus; it is expressed in the adult (lamina neuropil, medulla cortex and protocerebrum), embryo (antennal segment, antenno-maxillary complex, embryonic peripheral nervous system, lateral accessory lobes and 3 other listed tissues), larva (dorsal mesothoracic disc, eye-antennal disc, lamina neuropil, larval brain and 2 other listed tissues) and prepupa and pupa (inner proliferation zone and suture). It has been sequenced and its amino acid sequence contains a T-box domain and a brachyury protein family. It has been mapped cytologically to 4C3--4. It interacts genetically with ap, dpp, Bx, cp, sd and 8 other listed genes. There are 37 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 34 classical mutants (4 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the distal wing and are pupal lethal. bi is discussed in 182 references (excluding sequence accessions), dated between 1916 and 2003. These include at least 12 studies of mutant phenotypes, 6 studies of wild-type function and 7 molecular studies. Among findings on bi mutants, mutations in the optic lobe regulatory region of the bi locus are viable and cause recognisable aberrations in the adult brain with concomitant specific defects in optomotor behavior. Among findings on bi function, bi is sufficient to specify dorsal leg cell fate. FB FBgn0000179
3910 bib ;BIB_DROME;CG4722;EP(2)2278;l(2)neo66;l(2)neo91;m-bib big brain fruit fly Drosophila melanogaster The D. melanogaster gene big brain, abbreviated as bib, is reported here. It encodes a product with connexon channel activity involved in mesoderm development which is localized to the plasma membrane; it is expressed in the embryo (Malpighian tubule, amnioproctodeal invagination, amnioserosa, ectoderm and 8 other listed tissues), larva (adepithelial cell of dorsal mesothoracic disc, flight muscle, sense organ and wing vein) and prepupa and pupa (eo neuron, epidermis, thecogen cell, tormogen cell and trichogen cell). It has been sequenced and its amino acid sequence contains a MIP family. It has been mapped by recombination to 2-34.7 and cytologically to 30F5. It interacts genetically with N, Dl and pnr. There are 21 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 18 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic epidermis, the embryonic central nervous system, the embryonic larval salivary gland and 18 other listed tissues and are embryonic neurogenic lethal. bib is discussed in 121 references (excluding sequence accessions), dated between 1981 and 2003. These include at least 13 studies of mutant phenotypes, 4 studies of wild-type function, one study of natural polymorphisms and 6 molecular studies. Among findings on bib mutants, neural hyperplasia, caused by mutations in bib, can be prevented by the presence of another neurogenic mutation. Among findings on bib function, bib function is required autonomously in epidermal precursors to prevent neural development. FB FBgn0000180
3912 BicC BG:DS00913.2;Bic-C;Bicaudal-C;br34;CG4824;l(2)br34 Bicaudal C fruit fly Drosophila melanogaster The D. melanogaster gene Bicaudal C, abbreviated as BicC, is reported here. It encodes a product with RNA binding involved in oogenesis (sensu Insecta) which is a component of the integral to plasma membrane; it is expressed in the ovary (germarium region 2a,2b,3, nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a KH domain. It has been mapped by recombination to 2-51 and cytologically to 35E2. It interacts genetically with bic. There are 18 recorded alleles: 17 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the follicle cell and are maternal effect lethal. BicC is discussed in 71 references (excluding sequence accessions), dated between 1982 and 2003. These include at least 3 studies of mutant phenotypes and 10 molecular studies. FB FBgn0000182
3915 bigmax BIGMAX;CG3350;DmMlx fruit fly Drosophila melanogaster The D. melanogaster gene bigmax is reported here. It has also been known in FlyBase as CG3350. It encodes a product with transcription factor activity involved in regulation of transcription which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain. It has been mapped cytologically to 97F1. There is one recorded allele, which is wild-type. bigmax is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039509
3916 bin ;Biniou;CG18647;Distal W5.4 Group XIV;Dmbin;FoxF;l(3)65CEe;XIV biniou fruit fly Drosophila melanogaster The D. melanogaster gene biniou, abbreviated as bin, is reported here. It has also been known in FlyBase as Biniou, CG18647 and l(3)65CEe. It encodes a product with transcription factor activity involved in regulation of transcription which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a fork head domain. It has been mapped cytologically to 65D6. There are 6 recorded alleles: 1 in vitro construct (not available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the circular visceral mesoderm and the midgut constriction and are lethal. bin is discussed in 13 references (excluding sequence accessions), dated between 1995 and 2003. These include at least one study of wild-type function and 2 molecular studies. Among findings on bin function, bin is essential for maintaining the distinction between the splanchnic (visceral) and somatic mesoderm and for differentiation of the splanchnic mesoderm into midgut musculature. FB FBgn0045759
3917 Bin1 BcDNA:RE02417;Bicoid interacting protein 1;bin1;bin1/dSAP18;CG6046;dSAP18;SAP18;Sin3A-associated polypeptide p18 Bicoid interacting protein 1 fruit fly Drosophila melanogaster The D. melanogaster gene Bicoid interacting protein 1, abbreviated as Bin1, is reported here. It has also been known in FlyBase as BcDNA:RE02417, CG6046 and SAP18. It encodes a product with transcription corepressor activity involved in negative regulation of transcription from Pol II promoter. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 89B7. It interacts genetically with Trl. There are 4 recorded alleles: 1 in vitro construct (not available from the public stock centers), 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing, the embryonic stage, the larval stage and 3 other listed tissues and are poor viable, dominant visible, female fertile, male sterile and melanotic 'tumor'. Bin1 is discussed in 20 references (excluding sequence accessions), dated between 1998 and 2003. These include at least one study of mutant phenotypes and 4 molecular studies. FB FBgn0024491
3918 bip2 bip-II;CG2009;dBIP2;dTAFII155;dTAF[[II]]155;i163;i31;TAF3;TAFII155;TAFII155;TAF[[II]]155;TFIID fruit fly Drosophila melanogaster The D. melanogaster gene bip2 is reported here. It encodes a product with general RNA polymerase II transcription factor activity which is a component of the transcription factor TFIID complex. It has been sequenced and its amino acid sequence contains a PHD-finger. It has been mapped cytologically to 102C1. There is one recorded allele, which is wild-type. bip2 is discussed in 20 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0026262
3920 Bj1 BJ1;CG10480;CG10480 (Bj1);CG18640;CG18640 (Bj1);CG18640 (Bj1), RCC protein;in excess;inxs;RanGEF;RanGEF (Bj1);RCC protein;RCC1;RCC1 (Bj1);sdt;side-out Bj1 protein fruit fly Drosophila melanogaster The D. melanogaster gene Bj1 protein, abbreviated as Bj1, is reported here. It encodes a product with Ran guanyl-nucleotide exchange factor activity involved in chromosome condensation which is localized to the nucleus; it is expressed in the embryo (embryonic central nervous system and neuroblast), larva (embryonic/larval salivary gland) and ovary (nurse cell and oocyte). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 65A1. It interacts genetically with Sd. There are 4 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Bj1 is discussed in 31 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function, one study of natural polymorphisms and 3 molecular studies. FB FBgn0002638
3921 Bka BcDNA:RE14949;Bekka;CG4539;l(2)02695;mip;mip: more inner photoreceptors;missing imaginal precursors Bekka fruit fly Drosophila melanogaster The D. melanogaster gene Bekka, abbreviated as Bka, is reported here. It has also been known in FlyBase as BcDNA:RE14949, CG4539 and l(2)02695. It encodes a product with transcriptional activator activity involved in chromatin-mediated maintenance of transcription which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 30E1. It interacts genetically with Sxl and Ubx. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. Bka is discussed in 10 references (excluding sequence accessions), dated between 1994 and 2001. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 2 molecular studies. FB FBgn0010520
3922 bl ;CG13425;CG30153;Heterogeneous nuclear ribonucleoprotein at 57A;Hrb57A;l(2)05056;l(2)k08305;Q18 bancal fruit fly Drosophila melanogaster The D. melanogaster gene bancal, abbreviated as bl, is reported here. It has also been known in FlyBase as CG13425, CG30153, Hrb57A, bancal and l(2)05056. It encodes a product with RNA binding putatively involved in induction of apoptosis which is localized to the cytoplasm and the nucleus; it is expressed in the larva (imaginal disc). It has been sequenced and its amino acid sequence contains a KH domain. It has been mapped cytologically to 57A6--7. It interacts genetically with N. There are 19 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 15 classical mutants (3 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the leg, the metathoracic femur, the metathoracic tarsal segment 1 and the (with blv5) leg and are recessive lethal, pharate adult recessive visible and (with blv5) visible. bl is discussed in 30 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of mutant phenotypes, 2 studies of wild-type function and 8 molecular studies. Among findings on bl function, the levels of bl protein affect cell proliferation and apoptosis in imaginal disc cells. FB FBgn0015907
3931 blw A2(2nd)27;ATP synthetase &agr; chain;ATP synthetase alpha chain;ATPsyn-&agr;;ATPsyn-alpha;CG3612;colibri;l(2)01410;l(2)03972;l(2)59ABa;l(2)k00212;mitochondrial ATP synthase alpha subunit;ms(2)01504;ms(2)Pry58F bellwether fruit fly Drosophila melanogaster The D. melanogaster gene bellwether, abbreviated as blw, is reported here. It has also been known in FlyBase as ATPsyn-α, l(2)01410, l(2)03972 and l(2)k00212. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukarya); it is expressed in the larva (dorsal mesothoracic disc). It has been sequenced and its amino acid sequence contains a ATP synthase α and β subunit, N-terminal and a ATP synthase α subunit, C-terminal. It has been mapped cytologically to 59B1--2. It interacts genetically with Dp and E2f. There are 24 recorded alleles: 23 classical mutants (3 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the somatic clone cell autonomous dorsal mesothoracic disc and are recessive lethal, recessive mitotic and somatic clone cell autonomous reduced cell size. blw is discussed in 23 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 2 studies of mutant phenotypes and 5 molecular studies. FB FBgn0011211
3933 Bmcp ;CG7314;DmBMCP;dmUCP5 fruit fly Drosophila melanogaster The D. melanogaster gene Bmcp is reported here. It has also been known in FlyBase as CG7314. It encodes a product with carrier activity putatively involved in cation transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial brown fat uncoupling domain, a mitochondrial carrier domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 68D3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Bmcp is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036199
3936 bnk ;CG1480 bottleneck fruit fly Drosophila melanogaster The D. melanogaster gene bottleneck, abbreviated as bnk, is reported here. It encodes a product with putative actin binding involved in cellularization which is localized to the actin filament. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 100B5. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. bnk is discussed in 32 references (excluding sequence accessions), dated between 1991 and 2003. These include at least one study of wild-type function and one molecular study. Among findings on bnk function, the expression pattern and mutant phenotype of bnk suggests a direct role in regulating the dynamic restructuring of the actin-based cytoskeleton of cellularizing embryos. FB FBgn0004389
3942 boca ;CG1364;CG30498;l(2)43Ea;l(2)43Ea: lethal(2)43Ea;lethal(2)43Ea boca fruit fly Drosophila melanogaster The D. melanogaster gene boca is reported here. It has also been known in FlyBase as CG1364, CG30498 and l(2)43Ea. It encodes a product involved in ER to Golgi transport which is a component of the cytoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 43D7. There are 5 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the somatic clone cell autonomous wing margin bristle, the somatic clone dorsocentral bristle, the ectopic somatic clone eye and 4 other listed tissues and are pupal recessive lethal. boca is discussed in 10 references (excluding sequence accessions), dated between 1993 and 2003. These include at least one study of mutant phenotypes, 2 studies of wild-type function and one molecular study. Among findings on boca function, boca is essential for proboscis development, and viability. FB FBgn0004132
3943 bol BcDNA:AT13332;Boule;CG4727;CG4760;ms(3)07272 boule fruit fly Drosophila melanogaster The D. melanogaster gene boule, abbreviated as bol, is reported here. It has also been known in FlyBase as BcDNA:AT13332 and CG4727. It encodes a product with RNA binding involved in spermatogenesis which is a component of the nucleus; it is expressed in the adult (testis). It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 66F5--6. It interacts genetically with twe. There are 9 recorded alleles: 1 in vitro construct (not available from the public stock centers), 7 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the testis, the Nebenkern, the primary spermatocyte cyst and 2 other listed tissues and are recessive male sterile and male meiotic. bol is discussed in 43 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 2 studies of mutant phenotypes, 2 studies of wild-type function and 2 molecular studies. Among findings on bol function, bol has an essential meiotic function in spermatogenesis. FB FBgn0011206
3944 bon 0241/08;0249/12;0434/20;0487/06;anon-WO0118547.418;Bonus;CG15687;CG5206;l(3)S043420 bonus fruit fly Drosophila melanogaster The D. melanogaster gene bonus, abbreviated as bon, is reported here. It has also been known in FlyBase as CG15687 and CG5206. It encodes a product with putative transcription coactivator activity involved in peripheral nervous system development which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a B-box zinc finger superfamily and a PHD-finger. It has been mapped cytologically to 92F2--3. It interacts genetically with ftz-f1. There are 17 recorded alleles: 12 in vitro constructs (none available from the public stock centers), 4 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the (with Df(3R)H-B79) embryonic/larval tracheal system, the pupal (with bonS048706) eye, the pupal (with bonS048706) wing and 3 other listed tissues and are recessive lethal and recessive somatic clone cell lethal. bon is discussed in 21 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one study of mutant phenotypes and one molecular study. FB FBgn0023097
3945 bonsai ;CG4207;DmMRPS15;MRP-S15;mRpS15 fruit fly Drosophila melanogaster The D. melanogaster gene bonsai is reported here. It has also been known in FlyBase as CG4207. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a ribosomal protein S15. It has been mapped cytologically to 58F3. It interacts genetically with Dp and E2f. There are 7 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult and are larval partially recessive lethal, recessive visible, size defective and developmental rate defective. bonsai is discussed in 14 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 studies of mutant phenotypes and 3 molecular studies. Among findings on bonsai mutants, bonsai mutants appear to have defective mitochondrial activity in the gut. FB FBgn0026261
3948 boss Bos;Boss;CG8285;F;F transcript;X55887 bride of sevenless fruit fly Drosophila melanogaster The D. melanogaster gene bride of sevenless, abbreviated as boss, is reported here. It encodes a product with sevenless binding involved in eye morphogenesis (sensu Drosophila) which is localized to the microvilli; it is expressed in the adult (adult head), larva (eye-antennal disc, imaginal disc, photoreceptor cell R8 and ventral thoracic disc) and prepupa and pupa (eye-antennal disc, ocellus, photoreceptor cell R1 to 8 and retina). It has been sequenced and its amino acid sequence contains a G-protein coupled receptors family 3 (Metabotropic glutamate receptor-like) and a bride of sevenless domain. It has been mapped by recombination to 3-90.5 and cytologically to 96F8. It interacts genetically with sev, Sos, Gap1, Src42A and H. There are 53 recorded alleles: 18 in vitro constructs (1 available from the public stock centers), 34 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the photoreceptor cell R7 and are viable. boss is discussed in 226 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 20 studies of mutant phenotypes, one study of wild-type function, 5 studies of natural polymorphisms and 8 molecular studies. FB FBgn0000206
3949 botv BcDNA:LD21192;Botv;brother of tout-velu;CG15110;DEXT3;Dextl3;Drosophila Ext-like 3 brother of tout-velu fruit fly Drosophila melanogaster The D. melanogaster gene brother of tout-velu, abbreviated as botv, is reported here. It has also been known in FlyBase as BcDNA:LD21192. It encodes a product with acetylglucosaminyltransferase activity (EC:2.4.1.-) involved in heparan sulfate proteoglycan biosynthesis, polysaccharide chain biosynthesis which is putatively a component of the integral to membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 56B5. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. botv is discussed in 12 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one study of wild-type function and 2 molecular studies. FB FBgn0027535
3950 bowl 17-29-5;bowel;Bowl;CG10021;l(2)c;l(2)k08617;odd skipped-related 2;org2;org2: odd skipped-related 2;Su(tor)2-1 brother of odd with entrails limited fruit fly Drosophila melanogaster The D. melanogaster gene brother of odd with entrails limited, abbreviated as bowl, is reported here. It has also been known in FlyBase as Su(tor)2-1 and l(2)k08617. It encodes a product with RNA polymerase II transcription factor activity involved in leg joint morphogenesis (sensu Holometabola) which is a component of the nucleus; it is expressed in the embryo (amnioproctodeal invagination, anterior embryonic/larval midgut, cephalic furrow, embryonic/larval foregut and 4 other listed tissues). It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped by recombination to 2-16 and cytologically to 24C3--4. It interacts genetically with tor, Src42A and phl. There are 20 recorded alleles: 1 in vitro construct (not available from the public stock centers), 18 classical mutants (5 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic mandibular segment, the embryonic maxillary segment, the embryonic larval hindgut and 9 other listed tissues and are embryonic recessive lethal and somatic clone visible. bowl is discussed in 35 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 5 studies of mutant phenotypes, 4 studies of wild-type function and 6 molecular studies. Among findings on bowl function, bowl is required for patterning of the hindgut. FB FBgn0004893
3951 br ;2B5;2Bc;A18;BR-c;BR-C Z1;br-Z1;br-Z3;BRC;BrC-Z1;broad complex;Broad-Complex;BR_C;C93;CG11491;CG11511;CG11514;CG7752;DCE-12;de12;ecdysone-sensitivity;ecs;ecs: ecdysone-sensitivity;EG:123F11.1;EG:17A9.1;EG:25D2.1;l(1)1Db;l(1)2Ba;l(1)2Bab;l(1)2Bad;l(1)2Bb;l(1)2Bc;l(1)2Bd;l(1)d norm-12;l(1)d.norm.1;l(1)dn1;l(1)ESHS5;l(1)G0018;l(1)G0042;l(1)G0284;l(1)G0284a;l(1)G0318;l(1)G0401;l(1)n34;l(1)npr-1;l(1)npr1;l(1)pp-1;l(1)pp-2;l(1)PP1;l(1)pp2;l(1)ts132;l(1)ts144;l(1)ts358;l(1)ts376;lethal(1)2Bab;lethal(1)2Bc;lethal(1)2Bd;lethal(1)discs normal;lethal(1)non-pupariating-1;non-pupariating;non-pupariating-1;npr;npr-1;npr1;npr1: non-pupariating-1;nprl;nrp;o.c.c.;overlapping-complementation-complex;p160;PP1;PP2;rbp;rdp;rds;reduced bristles on palps;reduced palps;unequal wings;uq;Z1;Z2;Z3;Z4 broad fruit fly Drosophila melanogaster The D. melanogaster gene broad, abbreviated as br, is reported here. It has also been known in FlyBase as BRC, CG11491, CG11511, CG11514, l(1)2Bab, l(1)2Bc, l(1)2Bd, l(1)ESHS5, l(1)G0018, l(1)G0042, l(1)G0284, l(1)G0284a, l(1)G0318, l(1)G0401, npr and rbp. It encodes a product with DNA binding involved in salivary gland histolysis which is a component of the nucleus; it is expressed in the ovary (ovary). It has been sequenced and its amino acid sequence contains a BTB/POZ domain and a zinc finger, C2H2 type. It has been mapped by recombination to 1-0.28 and cytologically to 2B3--5. It interacts genetically with Sb, zip, Eip74EF, B and ftz-f1. There are 110 recorded alleles: 11 in vitro constructs (none available from the public stock centers), 98 classical mutants (4 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the (with br2Bab-1) metathoracic tarsal segment, the optic lobe, the adult brain and 9 other listed tissues and are recessive lethal, (with brBC3) visible and (with br25.4) visible. br is discussed in 325 references (excluding sequence accessions), dated between 1916 and 2003. These include at least 29 studies of mutant phenotypes, 8 studies of wild-type function and 7 molecular studies. Among findings on br mutants, mutations at br reduce the transcription rate or stability of the small heat shock protein mRNAs. Among findings on br function, br is required for salivary gland, autophagic, cell death. FB FBgn0000210
3955 Brf BRF;BRF1;CG31256;CG4155;CG5419;IIIB;TFIIIB fruit fly Drosophila melanogaster The D. melanogaster gene Brf is reported here. It has also been known in FlyBase as CG4155 and CG5419. It encodes a product with RNA polymerase III transcription factor activity involved in regulation of transcription from Pol III promoter which is a component of the transcription factor TFIIIB complex. It has been sequenced and its amino acid sequence contains a transcription factor TFIIB repeat. It has been mapped cytologically to 90A3--5. There is one recorded allele, which is wild-type. Brf is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038499
3956 brk Brinker;Brk;CG9653;small salivary glands-1;ssg-1 brinker fruit fly Drosophila melanogaster The D. melanogaster gene brinker, abbreviated as brk, is reported here. It encodes a product with specific transcriptional repressor activity involved in transforming growth factor beta receptor signaling pathway which is localized to the nucleus; it is expressed in the embryo (ectoderm, embryonic/larval midgut, endoderm, mesoderm and 4 other listed tissues) and larva (dorsal mesothoracic disc and ventral thoracic disc). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-19.6 and cytologically to 7B1. It interacts genetically with shn, dpp, tkv, tsh and ey. There are 36 recorded alleles: 11 in vitro constructs (none available from the public stock centers), 24 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic dorsal epidermis, the wing, the denticle belt and 5 other listed tissues and are recessive lethal and neuroanatomy defective. brk is discussed in 105 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 7 studies of mutant phenotypes, 5 studies of wild-type function and 7 molecular studies. Among findings on brk mutants, brk mutations are embryonic lethal. Among findings on brk function, brk not only plays a role in dorsal-ventral but also in anterior-posterior axis patterning. FB FBgn0024250
3957 brm BRM;CG18438;CG5942;Complementation group 3.5;dBRM;E(E2F)3A;l(3)72Aa brahma fruit fly Drosophila melanogaster The D. melanogaster gene brahma, abbreviated as brm, is reported here. It has also been known in FlyBase as CG18438. It encodes a product with general RNA polymerase II transcription factor activity involved in oogenesis (sensu Insecta) which is a component of the nucleus; it is expressed in the unfertilized egg). It has been sequenced and its amino acid sequence contains a SNF2 related domain, a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped by recombination to 3-43.0 and cytologically to 72C1. It interacts genetically with Antp, trx, Psc, Snr1, osa and 30 other listed genes. There are 38 recorded alleles: 7 in vitro constructs (none available from the public stock centers), 30 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the abdominal segment 6, the larval hemocyte and the wing and are recessive lethal and recessive somatic clone visible. brm is discussed in 168 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 29 studies of mutant phenotypes, 9 studies of wild-type function and 13 molecular studies. Among findings on brm function, the chromatin remodelling activity of the brm complex may play a general role in facilitating transcription by RNA polymerase II. FB FBgn0000212
3959 Bro Beta for Runt and OTHERs;CG7960;rp&bgr;1;rpbeta1;runt domain partner &bgr;1;runt domain partner beta1 Brother fruit fly Drosophila melanogaster The D. melanogaster gene Brother, abbreviated as Bro, is reported here. It encodes a product with transcription coactivator activity involved in eye morphogenesis (sensu Drosophila) which is a component of the core-binding factor complex. It has been sequenced and its amino acid sequence contains a core binding factor β subunit. It has been mapped cytologically to 62A12. It interacts genetically with run, lz and Bgb. There are 4 recorded alleles: 3 in vitro constructs (none available from the public stock centers) and 1 wild-type. Bro is discussed in 22 references (excluding sequence accessions), dated between 1995 and 2003. These include at least 2 studies of wild-type function and 4 molecular studies. FB FBgn0013755
3963 bs ba;ba: balloon;balloon;BS;CG3411;CG4444;D-SRF;DmSRF;DSRF;DSrf/bs;Group IIc;l(2)03267;pruned;pruned/DSRF;px;Serf;Serum Response Factor;Srf blistered fruit fly Drosophila melanogaster The D. melanogaster gene blistered, abbreviated as bs, is reported here. It has also been known in FlyBase as Serf and l(2)03267. It encodes a product with RNA polymerase II transcription factor activity involved in terminal branching of trachea, cytoplasmic projection extension (sensu Insecta) which is localized to the nucleus; it is expressed in the embryo (abdominal segment 1 to 8, embryonic central nervous system, embryonic/larval hindgut, embryonic/larval midgut and 4 other listed tissues). It has been sequenced and its amino acid sequence contains a MADS-box domain. It has been mapped by recombination to 2-107.3 and cytologically to 60C6--7. It interacts genetically with mys, rho, Dl, if, vn and 13 other listed genes. There are 47 recorded alleles: 46 classical mutants (5 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the somatic clone wing, the somatic clone cell non-autonomous wing vein and the trachea and are larval lethal, somatic clone cell autonomous reduced cell size and dominant visible. bs is discussed in 143 references (excluding sequence accessions), dated between 1917 and 2003. These include at least 16 studies of mutant phenotypes, 7 studies of wild-type function and 6 molecular studies. Among findings on bs function, bs is involved in cell fate allocation and differentiation but does not participate in cell proliferation. (However, there is much more information on function so that may not be representative.) FB FBgn0004101
3965 bsh &lgr;E86;Bsh;Bsh: Bashed;CG10604;E86;Hox11-310;lambdaE86 brain-specific homeobox fruit fly Drosophila melanogaster The D. melanogaster gene brain-specific homeobox, abbreviated as bsh, is reported here. It has also been known in FlyBase as Hox11-310. It encodes a product with transcription factor activity involved in brain development which is localized to the nucleus; it is expressed in the adult (lamina), embryo (supraesophageal ganglion) and larva (optic lobe). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors and a homeobox domain. It has been mapped cytologically to 38A3. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. bsh is discussed in 25 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 4 molecular studies. FB FBgn0000529
3966 bsk basket;CG5680;D-JNK;D-junk;DBSK/JNK;DJNK;DJNK/bsk;JNK;JNK/SAPK;Jun kinase;Jun N-terminal kinase;Jun-kinase;Junk;SAPKa basket fruit fly Drosophila melanogaster The D. melanogaster gene basket, abbreviated as bsk, is reported here. It has also been known in FlyBase as CG5680 and Junk. It encodes a product with JUN kinase activity (EC:2.7.1.-) involved in JNK cascade which is a component of the nucleus; it is expressed in the fat body and hemocyte), embryo (anterior transverse furrow, cephalic furrow, embryonic brain, embryonic central nervous system and 4 other listed tissues) and larva (dorsal mesothoracic disc, eye imaginal disc and imaginal disc). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped by recombination to 2-33 and cytologically to 31B3. It interacts genetically with dsh, Jra, msn, cno, Tak1 and 15 other listed genes. There are 17 recorded alleles: 10 in vitro constructs (2 available from the public stock centers), 6 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic dorsal cuticle, the embryonic dorsal epidermis, the somatic clone photoreceptor cell and the somatic clone ommatidium and are embryonic lethal. bsk is discussed in 179 references (excluding sequence accessions), dated between 1984 and 2003. These include at least 24 studies of mutant phenotypes, 9 studies of wild-type function and 10 molecular studies. Among findings on bsk function, bsk functions in the establishment of planar polarity in the eye. FB FBgn0000229
3970 btb bumper-to-bumper fruit fly Drosophila melanogaster The D. melanogaster gene bumper-to-bumper, abbreviated as btb, is reported here. It encodes a product with DNA-directed RNA polymerase activity (EC:2.7.7.6) involved in transcription from Pol III promoter which is a component of the DNA-directed RNA polymerase III complex. It has been sequenced. It has been mapped cytologically to 47A--B. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic peripheral nervous system and the lateral chordotonal organ and are embryonic recessive lethal. btb is discussed in 6 references (excluding sequence accessions), dated between 1994 and 2000. FB FBgn0015368
3972 btd BTD;CG12653 buttonhead fruit fly Drosophila melanogaster The D. melanogaster gene buttonhead, abbreviated as btd, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in specification of segmental identity, head which is a component of the nucleus; it is expressed in the embryo (cephalic furrow and procephalic neurectoderm). It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped by recombination to 1-31 and cytologically to 8F10. It interacts genetically with Sp1. There are 22 recorded alleles: 12 in vitro constructs (none available from the public stock centers), 7 classical mutants (1 available from the public stock centers) and 3 wild-type. Amorphic mutations have been isolated which affect the embryonic mandibular segment, the embryonic intercalary segment, the embryonic antennal segment and 2 other listed tissues and are embryonic lethal. btd is discussed in 88 references (excluding sequence accessions), dated between 1984 and 2003. These include at least 4 studies of mutant phenotypes, 4 studies of wild-type function and 9 molecular studies. Among findings on btd mutants, btd mutants display incomplete head involution. Among findings on btd function, btd has a gap-gene-like role in mediating the development of head structures. FB FBgn0000233
3973 Bteb2 ;CG2932 fruit fly Drosophila melanogaster The D. melanogaster gene Bteb2 is reported here. It encodes a product with RNA polymerase II transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 4D1. There is one recorded allele, which is wild-type. Bteb2 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0025679
3974 Btk29A ;c-src/fps;C-src2;C-src4;CG18355;CG8049;CT2415;CT41718;Dm SRC2;DSrc28;Dsrc28C;dsrc29A;DTec29;fic;fickle;S13;SRC 29A;Src oncogene;Src oncogene 29A;src-4;src2;src28C;Src29A;Src29A: Src oncogene 29A;src4;Tec;Tec29;Tec29A Btk family kinase at 29A fruit fly Drosophila melanogaster The D. melanogaster gene Btk family kinase at 29A, abbreviated as Btk29A, is reported here. It has also been known in FlyBase as CG18355 and Src29A. It encodes a product with protein-tyrosine kinase activity (EC:2.7.1.112) involved in head involution which is a component of the plasma membrane; it is expressed in the adult (adult dorsal vessel, adult head, cardia and ejaculatory bulb), embryo (amnioserosa, anterior midgut primordium, ectoderm, embryonic central nervous system and 11 other listed tissues), larva (gonad, imaginal disc, larval central nervous system, lymph gland and 5 other listed tissues), ovary (nurse cell, oocyte, ovary and ring canal) and prepupa and pupa (genital disc, imaginal disc, male genital disc, histoblast and 2 other listed tissues). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a src homology 2 (SH2) domain, a tyrosine kinase catalytic domain and a tec/Btk domain. It has been mapped cytologically to 29A1. It interacts genetically with Src64B, Src42A, tor, Ras85D and pcs. There are 16 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 11 classical mutants (3 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the male genitalia and are male mating defective. Btk29A is discussed in 83 references (excluding sequence accessions), dated between 1983 and 2003. These include at least 6 studies of mutant phenotypes, 4 studies of wild-type function and 10 molecular studies. Among findings on Btk29A function, Btk29A is required for the development of the male genitalia and substrates required for adult survival. FB FBgn0003502
3975 btl 0844/01;Btl;BTL/FGFR2;CG32134;CG6714;CT20816;D-FGFR;dev;devenir;DFGF-R1;Dfr-2;DFR2;DmHD-311;dtk2;FGF receptor;fgf-r;Fgf-r: Fibroblast-growth-factor-receptor;FGFR;FGFR1;Fibroblast-growth-f;Fibroblast-growth-factor-receptor;HD-311;l(3)00208;Tk2 breathless fruit fly Drosophila melanogaster The D. melanogaster gene breathless, abbreviated as btl, is reported here. It has also been known in FlyBase as CG32134, HD-311 and dev. It encodes a product with fibroblast growth factor receptor activity involved in tracheal system development (sensu Insecta) which is localized to the plasma membrane; it is expressed in the embryo (VUM neuron, anterior midgut primordium, embryonic/larval salivary gland, embryonic/larval trachea and 6 other listed tissues). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a tyrosine kinase catalytic domain, an immunoglobulin and major histocompatibility complex domain, an immunoglobulin C-2 type and an immunoglobulin-like. It has been mapped by recombination to 3-40.9 and cytologically to 70D2. It interacts genetically with Pc, slbo, ph-p, bnl, vvl and 10 other listed genes. There are 31 recorded alleles: 11 in vitro constructs (none available from the public stock centers), 19 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic/larval tracheal system and are recessive lethal. btl is discussed in 199 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 16 studies of mutant phenotypes, 5 studies of wild-type function and 11 molecular studies. Among findings on btl function, spatially regulated btl activity guides tracheal cell migration and determines the pattern of secondary and terminal branches by selecting tracheal cell fates. FB FBgn0005592
3976 btn 1261/13;btn/MEOX;buttonless;CG5264 buttonless fruit fly Drosophila melanogaster The D. melanogaster gene buttonless, abbreviated as btn, is reported here. It encodes a product with specific RNA polymerase II transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus; it is expressed in the embryo (dorsal neurohemal organ). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors, a 'POU' domain and a homeobox domain. It has been mapped cytologically to 94B5. It interacts genetically with pnr. There are 5 recorded alleles: 4 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the dorsal neurohemal organ and the abdominal transverse nerve and are recessive embryonic lethal. btn is discussed in 17 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 studies of mutant phenotypes and 4 molecular studies. FB FBgn0014949
3977 btv beethoven;CG15148;DHC;Dhc36D;Dynein heavy chain 36D beethoven fruit fly Drosophila melanogaster The D. melanogaster gene beethoven, abbreviated as btv, is reported here. It encodes a product involved in male courtship behavior (sensu Insecta), song production. It has been mapped cytologically to 36E1--3. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult antennal nerve, the wing, the arista and the mechanosensory sensory organ and are viable, behavioral, recessive auditory system defective, olfaction defective, male courtship defective, male fertile, song defective and neuroanatomy defective. btv is discussed in 17 references, dated between 1997 and 2003. These include at least 2 studies of mutant phenotypes. FB FBgn0023096
3978 btz barentsz;CG12878;weak localizer;wkl barentsz fruit fly Drosophila melanogaster The D. melanogaster gene barentsz, abbreviated as btz, is reported here. It has also been known in FlyBase as CG12878 and wkl. It encodes a product involved in pole plasm protein localization which is a component of the nuclear membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98B1--2. There are 7 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 3 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the maternal effect conditional cs ovariole, the conditional cs pole cell, the conditional cs ovary and the abdomen and are maternal effect conditional cs female sterile and visible. btz is discussed in 16 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of mutant phenotypes and 3 molecular studies. FB FBgn0045862
3979 Bub1 31/13;BcDNA:LD23835;bub1;BubR1;CG7838;dBUB1;Dmbub1;l(2)k03113;l(2)k06109 fruit fly Drosophila melanogaster The D. melanogaster gene Bub1 is reported here. It has also been known in FlyBase as l(2)k03113. It encodes a product with protein kinase activity (EC:2.7.1.37) involved in protein amino acid phosphorylation which is localized to the kinetochore. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 42A1--2. It interacts genetically with Cdc27, polo, dup and asp. There are 4 recorded alleles: 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the imaginal disc, the mitotic cycle and the mitotic anaphase and are recessive lethal and recessive mitotic. Bub1 is discussed in 44 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 6 studies of mutant phenotypes, one study of wild-type function and 6 molecular studies. Among findings on Bub1 mutants, loss of function mutations in Bub1 cause severe mitotic abnormalities consistent with accelerated transit through metaphase. FB FBgn0025458
3980 Bub3 ;CG7581;dBUB3;Dmbub3 fruit fly Drosophila melanogaster The D. melanogaster gene Bub3 is reported here. It encodes a product with putative RNA binding involved in mitotic checkpoint which is localized to the kinetochore; it is expressed in the adult (spermatocyte) and larva (neuroblast). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 99B7. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Bub3 is discussed in 14 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 4 molecular studies. FB FBgn0025457
3984 bun 1550;CG5461;EP(2)0488;l(2)00255;l(2)02687;l(2)05479;l(2)06475;l(2)k02903;l(2)rI043;short sighted;short-sighted;shortsighted;shs;TSC-22;Tsc22 bunched fruit fly Drosophila melanogaster The D. melanogaster gene bunched, abbreviated as bun, is reported here. It has also been known in FlyBase as Tsc22, l(2)rI043 and shs. It encodes a product with RNA polymerase II transcription factor activity involved in dorsal appendage formation which is localized to the cytoplasm; it is expressed in the larva (eye-antennal disc). It has been sequenced and its amino acid sequence contains a TSC-22 / Dip / Bun family. It has been mapped cytologically to 33E5--9. It interacts genetically with dpp, S, aop, hh and pnr. There are 42 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 36 classical mutants (6 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic cuticle and the embryonic segment and are larval recessive lethal. bun is discussed in 51 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and 6 molecular studies. FB FBgn0010460
3986 bw ;CG17632;Plum;Pm;Pm: Plum;pteridine-modifier;ptm;ptm: pteridine-modifier;Rosy;Su(wco2);Su(wcoJ);Su(w[co2]): Suppressor of white-coral-2;Su(w[coJ]);Suppressor of white-coral J;Suppressor of white-coral-2 brown fruit fly Drosophila melanogaster The D. melanogaster gene brown, abbreviated as bw, is reported here. It encodes a product with eye pigment precursor transporter activity involved in eye pigment precursor transport which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a ABC transporter. It has been mapped by recombination to 2-104.5 and cytologically to 59E2--3. It interacts genetically with w, ade2, v, Mod(Prat:bw)1-1 to 5, Mod(Prat:bw)2-1 and 14 other listed genes. There are 149 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 144 classical mutants (15 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the wing and the pigment cell and are eye color defective, dominant visible, viable and fertile. bw is discussed in 241 references (excluding sequence accessions), dated between 1921 and 2003. These include at least 19 studies of mutant phenotypes, one study of natural polymorphisms and 2 molecular studies. Among findings on bw mutants, a fifth of mutations selected on the basis of suppression of bwD carry rearrangements that modify PEV by changing the chromosomal position of bwD, suggesting that PEV depends on nuclear position. Among findings on bw polymorphisms, recessive bw eye color mutants have been isolated from the wild. FB FBgn0000241
3989 Bx ;Bd;Bd: Beaded;beadex/dLMO;CG6500;DLMO;dttg;flightless-H;fliH;hdp;hdp-a;hdp: heldup;heldup a;heldwing;hld;hld: heldwing;LIM-only;Lmo;maggot;mgg;mgt;Pointedoid;Ptd;Ptd: Pointedoid;Rho;Rho: Rhombotin;rhombotin Beadex fruit fly Drosophila melanogaster The D. melanogaster gene Beadex, abbreviated as Bx, is reported here. It has also been known in FlyBase as Lmo, hdp-a and mgg. It encodes a product with putative transcription regulator activity involved in wing morphogenesis which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-59.4 and cytologically to 17C3--4. It interacts genetically with ap, Chi, fng, Ser, bi and 13 other listed genes. There are 81 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 76 classical mutants (6 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the dorsal compartment wing and the wing vein and are visible. Bx is discussed in 87 references (excluding sequence accessions), dated between 1925 and 2003. These include at least 12 studies of mutant phenotypes, 2 studies of wild-type function and 3 molecular studies. Among findings on Bx mutants, Bx1 interpreted as mutation in cis-acting control element causing overproduction of hdp-a gene product. Among findings on Bx function, germline clonal analysis demonstrates Bx is required for germline development. FB FBgn0000242
3990 Bx42 ;CG8264 Bx42 fruit fly Drosophila melanogaster The D. melanogaster gene Bx42 is reported here. It encodes a product putatively involved in transcription from Pol II promoter which is localized to the nucleus; it is expressed in the adult (follicle cell and nurse cell) and larva (larval salivary gland). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 8C9. It interacts genetically with Su(H). There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. Bx42 is discussed in 12 references (excluding sequence accessions), dated between 1990 and 2003. These include at least 3 molecular studies. FB FBgn0004856
3991 by 3R-B;BcDNA:RE65113;CG9379;CT26639;tensin blistery fruit fly Drosophila melanogaster The D. melanogaster gene blistery, abbreviated as by, is reported here. It has also been known in FlyBase as 3R-B, CG9379 and tensin. It encodes a product with actin binding involved in wing morphogenesis which is a component of the focal adhesion. It has been sequenced and its amino acid sequence contains a phosphotyrosine interaction (PID or PI) and a src homology 2 (SH2) domain. It has been mapped by recombination to 3-48.7 and cytologically to 85D22. It interacts genetically with if, bsk and hep. There are 15 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 10 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing, the thorax and the (with by2) wing and are recessive visible and (with by2) visible. by is discussed in 22 references (excluding sequence accessions), dated between 1934 and 2003. These include at least one study of mutant phenotypes and 2 molecular studies. FB FBgn0000244
3992 byn apro;apro: aproctous;aproctous;Brachyenteron;Byn;byn/apro;CG16724;CG7260;D-TRA;D-Trg;Dm-BYN;dm-Trg;Dmtra;DTrg;T related antigen;T-related gene;Tra;trg;Trg: T-related gene brachyenteron fruit fly Drosophila melanogaster The D. melanogaster gene brachyenteron, abbreviated as byn, is reported here. It has also been known in FlyBase as Tra and Trg. It encodes a product with RNA polymerase II transcription factor activity involved in hindgut morphogenesis which is localized to the nucleus; it is expressed in the embryo (anal pad, embryonic/larval hindgut and proctodeum). It has been sequenced and its amino acid sequence contains a T-box domain and a brachyury protein family. It has been mapped cytologically to 68E3. It interacts genetically with fkh and tor. There are 13 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 9 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the hindgut specific anlage, the Malpighian tubule, the embryonic anal pad and 12 other listed tissues and are (with byn2) short lived, partially (with byn2) lethal, recessive lethal, (with byn2) female sterile, (with byn1) lethal, (with byn3 to 4) lethal and (with byn6) lethal. byn is discussed in 48 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 studies of mutant phenotypes, 7 studies of wild-type function and 3 molecular studies. Among findings on byn function, phenotypic analysis demonstrates byn is required to regulate specific gene activity in the primordia of the anal pads and hindgut. FB FBgn0011723
3993 c(2)M BG:DS02740.10;CG4249;crossover suppressor on 2 of Manheim;DS02740.10;MEI-910 crossover suppressor on 2 of Manheim fruit fly Drosophila melanogaster The D. melanogaster gene crossover suppressor on 2 of Manheim, abbreviated as c(2)M, is reported here. It has also been known in FlyBase as BG:DS02740.10 and mei-910. It encodes a product involved in meiosis which is a component of the synaptonemal complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 35F7. There are 6 recorded alleles: 1 in vitro construct (not available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which are meiotic. c(2)M is discussed in 14 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 studies of mutant phenotypes, 2 studies of wild-type function and 4 molecular studies. Among findings on c(2)M function, c(2)M promoted the formation of crossovers. FB FBgn0028525
3994 c(3)G C(3)G;c3G;CG17604;CG3126;cx;DC3G crossover suppressor on 3 of Gowan fruit fly Drosophila melanogaster The D. melanogaster gene crossover suppressor on 3 of Gowan, abbreviated as c(3)G, is reported here. It has also been known in FlyBase as CG17604. It encodes a product with putative microtubule binding involved in meiotic recombination which is a component of the synaptonemal complex. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-57.4 and cytologically to 89A5. It interacts genetically with okr. There are 8 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the synaptonemal complex and are female meiotic. c(3)G is discussed in 63 references (excluding sequence accessions), dated between 1922 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 3 molecular studies. Among findings on c(3)G function, c(3)G is required for recombination and synaptonemal complex assembly. FB FBgn0000246
3996 C15 311;93Bal;CG7937;clawless;cll;Ect5;Hox11-311 C15 fruit fly Drosophila melanogaster The D. melanogaster gene C15 is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in mesoderm cell fate specification which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 93E3. There is one recorded allele, which is wild-type. C15 is discussed in 14 references (excluding sequence accessions), dated between 1993 and 2003. These include at least one study of wild-type function and 4 molecular studies. Among findings on C15 function, in situ and antibody staining show that C15 is expressed in amnioserosa cells, from cellularized blastoderm until the amnioserosa degenerates in late embryogenesis. FB FBgn0004863
4000 Ca-α1D &agr;1;&agr;1D;alpha1;alpha1D;BG:DS02795.1;Ca-&agr;1;Ca-&agr;1D;Ca-a1D;Ca-alpha1;Ca-_1D;Ca2+-channel &agr;1 subunit;calcium channel alpha-1 subunit;Ca[2+]-channel al;CG4894;DmCa1&agr;1;DmCa1alpha1;Dmca1D;DroCa1;Drosophila melanogaster calcium channel &agr;1 subunit DHP-sensitive;Drosophila melanogaster calcium channel alpha[[1]] subunit DHP-sensitive;l(2)35Fa;l35Fa Ca[2+]-channel protein α[[1]] subunit D fruit fly Drosophila melanogaster The D. melanogaster gene Ca2+-channel protein α1 subunit D, abbreviated as Ca-α1D, is reported here. It has also been known in FlyBase as Ca-α1. It encodes a product with voltage-gated calcium channel activity involved in muscle contraction which is a component of the voltage-gated calcium channel complex. It has been sequenced and its amino acid sequence contains a cation channels (non-ligand gated), a calcium and sodium channel pore region (S4-S6), a sodium channel, a EF-hand family, a calcium channel and a cation channels TM region (not potassium). It has been mapped cytologically to 35E5--6. It interacts genetically with Dfd. There are 8 recorded alleles: 1 in vitro construct (not available from the public stock centers), 6 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the wing, the longitudinal connective and the abdominal posterior fascicle and are recessive lethal. Ca-α1D is discussed in 56 references (excluding sequence accessions), dated between 1990 and 2003. These include at least one study of mutant phenotypes, 3 studies of wild-type function and 5 molecular studies. Among findings on Ca-α1D function, Ca-α1D is responsible for the dihyropyridine-sensitive channel in larval muscle but plays no role in the amiloride-sensitive current. FB FBgn0001991
4002 Ca-α2 Ca-&agr;2;Ca[2+]-channel-protein-alpha[[2]]-subunit;DmCa1&agr;2;DmCa1alpha2 Ca[2+]-channel-protein-α[[2]]-subunit fruit fly Drosophila melanogaster The D. melanogaster gene Ca2+-channel-protein-α2-subunit, abbreviated as Ca-α2, is reported here. It encodes a product with voltage-gated calcium channel activity which is a component of the voltage-gated calcium channel complex. There is one recorded allele, which is wild-type. Ca-α2 is discussed in 2 references, dated between 1995 and 1996. FB FBgn0015607
4003 Ca-β Ca-&bgr;;Calcium channel &bgr;;Calcium channel beta;calcium channel beta subunit;Ca[2+]-channel-protein-beta-subunit;CG6320;DmCa1&bgr;;DmCa1beta;dmcab1 Ca[2+]-channel-protein-β-subunit fruit fly Drosophila melanogaster The D. melanogaster gene Ca2+-channel-protein-β-subunit, abbreviated as Ca-β, is reported here. It has also been known in FlyBase as CG6320. It encodes a product with voltage-gated calcium channel activity involved in calcium ion transport which is a component of the voltage-gated calcium channel complex. It has been sequenced and its amino acid sequence contains a dihydropyridine sensitive L-type calcium channel, β subunit and a guanylate kinase. It has been mapped cytologically to 32D5--E1. There is one recorded allele, which is wild-type. Ca-β is discussed in 13 references (excluding sequence accessions), dated between 1995 and 2003. These include at least one molecular study. FB FBgn0015608
4007 Ca-P60A Ca-ATPase;Ca-p;Ca2+ATPase;calcium ATPase;CaP60A;Ca[2+]ATPase;CG3725;dSERCA;Kum;Kumbhakarna;l(2)k08308ab;l(2)k09025;organellar-type Ca-ATPase;sarco/endoplasmic reticulum-type Ca-2+-ATPase.;SERCA Calcium ATPase at 60A fruit fly Drosophila melanogaster The D. melanogaster gene Calcium ATPase at 60A, abbreviated as Ca-P60A, is reported here. It has also been known in FlyBase as CG3725, l(2)k08308a, l(2)k08308ab and l(2)k09025. It encodes a product with calcium-transporting ATPase activity (EC:3.6.3.8) involved in calcium ion transport which is a component of the endoplasmic reticulum membrane; it is expressed in the adult (adult central nervous system, cibarial muscle, ganglion cell, muscle and 6 other listed tissues). It has been sequenced and its amino acid sequence contains a haloacid dehalogenase/epoxide hydrolase family and a E1-E2 ATPases. It has been mapped cytologically to 60A11--12. It interacts genetically with N. There are 22 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 19 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the somatic clone eye and the somatic clone ommatidium and are larval recessive lethal. Ca-P60A is discussed in 26 references (excluding sequence accessions), dated between 1989 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 7 molecular studies. Among findings on Ca-P60A function, Ca-P60A is essential for cell viability and tissue morphogenesis during development. FB FBgn0004551
4008 Ca1G ;Dmca1G fruit fly Drosophila melanogaster The D. melanogaster gene Ca1G is reported here. It encodes a product with low voltage-gated calcium channel activity which is a component of the voltage-gated calcium channel complex. There is one recorded allele, which is wild-type. Ca1G is discussed in one reference, dating from 2000. FB FBgn0041343
4012 cac &agr;1A;13;alpha1A;Ca-&agr;1A;Ca-alpha1A;Cacophony;Calcium channel &agr;1 subunit, type A;CG1522;Dmc&agr;1A;Dmca1A;Dmcalpha1A;EE171;H18;H47;l(1)11Aa;l(1)13;l(1)L13;L13;lamina-deg;lamina-degeneration;ldg;ldg: lamina-degeneration;lethal(1)11Aa;nbA;nightblind;nightblind A;no-on-transient B;nonB;nonB: no-on-transient B;opm18;opm47;P18 cacophony fruit fly Drosophila melanogaster The D. melanogaster gene cacophony, abbreviated as cac, is reported here. It has also been known in FlyBase as Ca-α1A, l(1)11Aa and nbA. It encodes a product with voltage-gated calcium channel activity involved in calcium ion transport which is a component of the apical plasma membrane; it is expressed in the embryo (embryonic central nervous system). It has been sequenced and its amino acid sequence contains a cation channels (non-ligand gated), a calcium and sodium channel pore region (S4-S6), a sodium channel, a EF-hand family, a calcium channel and a cation channels TM region (not potassium). It has been mapped by recombination to 1-36.7 and cytologically to 10F8--11A1. It interacts genetically with comt and mle. There are 42 recorded alleles: 41 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the conditional ts dorsal medial muscle and are conditional ts paralytic, conditional ts (with cacTS2) paralytic and conditional ts neurophysiology defective. cac is discussed in 77 references (excluding sequence accessions), dated between 1971 and 2003. These include at least 11 studies of mutant phenotypes, 2 studies of wild-type function and 3 molecular studies. Among findings on cac mutants, cac mutants show complex complementation patterns and interactions. Among findings on cac function, the cac Ca channels mediate multiple, separable biological functions. FB FBgn0005563
4015 cad 38E.19;anon-WO2004063362.83;Cad;cd;CG1759;S67 caudal fruit fly Drosophila melanogaster The D. melanogaster gene caudal, abbreviated as cad, is reported here. It encodes a product with specific RNA polymerase II transcription factor activity involved in hindgut morphogenesis which is localized to the cytoplasm and the nucleus; it is expressed in the embryo (amnioproctodeal invagination, anal pad, embryonic anal pad, embryonic/larval hinddgut and 12 other listed tissues), larva (Malpighian tubule, female genital disc, genital disc, gonad and 2 other listed tissues) and ovary (unfertilized egg, egg chamber, nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors, a homeobox domain and a 'Homeobox' antennapedia-type domain. It has been mapped cytologically to 38E9--10. There are 20 recorded alleles: 13 in vitro constructs (none available from the public stock centers), 6 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the abdominal segment 9, the abdominal segment 10, the embryonic larval hindgut and 5 other listed tissues and are somatic clone visible. cad is discussed in 183 references (excluding sequence accessions), dated between 1985 and 2003. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function, one study of natural polymorphisms and 30 molecular studies. Among findings on cad mutants, cad mutants exhibit elimination of anal tuft and anal sense organs, additional lack of maternal product causes severe segmentation defects. Among findings on cad function, cad is essential for invagination of the hindgut primordium and for further specification and development of the hindgut. FB FBgn0000251
4016 Cad47B ;Cad49 fruit fly Drosophila melanogaster The D. melanogaster gene Cad47B is reported here. It has also been known in FlyBase as cad47B. It encodes a product involved in fasciculation of neuron which is a component of the integral to membrane. It has been mapped cytologically to 47B. There is one recorded allele, which is wild-type. Cad47B is discussed in 2 references, dated between 1997 and 1998. These include at least 2 studies of wild-type function. Among findings on Cad47B function, Cad47B encodes a member of the cadherin superfamily. FB FBgn0023454
4017 Cad74A ;Cad74B;CG6445;CT20086;DCad74B fruit fly Drosophila melanogaster The D. melanogaster gene Cad74A is reported here. It has also been known in FlyBase as CG6445. It encodes a product putatively involved in calcium-dependent cell-cell adhesion which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 74A5--6. There is one recorded allele, which is wild-type. Cad74A is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036715
4018 Cad87A ;CG6977;CT21611;DCad87A fruit fly Drosophila melanogaster The D. melanogaster gene Cad87A is reported here. It has also been known in FlyBase as CG6977. It encodes a product involved in calcium-dependent cell-cell adhesion which is a component of the integral to membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 87A1. There is one recorded allele, which is wild-type. Cad87A is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037963
4019 Cad88C ;CG3389;CT11389;DCad88C fruit fly Drosophila melanogaster The D. melanogaster gene Cad88C is reported here. It has also been known in FlyBase as CG3389. It encodes a product putatively involved in calcium-dependent cell-cell adhesion which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 88C10. There is one recorded allele, which is wild-type. Cad88C is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0038247
4020 Cad89D ;CG14900;CT34724;DCad89D fruit fly Drosophila melanogaster The D. melanogaster gene Cad89D is reported here. It has also been known in FlyBase as CG14900. It encodes a product involved in calcium-dependent cell-cell adhesion which is a component of the integral to membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 89B18. There is one recorded allele, which is wild-type. Cad89D is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038439
4021 Cad96Ca ;CG10239;CG10244;CT28779;DCad96Ca;DmHD-14;FGFR1-like;HD-14 fruit fly Drosophila melanogaster The D. melanogaster gene Cad96Ca is reported here. It has also been known in FlyBase as CG10244 and HD-14. It encodes a product with protein-tyrosine kinase activity (EC:2.7.1.112) involved in protein amino acid phosphorylation which is a component of the cellular_component unknown. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a tyrosine kinase catalytic domain and a cadherin domain. It has been mapped cytologically to 96C4--5. There is one recorded allele, which is wild-type. Cad96Ca is discussed in 16 references (excluding sequence accessions), dated between 1998 and 2003. These include at least one molecular study. FB FBgn0022800
4022 Cad96Cb ;CG10421;CT29262;DCad96Cb fruit fly Drosophila melanogaster The D. melanogaster gene Cad96Cb is reported here. It has also been known in FlyBase as CG10421. It encodes a product putatively involved in calcium-dependent cell-cell adhesion which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 96C7. There is one recorded allele, which is wild-type. Cad96Cb is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039294
4023 Cad99C CA-10;CG15511;CG31009;CG7805;CT35624;CT4930;DCad99C fruit fly Drosophila melanogaster The D. melanogaster gene Cad99C is reported here. It has also been known in FlyBase as CG15511 and CG7805. It encodes a product putatively involved in calcium-dependent cell-cell adhesion which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 99C4. There is one recorded allele, which is wild-type. Cad99C is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039709
4024 CadN anon-EST:CL32;B;Cadherin-N;CadherinN;CG7100;CT21941;D-cad;DN;DN-Cad;DN-Cadherin;Drosophila neuronal cadherin;l(2)36Da;l(2)Bld;lethal(2)36Da;N-cad;N-Cadherin;ncad;S(DmcycEJP)2.12 Cadherin-N fruit fly Drosophila melanogaster The D. melanogaster gene Cadherin-N, abbreviated as CadN, is reported here. It has also been known in FlyBase as anon-EST:CL32, anon-ESTCL32 and l(2)36Da. It encodes a product with beta-catenin binding involved in calcium-dependent cell-cell adhesion which is localized to the cytoplasm and the intercellular junction; it is expressed in the embryo (anterior commissure, axon, embryonic nervous system, embryonic neuron and 7 other listed tissues) and larva (adult myoblast, axon and neuropil). It has been sequenced and its amino acid sequence contains a cadherin cytoplasmic region, a calcium-binding EGF-like domain and a cadherin domain. It has been mapped by recombination to 2-53.1 and cytologically to 36D1--2. There are 13 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 10 classical mutants (1 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the longitudinal connective, the MP1 neuron, the vMP2 neuron and the medulla and are embryonic recessive lethal and somatic clone optomotor behavior defective. CadN is discussed in 65 references (excluding sequence accessions), dated between 1968 and 2003. These include at least one study of mutant phenotypes, 3 studies of wild-type function and 4 molecular studies. Among findings on CadN function, CadN has a role in regulating synaptic target specificity in the visual system. FB FBgn0015609
4025 CadN2 ;CG7527;CT23007;DmNCad2;DN-Cad2;DN-cadh-like;DN-like;N-Cad2;NCad2 fruit fly Drosophila melanogaster The D. melanogaster gene CadN2 is reported here. It has also been known in FlyBase as CG7527 and DN-Cad2. It encodes a product with putative cell adhesion molecule binding putatively involved in calcium-dependent cell-cell adhesion which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a cadherin cytoplasmic region, a calcium-binding EGF-like domain and a cadherin domain. It has been mapped cytologically to 36D3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CadN2 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032655
4026 Caf1 55;CAF-1;CAF1;caf1 p55;CAF1p55;CG4236;Chromatin assembly factor 1;d-CAF1;dCAF-1;dCAF-1 p55;dNURF;MSI1/RbAp48/CAC3/LIN-53;Nucleosome remodeling factor;Nucleosome remodeling factor - 55kD;NURF;NURF-55;NURF55;NURF: Nucleosome remodeling factor;p55;p55,CAF1;p55/NURF-55 Chromatin assembly factor 1 subunit fruit fly Drosophila melanogaster The D. melanogaster gene Chromatin assembly factor 1 subunit, abbreviated as Caf1, is reported here. It has also been known in FlyBase as Nurf-55. It encodes a product with histone deacetylase binding involved in DNA repair which is localized to the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 88E3. There is one recorded allele, which is wild-type. Caf1 is discussed in 82 references (excluding sequence accessions), dated between 1995 and 2003. These include at least 6 studies of wild-type function and 5 molecular studies. FB FBgn0015610
4027 Caf1-105 Caf1-10;CG12892 fruit fly Drosophila melanogaster The D. melanogaster gene Caf1-105 is reported here. It has also been known in FlyBase as CG12892. It encodes a product with DNA binding involved in chromatin assembly/disassembly which is a component of the chromatin assembly complex. It has been sequenced and its amino acid sequence contains a beta G-protein (transducin). It has been mapped cytologically to 47A9. There is one recorded allele, which is wild-type. Caf1-105 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033526
4028 Caf1-180 ;CG12109;p180 fruit fly Drosophila melanogaster The D. melanogaster gene Caf1-180 is reported here. It has also been known in FlyBase as CG12109. It encodes a product with histone-specific chaperone activity involved in nucleosome assembly which is a component of the chromatin assembly complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7F8. There is one recorded allele, which is wild-type. Caf1-180 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030054
4038 cals Cad102F;calsyntenin-1;CG11059;CT30877;DCad102F calsyntenin-1 fruit fly Drosophila melanogaster The D. melanogaster gene calsyntenin-1, abbreviated as cals, is reported here. It has also been known in FlyBase as CG11059 and calsyntenin-1. It encodes a product with calcium ion binding involved in synaptic transmission which is a component of the extracellular. It has been sequenced and its amino acid sequence contains a cadherin domain. It has been mapped cytologically to 102D4. There is one recorded allele, which is wild-type. cals is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039928
4039 Calx 9C5;anon-93ABa;CALX1.1;CG5685;Dmel/Ncx;NCX Na/Ca-exchange protein fruit fly Drosophila melanogaster The D. melanogaster gene Na/Ca-exchange protein, abbreviated as Calx, is reported here. It has also been known in FlyBase as Ncx and anon-93ABa. It encodes a product with calcium:sodium antiporter activity putatively involved in cation transport which is a component of the plasma membrane; it is expressed in the adult (adult brain, adult head, optic nerve and retina). It has been sequenced and its amino acid sequence contains a sodium/calcium exchanger domain. It has been mapped cytologically to 93B2--3. There is one recorded allele, which is wild-type. Calx is discussed in 28 references (excluding sequence accessions), dated between 1989 and 2003. These include at least 4 studies of wild-type function and 3 molecular studies. Among findings on Calx function, heterologous expression of Calx in Xenopus oocytes shows that it encodes a bona fide sodium-calcium exchanger; unlike mammalian retinal exchangers, it does not depend on potassium for activity. FB FBgn0013995
4040 Cam 3909;anon-EST:Posey59;Cal;Cal49A;calmodulin;CAM;CG8472;D-CaM;dCaM;DmCalm;l(2)03909;l(2)3909 Calmodulin fruit fly Drosophila melanogaster The D. melanogaster gene Calmodulin, abbreviated as Cam, is reported here. It has also been known in FlyBase as Cal and l(2)03909. It encodes a product with calcium ion binding involved in metarhodopsin inactivation which is a component of the rhabdomere; it is expressed in the adult (adult head) and embryo (anterior embryonic/larval midgut, embryonic central nervous system, peripheral nervous system and posterior embryonic/larval midgut). It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 48F1--6. It interacts genetically with l(2)C43. There are 33 recorded alleles: 8 in vitro constructs (4 available from the public stock centers), 24 classical mutants (8 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the ectopic wing vein, the (with Cam7) pupa and the pupal (with Cam7) adult head and are larval recessive lethal, larval behavioral, recessive visual behavior defective, locomotor behavior defective, flight behavior defective, (with Cam3c1) uncoordinated, (with Cam3c1) neuroanatomy defective and (with Cam7) lethal. Cam is discussed in 134 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 17 studies of mutant phenotypes, 2 studies of wild-type function and 10 molecular studies. Among findings on Cam mutants, the spontaneous avoidance behavior of Cam null mutants has striking similarities to the enhanced avoidance response produced by some calmodulin mutations in Paramecium. Among findings on Cam function, Cam protein coordinates termination of the light response in photoreceptor cells by modulating receptor and ion channel activity. FB FBgn0000253
4043 can ;CG6577;dmTAF5b;dTAF5L;dTAFII80;dTAF[[II]]80;TAF5L cannonball fruit fly Drosophila melanogaster The D. melanogaster gene cannonball, abbreviated as can, is reported here. It has also been known in FlyBase as CG6577. It encodes a product with general RNA polymerase II transcription factor activity involved in transcription initiation from Pol II promoter which is a component of the transcription factor TFIID complex. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 3-31 and cytologically to 67D12. It interacts genetically with twe. There are 18 recorded alleles: 16 classical mutants (none available from the public stock centers) and 2 wild-type. Loss-of-function mutations have been isolated which affect the testis and the spermatocyte and are recessive male sterile and recessive meiotic. can is discussed in 36 references (excluding sequence accessions), dated between 1993 and 2003. These include at least 2 studies of mutant phenotypes and 2 studies of wild-type function. Among findings on can function, can is required for spermatid differentiation. FB FBgn0011569
4044 cana ;CENP-ana;CENP-E ana;CG32955;CG33694;CG4831;CP15516;DmCana;KIF10;l(2)k07716 CENP-ana fruit fly Drosophila melanogaster The D. melanogaster gene CENP-ana, abbreviated as cana, is reported here. It has also been known in FlyBase as CG4831 and l(2)k07716. It encodes a product with plus-end-directed microtubule motor activity (EC:3.6.4.4) involved in mitotic anaphase which is a component of the kinesin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 32E2. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. cana is discussed in 13 references (excluding sequence accessions), dated between 1994 and 2002. These include at least 2 molecular studies. FB FBgn0040233
4050 Cap ;CG9802;DmSMC3;DmSMC3/Cap;SMC3 Chromosome-associated protein fruit fly Drosophila melanogaster The D. melanogaster gene Chromosome-associated protein, abbreviated as Cap, is reported here. It encodes a product with putative chromatin binding involved in sister chromatid cohesion which is a component of the cohesin complex. It has been sequenced and its amino acid sequence contains a SMC domain N terminal domain, a SMC family, C-terminal domain and a ABC transporter. It has been mapped cytologically to 14F1. There is one recorded allele, which is wild-type. Cap is discussed in 13 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 2 molecular studies. FB FBgn0015615
4051 CAP ;CG18408;CG18409;CG3451;DCAP;Rexin fruit fly Drosophila melanogaster The D. melanogaster gene CAP is reported here. It has also been known in FlyBase as CG18408, CG18409, CG3451 and rexin. It encodes a product with vinculin binding putatively involved in MAPKKK cascade which is a component of the focal adhesion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46F9--47A1. There are 8 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 3 classical mutants (2 available from the public stock centers) and 1 wild-type. CAP is discussed in 12 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0033504
4052 Cap-G BcDNA:RH49308;CapG;CG13327;CG13328;CG17054;CG30057;DCAP-G;l(2)c00093;lethal (2) c00093 fruit fly Drosophila melanogaster The D. melanogaster gene Cap-G is reported here. It has also been known in FlyBase as BcDNA:RH49308, CG13327, CG17054 and CG30057. It encodes a product involved in mitotic chromosome segregation which is a component of the condensin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 49F2--4. There is one recorded allele, which is wild-type. Cap-G is discussed in 10 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0033795
4054 capaR capa receptor;CG14575 capa receptor fruit fly Drosophila melanogaster The D. melanogaster gene capa receptor, abbreviated as capaR, is reported here. It has also been known in FlyBase as CG14575. It encodes a product with G-protein coupled receptor activity involved in fluid secretion which is a component of the integral to membrane. It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily. It has been mapped cytologically to 78D6. There is one recorded allele, which is wild-type. capaR is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037100
4060 cas bad;BcDNA:LD14270;bladderwrack;Cas;cass;Castor;CG13281;CG2102;dcas;l(2)k03902;l(3)j1C2;l(3)neo33;ming castor fruit fly Drosophila melanogaster The D. melanogaster gene castor, abbreviated as cas, is reported here. It has also been known in FlyBase as CG2102, l(3)neo33 and ming. It encodes a product with RNA polymerase II transcription factor activity involved in mushroom body development which is a component of the nucleus; it is expressed in the embryo (central nervous system, embryonic central nervous system, ganglion mother cell, midline and 13 other listed tissues). It has been sequenced and its amino acid sequence contains a HMG-I and HMG-Y DNA-binding domain (A+T-hook) and a zinc finger, C2H2 type. It has been mapped cytologically to 83C1. It interacts genetically with drl and nob. There are 17 recorded alleles: 1 in vitro construct (not available from the public stock centers), 15 classical mutants (1 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic central nervous system and are embryonic recessive lethal. cas is discussed in 85 references (excluding sequence accessions), dated between 1988 and 2004. These include at least 6 studies of mutant phenotypes, one study of wild-type function and 3 molecular studies. Among findings on cas function, cas is involved in post-embryonic brain development. FB FBgn0004878
4061 Cas BcDNA:LD14270;CAS;CAS/CSE1 segregation protein;CG13281;Dcas;l(2)k03902 CAS/CSE1 segregation protein fruit fly Drosophila melanogaster The D. melanogaster gene CAS/CSE1 segregation protein, abbreviated as Cas, is reported here. It has also been known in FlyBase as BcDNA:LD14270, CAS and l(2)k03902. It encodes a product with importin-alpha export receptor activity involved in protein-nucleus export which is a component of the nucleus. It has been sequenced and its amino acid sequence contains an importin-β N-terminal domain. It has been mapped cytologically to 36B1--2. There are 10 recorded alleles: 1 in vitro construct (not available from the public stock centers), 8 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the egg, the microchaeta, the macrochaeta and 3 other listed tissues and are conditional ts lethal. Cas is discussed in 13 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one study of wild-type function and 5 molecular studies. Among findings on Cas function, Cas is a ubiquitous export receptor that seems to be required in all tissues. FB FBgn0022213
4064 Cat bs36h11.y1;CAT;CATA;catalase;CATHPO;CG6871;CT21282;cytosolic catalase;DMCATHPO;DROCATHPO;l(3)neo26;U00145 Catalase fruit fly Drosophila melanogaster The D. melanogaster gene Catalase, abbreviated as Cat, is reported here. It has also been known in FlyBase as MS:DROCATHPO and l(3)neo26. It encodes a product with catalase activity (EC:1.11.1.6) involved in determination of adult life span which is a component of the peroxisome; it is expressed in the larva (dorsal mesothoracic disc). It has been sequenced and its amino acid sequence contains a catalase. It has been mapped by recombination to 3-47.0 and cytologically to 75E1. There are 15 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 10 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which are chemical sensitive and recessive lethal. Cat is discussed in 93 references (excluding sequence accessions), dated between 1977 and 2003. These include at least 7 studies of mutant phenotypes, 3 studies of wild-type function and 8 molecular studies. Among findings on Cat function, overexpression of Cat significantly increases resistance to hydrogen peroxide but has neutral or slightly deleterious effects on adult life span. FB FBgn0000261
4066 cato Cato;CG7760;cousin of atonal;DATH-B;Drosophila atonal homologue cousin of atonal fruit fly Drosophila melanogaster The D. melanogaster gene cousin of atonal, abbreviated as cato, is reported here. It encodes a product with transcription factor activity involved in sensory organ development which is a component of the nucleus; it is expressed in the embryo (P cell, chordotonal organ precursor cell, embryonic peripheral nervous system, external sensory organ precursor cell and sensory organ precursor cell) and larva (imaginal disc, peripheral nervous system and sensory organ precursor cell). It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain. It has been mapped cytologically to 53A4. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. cato is discussed in 11 references (excluding sequence accessions), dated between 1998 and 2003. These include at least one study of wild-type function and 3 molecular studies. Among findings on cato function, cato is involved in sensory neuron morphology. FB FBgn0024249
4067 Catsup Bc;CG10449;dCATSUP;fs(2)ltoQT50;l(2)37Bc;l(2)E13;l(2)k05402;l(2)k05424 Catecholamines up fruit fly Drosophila melanogaster The D. melanogaster gene Catecholamines up, abbreviated as Catsup, is reported here. It has also been known in FlyBase as CG10449 and l(2)k05424. It encodes a product involved in regulation of catecholamine metabolism which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-53.9 and cytologically to 37B11. There are 60 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 54 classical mutants (2 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the adult cuticle, the eye, the macrochaeta and 6 other listed tissues and are pupal recessive lethal, recessive semi-lethal, recessive female sterile and dominant melanotic 'tumor'. Catsup is discussed in 34 references (excluding sequence accessions), dated between 1976 and 2003. These include at least 3 studies of mutant phenotypes and 6 molecular studies. Among findings on Catsup mutants, mutations in Catsup exhibit morphological defects of the cuticle. FB FBgn0002022
4068 caup ;CG10605;iro;iro-C;Iroquis complex;iroquois;iroquois gene complex;iroquois-complex caupolican fruit fly Drosophila melanogaster The D. melanogaster gene caupolican, abbreviated as caup, is reported here. It has also been known in FlyBase as iro. It encodes a product with transcription regulator activity involved in regulation of transcription from Pol II promoter which is a component of the nucleus; it is expressed in the embryo (embryonic/larval proventriculus, epidermis and procephalic segment) and larva (alula, dorsal metathoracic disc, imaginal disc, larval ventral ganglion and 5 other listed tissues). It has been sequenced and its amino acid sequence contains a homeobox domain and an iroquois-class homeodomain protein motif. It has been mapped cytologically to 69D1. It interacts genetically with N and dally. There are 11 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 8 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the macrochaeta, the microchaeta, the mesothoracic segment and 3 other listed tissues and are viable, visible, recessive female sterile and recessive male sterile. caup is discussed in 88 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 6 studies of mutant phenotypes, 5 studies of wild-type function and 5 molecular studies. FB FBgn0015919
4069 cav 1G5;anon fe 1G5;anon-EST:fe1G5;anon-EST:fe1G5: anon-fast-evolving-1G5;anon-fast-evolving-1G5;anon1G5;anonymous fast evolving gene IG5;caravaggio;CG6219;Hoap;HP1/ORC-associated protein;p55 caravaggio fruit fly Drosophila melanogaster The D. melanogaster gene caravaggio, abbreviated as cav, is reported here. It has also been known in FlyBase as CG6219, Hoap, anon-1G5, anon-EST:fe1G5 and anon-fe1G5. It encodes a product with satellite DNA binding involved in telomere capping which is a component of the chromosome, telomeric region. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95F2. There are 3 recorded alleles: 1 in vitro construct (not available from the public stock centers), 1 classical mutant (not available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the mitotic metaphase, the metaphase chromosome and the telomere and are recessive lethal and mitotic. cav is discussed in 22 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one study of mutant phenotypes, one study of natural polymorphisms and 2 molecular studies. FB FBgn0026257
4070 caz anon-Pen19;BcDNA:GM09207;cas;CG3606;p19;pen19;Sarcoma-associated RNA-binding fly homolog;SARFH;Sarfh: Sarcoma-associated RNA-binding fly homolog;TFIID cabeza fruit fly Drosophila melanogaster The D. melanogaster gene cabeza, abbreviated as caz, is reported here. It has also been known in FlyBase as BcDNA:GM09207 and anon-Pen19. It encodes a product with general RNA polymerase II transcription factor activity involved in transcription initiation from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 14B10. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. caz is discussed in 21 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 3 studies of mutant phenotypes and 2 molecular studies. FB FBgn0011571
4074 CBP BcDNA.GH12350;BcDNA:GH12350;Ca2+ - binding protein;CG1435 sarcoplasmic calcium-binding protein fruit fly Drosophila melanogaster The D. melanogaster gene sarcoplasmic calcium-binding protein, abbreviated as CBP, is reported here. It encodes a product with calcium ion binding which is a component of the sarcoplasmic reticulum. It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 7B2. There are 4 recorded alleles: 3 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. CBP is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0026144
4075 Cbp20 CBP20;CG12357 cap binding protein 20 fruit fly Drosophila melanogaster The D. melanogaster gene cap binding protein 20, abbreviated as Cbp20, is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 90F4. There is one recorded allele, which is wild-type. Cbp20 is discussed in 13 references (excluding sequence accessions), dated between 1997 and 2003. These include at least 2 molecular studies. FB FBgn0022943
4078 Cbp80 CBP80;CG7035;EG:84H4.3 cap binding protein 80 fruit fly Drosophila melanogaster The D. melanogaster gene cap binding protein 80, abbreviated as Cbp80, is reported here. It has also been known in FlyBase as EG:84H4.3. It encodes a product with RNA cap binding involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNA cap binding complex. It has been sequenced and its amino acid sequence contains a middle domain of eIF4G. It has been mapped cytologically to 4C11. There is one recorded allele, which is wild-type. Cbp80 is discussed in 14 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one molecular study. FB FBgn0022942
4081 Cbs CBS;dem;dementin Calcium-binding protein in Shaker fruit fly Drosophila melanogaster The D. melanogaster gene Calcium-binding protein in Shaker, abbreviated as Cbs, is reported here. It encodes a product with calcium ion binding. It has been mapped by recombination to 1-57.6 and cytologically to 16F1--3. There is one recorded allele, which is wild-type. Cbs is discussed in 3 references, dated between 1989 and 1991. FB FBgn0004616
4085 CcapR anon-WO0170980.46;anon-WO0170980.47;Cardioacceleratory peptide receptor;CG14547;CG33344;CG6111;DCCAPR Cardioacceleratory peptide receptor fruit fly Drosophila melanogaster The D. melanogaster gene Cardioacceleratory peptide receptor, abbreviated as CcapR, is reported here. It has also been known in FlyBase as CG14547 and CG6111. It encodes a product with peptide receptor activity involved in G-protein coupled receptor protein signaling pathway which is putatively a component of the integral to membrane. It has been sequenced and its amino acid sequence contains a rhodopsin-like GPCR superfamily and a vasopressin receptor. It has been mapped cytologically to 96F8. There is one recorded allele, which is wild-type. CcapR is discussed in 14 references (excluding sequence accessions), dated between 1999 and 2004. FB FBgn0039396
4096 CCR4 BEST:GH20274;CG17741;CG31137;CG5534;CT33003;CT39331;twin;twn fruit fly Drosophila melanogaster The D. melanogaster gene CCR4 is reported here. It has also been known in FlyBase as CG17741 and CG5534. It encodes a product with transcription regulator activity involved in regulation of transcription from Pol II promoter which is a component of the cytoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95F1--2. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CCR4 is discussed in 12 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039168
4104 cdc16 ;CG6759;Dmcdc16 fruit fly Drosophila melanogaster The D. melanogaster gene cdc16 is reported here. It encodes a product with ubiquitin-protein ligase activity (EC:6.3.2.19) involved in ubiquitin cycle which is a component of the anaphase-promoting complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 94E9. There is one recorded allele, which is wild-type. cdc16 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0025781
4105 cdc2 cdc;CDC2;Cdc2 kinase;cdc2Dm;CDCDm;CDK1;CDK1/CDC2;CG5363;Dcdc2;Dm cdc2;Dmcdc2;DmCdk1;group 4;l(2)31Eh cdc2 fruit fly Drosophila melanogaster The D. melanogaster gene cdc2 is reported here. It encodes a product with protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle which is a component of the nucleus; it is expressed in the embryo (embryonic central nervous system). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 31D11. It interacts genetically with CycA, CycB, Cdc37, esg, Myb and 7 other listed genes. There are 25 recorded alleles: 13 in vitro constructs (1 available from the public stock centers), 11 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the larval imaginal disc, the larval brain, the central nervous system and 9 other listed tissues and are recessive lethal. cdc2 is discussed in 155 references (excluding sequence accessions), dated between 1990 and 2003. These include at least 24 studies of mutant phenotypes, one study of wild-type function and 9 molecular studies. Among findings on cdc2 mutants, preliminary genetic and molecular analysis of mutations of cdc2. Among findings on cdc2 function, neural progenitor asymmetric divisions require cdc2. FB FBgn0004106
4111 CDC45L anon-1Ec;Cdc45;CG3658;D;DmCdc45;EG:BACR7A4.11;Transcription unit D fruit fly Drosophila melanogaster The D. melanogaster gene CDC45L is reported here. It has also been known in FlyBase as anon-1Ec. It encodes a product with DNA binding involved in DNA replication which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a CDC45-like domain. It has been mapped cytologically to 1E1. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. CDC45L is discussed in 15 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 4 molecular studies. FB FBgn0026143
4116 Cdk5α Cdk5&agr;;Cdk5a;CG5387;dCdk5&agr;;dCdk5alpha;Dp35;p35;p35-31C Cdk5 activator-like protein fruit fly Drosophila melanogaster The D. melanogaster gene Cdk5 activator-like protein, abbreviated as Cdk5α, is reported here. It has also been known in FlyBase as Cdk5a and p35-31C. It encodes a product with cyclin-dependent protein kinase 5 activator regulator activity putatively involved in protein amino acid phosphorylation which is a component of the cyclin-dependent protein kinase 5 activator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 31D3--4. It interacts genetically with Cdk5. There are 3 recorded alleles: 2 in vitro constructs (none available from the public stock centers) and 1 wild-type. Cdk5α is discussed in 12 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0027491
4117 Cdk7 CDK7;CG3319;DmCDK7;DmMO15;p40MO15;p40[MO15] Cyclin-dependent kinase 7 fruit fly Drosophila melanogaster The D. melanogaster gene Cyclin-dependent kinase 7, abbreviated as Cdk7, is reported here. It encodes a product with protein serine/threonine kinase activity involved in transcription initiation from Pol II promoter which is a component of the transcription factor TFIIH complex; it is expressed in the adult (ovary). It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 4F4. It interacts genetically with twe and hay. There are 17 recorded alleles: 14 in vitro constructs (2 available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which are conditional ts somatic clone mitotic. Cdk7 is discussed in 23 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 2 studies of mutant phenotypes, 3 studies of wild-type function and one molecular study. Among findings on Cdk7 function, Cdk7 probably has a role in the control of the transcriptional machinery. FB FBgn0015617
4118 Cdk8 CDK8;CG10572;Cyclin-dependent kinase 8;DmCdk8;dTRAP56;p58 Cyclin-dependent kinase 8 fruit fly Drosophila melanogaster The D. melanogaster gene Cyclin-dependent kinase 8, abbreviated as Cdk8, is reported here. It encodes a product with cyclin-dependent protein kinase activity (EC:2.7.1.-) involved in protein amino acid phosphorylation which is putatively a component of the mediator complex. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 67C10. There is one recorded allele, which is wild-type. Cdk8 is discussed in 13 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 2 studies of wild-type function and 3 molecular studies. FB FBgn0015618
4119 Cdk9 CDK9;CG5179;Cyclin-dependent kinase9 2.7;P-TEF;P-TEFb;p43 PITALRE;Positive transcription elongation factor b;Positive transcription elongation factor b, small subunit;PTefb;small subunit Cyclin-dependent kinase 9 fruit fly Drosophila melanogaster The D. melanogaster gene Cyclin-dependent kinase 9, abbreviated as Cdk9, is reported here. It has also been known in FlyBase as PTefb. It encodes a product with cyclin-dependent protein kinase activity (EC:2.7.1.-) involved in protein amino acid phosphorylation which is a component of the nucleus. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 58F3. There are 7 recorded alleles: 6 in vitro constructs (none available from the public stock centers) and 1 wild-type. Cdk9 is discussed in 25 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 3 studies of wild-type function and 9 molecular studies. Among findings on Cdk9 function, Cdk9 encodes the small subunit of P-TEFb (positive transcription elongation factor b). FB FBgn0019949
4120 Cdlc2 8kd dynein light chain;anon-WO0140519.117;CG5450;cytoplasmic dynein;dlc;dynein Cytoplasmic dynein light chain 2 fruit fly Drosophila melanogaster The D. melanogaster gene Cytoplasmic dynein light chain 2, abbreviated as Cdlc2, is reported here. It encodes a product with motor activity putatively involved in microtubule-based movement which is a component of the cytoplasmic dynein complex. It has been sequenced and its amino acid sequence contains a dynein light chain type 1. It has been mapped cytologically to 22A1. There is one recorded allele, which is wild-type. Cdlc2 is discussed in 11 references (excluding sequence accessions), dated between 1996 and 2003. These include at least 4 molecular studies. FB FBgn0026141
4121 CdsA CDP-DAG synthase;CDP-diacylglycerol synthetase;CDS;CG7962;eye-CDS;winded CDP diglyceride synthetase fruit fly Drosophila melanogaster The D. melanogaster gene CDP diglyceride synthetase, abbreviated as CdsA, is reported here. It has also been known in FlyBase as CG7962. It encodes a product with phosphatidate cytidylyltransferase activity (EC:2.7.7.41) involved in rhodopsin mediated signaling which is a component of the nuclear membrane; it is expressed in the adult (adult head, ocellus and photoreceptor cell R1 to 8). It has been sequenced and its amino acid sequence contains a phosphatidate cytidylyltransferase. It has been mapped cytologically to 66B7. There are 5 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the photoreceptor cell R1 to 8 and the photoreceptor cell and are visual behavior defective and neurophysiology defective. CdsA is discussed in 23 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 2 studies of mutant phenotypes and 3 molecular studies. FB FBgn0010350
4129 cenG1A BG:DS08220.1;centaurin gamma 1A;CG16866;CG16867;CG31811;CG7982 centaurin γ 1A fruit fly Drosophila melanogaster The D. melanogaster gene centaurin gamma 1A, abbreviated as cenG1A, is reported here. It has also been known in FlyBase as BG:DS08220.1, BcDNA:LD11783, CG16866 and CG16867. It encodes a product with ARF GTPase activator activity involved in small GTPase mediated signal transduction which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc-finger GCS-type, a ras GTPase superfamily and a small GTPase, Ras subfamily. It has been mapped cytologically to 34D6--E2. There are 4 recorded alleles: 3 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which are viable. cenG1A is discussed in 18 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 4 molecular studies. FB FBgn0028509
4131 Cf2 BcDNA:GM09668;CF2;CF2.5;CG11924 Chorion factor 2 fruit fly Drosophila melanogaster The D. melanogaster gene Chorion factor 2, abbreviated as Cf2, is reported here. It has also been known in FlyBase as BcDNA:GM09668. It encodes a product with RNA polymerase II transcription factor activity involved in regulation of transcription, DNA-dependent which is localized to the nucleus; it is expressed in the adult (testis) and ovary (egg chamber, follicle cell and ovary). It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 25B1. It interacts genetically with fs(1)K10 and spir. There are 12 recorded alleles: 11 in vitro constructs (none available from the public stock centers) and 1 wild-type. Cf2 is discussed in 42 references (excluding sequence accessions), dated between 1990 and 2003. These include at least 3 studies of wild-type function and 6 molecular studies. Among findings on Cf2 function, Cf2 protein functions as a repressor of dorsally expressed genes. FB FBgn0000286
4132 CFDD ;Common regulatory Factor for DNA replication and DREF genes Common regulatory Factor for DNA replication and DREF genes fruit fly Drosophila melanogaster The D. melanogaster gene Common regulatory Factor for DNA replication and DREF genes, abbreviated as CFDD, is reported here. It encodes a product with DNA binding which is a component of the nucleus. There is one recorded allele, which is wild-type. CFDD is discussed in one reference, dating from 1997. FB FBgn0022945
4133 cg ;CG8367;comb gap;l(2)07659;l(2)k11504;mig;migraine combgap fruit fly Drosophila melanogaster The D. melanogaster gene combgap, abbreviated as cg, is reported here. It has also been known in FlyBase as CG8367, l(2)07659 and mig. It encodes a product with transcription factor activity involved in wing morphogenesis which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped by recombination to 2-71.1 and cytologically to 50E1. It interacts genetically with en, ci, ds, d, fj and 5 other listed genes. There are 19 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 10 classical mutants (3 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the anterior compartment ventral thoracic disc, the (with cg1) wing vein L4, the supernumerary (with cg1) sex comb and 10 other listed tissues and are semi-lethal, (with cg1) visible and recessive lethal. cg is discussed in 40 references (excluding sequence accessions), dated between 1949 and 2003. These include at least 14 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on cg mutants, mutations in cg cause pleiotropic phenotypes in embryonic patterns and affect several longitudinal veins. Among findings on cg function, cg is required for the establishment of radial pattern. FB FBgn0000289
4145 CG10101 ;CT28433 fruit fly Drosophila melanogaster The D. melanogaster gene CG10101 is reported here. It encodes a product with inotropic glutamate receptor activity. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 84D6. There is one recorded allele, which is wild-type. CG10101 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037501
4155 CG10166 fruit fly Drosophila melanogaster The D. melanogaster gene CG10166 is reported here. It encodes a product with dolichyl-phosphate beta-D-mannosyltransferase activity (EC:2.4.1.83) involved in protein amino acid glycosylation which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence contains a glycosyl transferase, family 2. It has been mapped cytologically to 37E5. There is one recorded allele, which is wild-type. CG10166 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0032799
4169 CG10214 fruit fly Drosophila melanogaster The D. melanogaster gene CG10214 is reported here. It encodes a product with oligonucleotidase activity (EC:3.1.13.3) putatively involved in RNA catabolism which is a component of the nucleus. It has been sequenced and its amino acid sequence contains an exonuclease. It has been mapped cytologically to 95B1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10214 is discussed in 7 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039115
4170 CG10219 BEST:GH27735 fruit fly Drosophila melanogaster The D. melanogaster gene CG10219 is reported here. It encodes a product with succinate dehydrogenase (ubiquinone) activity (EC:1.3.5.1) involved in tricarboxylic acid cycle which is a component of the respiratory chain complex II (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95B1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10219 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0039112
4171 CG10221 BcDNA:LD23587 fruit fly Drosophila melanogaster The D. melanogaster gene CG10221 is reported here. It has also been known in FlyBase as BcDNA:LD23587. It encodes a product which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95B1. There is one recorded allele, which is wild-type. CG10221 is discussed in 2 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0028475
4173 CG10228 fruit fly Drosophila melanogaster The D. melanogaster gene CG10228 is reported here. It encodes a product involved in mRNA cleavage which is a component of the mRNA cleavage factor complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 51C5--7. There is one recorded allele, which is wild-type. CG10228 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0033975
4185 CG10296 ;FAX-1;NR2E5 fruit fly Drosophila melanogaster The D. melanogaster gene CG10296 is reported here. It encodes a product with steroid hormone receptor activity putatively involved in lipid metabolism which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a vitamin D receptor, a ligand-binding domain of nuclear hormone receptor and a C4-type steroid receptor zinc finger. It has been mapped cytologically to 83E4. There is one recorded allele, which is wild-type. CG10296 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037436
4189 CG10320 anon-EST:Posey47;anon-EST:Posey84 fruit fly Drosophila melanogaster The D. melanogaster gene CG10320 is reported here. It has also been known in FlyBase as anon-EST:Posey47 and anon-EST:Posey84. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 57F6. There is one recorded allele, which is wild-type. CG10320 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034645
4190 CG10326 fruit fly Drosophila melanogaster The D. melanogaster gene CG10326 is reported here. It encodes a product which is putatively a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 89D6. There is one recorded allele, which is wild-type. CG10326 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0038453
4191 CG10333 ;DmRH19 fruit fly Drosophila melanogaster The D. melanogaster gene CG10333 is reported here. It encodes a product with ATP dependent RNA helicase activity involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a ATP-dependent helicase, DEAD-box, a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 36F7. There is one recorded allele, which is wild-type. CG10333 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032690
4194 CG10345 BcDNA;BcDNA:GH08773 fruit fly Drosophila melanogaster The D. melanogaster gene CG10345 is reported here. It has also been known in FlyBase as BcDNA:GH08773. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a CD36 family. It has been mapped cytologically to 89D5. There is one recorded allele, which is wild-type. CG10345 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0027562
4198 CG10361 fruit fly Drosophila melanogaster The D. melanogaster gene CG10361 is reported here. It encodes a product with glycine C-acetyltransferase activity (EC:2.3.1.29) involved in amino acid metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an aminotransferases class-II. It has been mapped cytologically to 68E1. There is one recorded allele, which is wild-type. CG10361 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036208
4202 CG10396 BcDNA:AT07685;IV;IV: transcript group IV fruit fly Drosophila melanogaster The D. melanogaster gene CG10396 is reported here. It has also been known in FlyBase as BcDNA:AT07685. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 41F3. There is one recorded allele, which is wild-type. CG10396 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033020
4203 CG10399 fruit fly Drosophila melanogaster The D. melanogaster gene CG10399 is reported here. It encodes a product with hydroxymethylglutaryl-CoA lyase activity (EC:4.1.3.4) involved in leucine metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a HMG-CoA Lyase-like family. It has been mapped cytologically to 27C7. There is one recorded allele, which is wild-type. CG10399 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031877
4205 CG1041 fruit fly Drosophila melanogaster The D. melanogaster gene CG1041 is reported here. It encodes a product with carnitine O-acetyltransferase activity (EC:2.3.1.7) putatively involved in amino acid metabolism which is a component of the peroxisome. It has been sequenced and its amino acid sequence contains an acyltransferase ChoActase / COT / CPT family. It has been mapped cytologically to 83E4. There is one recorded allele, which is wild-type. CG1041 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037440
4208 CG10418 BcDNA:GM14851 fruit fly Drosophila melanogaster The D. melanogaster gene CG10418 is reported here. It has also been known in FlyBase as BcDNA:GM14851. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a small nuclear ribonucleoprotein (Sm protein). It has been mapped cytologically to 69B2. There is one recorded allele, which is wild-type. CG10418 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036277
4209 RpS27 anon-EST:Posey295;CG10423 fruit fly Drosophila melanogaster The D. melanogaster gene RpS27 is reported here. It has also been known in FlyBase as CG10423, anon-EST:Posey295 and anon-ESTPosey295. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is putatively a component of the ribosome. It has been sequenced and its amino acid sequence contains a ribosomal protein S27E. It has been mapped cytologically to 96C8. There is one recorded allele, which is wild-type. RpS27 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0039300
4214 CG10445 fruit fly Drosophila melanogaster The D. melanogaster gene CG10445 is reported here. It encodes a product with Pol II transcription termination factor activity putatively involved in regulation of transcription from Pol II promoter. It has been sequenced and its amino acid sequence contains a SNF2 related domain, a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 84E5. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10445 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037531
4215 CG10447 BcDNA:RH50436 fruit fly Drosophila melanogaster The D. melanogaster gene CG10447 is reported here. It has also been known in FlyBase as BcDNA:RH50436. It encodes a product with transcription factor activity involved in transcription which is a component of the CCAAT-binding factor complex. It has been sequenced and its amino acid sequence contains a histone-fold/TFIID-TAF/NF-Y domain. It has been mapped cytologically to 38A2. There is one recorded allele, which is wild-type. CG10447 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032816
4221 CG10473 CG10437 fruit fly Drosophila melanogaster The D. melanogaster gene CG10473 is reported here. It encodes a product putatively involved in apoptosis which is putatively a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 37B11--12. There is one recorded allele, which is wild-type. CG10473 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032745
4225 CG10478 ;CG11040;g7295403 fruit fly Drosophila melanogaster The D. melanogaster gene CG10478 is reported here. It encodes a product with protein carrier activity involved in protein-nucleus import which is a component of the nuclear pore. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 65A2. There is one recorded allele, which is wild-type. CG10478 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035657
4227 CG10489 fruit fly Drosophila melanogaster The D. melanogaster gene CG10489 is reported here. It encodes a product with epsilon DNA polymerase activity putatively involved in DNA repair which is a component of the epsilon DNA polymerase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64F4. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10489 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035644
4234 CG10540 ;miro fruit fly Drosophila melanogaster The D. melanogaster gene CG10540 is reported here. It encodes a product with barbed-end actin capping activity involved in actin cytoskeleton organization and biogenesis which is a component of the F-actin capping protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 57B16. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10540 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034577
4235 CG10561 anon-37Cb;anon-37Cc;anon-37Cd;anon-37Cs;C2;CG6712;Cs;l(2)37Cs;l(2)37Cs: lethal(2)37Cs;lethal(2)37Cs;ORF1;ORF2;ORF3;transcription unit 37C2;transcription unit No. 2;TU37C1;TU37C2;TuC1 fruit fly Drosophila melanogaster The D. melanogaster gene CG10561 is reported here. It has also been known in FlyBase as anon-37Cb, anon-37Cc, anon-37Cs and l(2)37Cs. It encodes a product with putative oxidoreductase activity (EC:1.-.-.-) involved in biological_process unknown which is a component of the cytoplasm; it is expressed in the adult (adult abdomen, adult head, adult thorax, ovary and testis). It has been sequenced and its amino acid sequence contains an amine oxidase. It has been mapped by recombination to 2-53.9 and cytologically to 37C1. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. CG10561 is discussed in 21 references (excluding sequence accessions), dated between 1986 and 2003. These include at least 16 molecular studies. FB FBgn0002036
4252 CG10638 anon-EST:Posey139;anon-WO0172774.89;anon-WO02059370.24;BEST:GH08269;CG10686;CG32101;p67;p70;Trailer hitch;Trailer-hitch;tral fruit fly Drosophila melanogaster The D. melanogaster gene CG10638 is reported here. It encodes a product with aldehyde reductase activity (EC:1.1.1.21). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 69C3--4. There is one recorded allele, which is wild-type. CG10638 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2004. These include at least one molecular study. FB FBgn0036290
4256 CG10664 ;IV;IV: transcript group IV fruit fly Drosophila melanogaster The D. melanogaster gene CG10664 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 38A8. There is one recorded allele, which is wild-type. CG10664 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0032833
4257 CG10670 BcDNA:GM10765;DmGEN;Gen fruit fly Drosophila melanogaster The D. melanogaster gene CG10670 is reported here. It has also been known in FlyBase as BcDNA:GM10765. It encodes a product with flap endonuclease activity involved in base-excision repair which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a 5'3'-Exonuclease N- and I-domains, a xeroderma pigmentosum group G/yeast RAD superfamily and a helix-hairpin-helix motif class 2 (Pol1-type). It has been mapped cytologically to 64C7. There is one recorded allele, which is wild-type. CG10670 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027914
4260 CG10685 fruit fly Drosophila melanogaster The D. melanogaster gene CG10685 is reported here. It encodes a product with DNA-directed RNA polymerase activity (EC:2.7.7.6) involved in transcription from Pol I promoter which is a component of the DNA-directed RNA polymerase I complex. It has been sequenced and its amino acid sequence contains a RNA polymerases L/13 to 16 Kd subunits. It has been mapped cytologically to 37C1. There is one recorded allele, which is wild-type. CG10685 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0032762
4262 CG10689 fruit fly Drosophila melanogaster The D. melanogaster gene CG10689 is reported here. It encodes a product with RNA helicase activity (EC:2.7.7.-) involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 37C1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG10689 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032759
4264 CG10695 fruit fly Drosophila melanogaster The D. melanogaster gene CG10695 is reported here. It encodes a product with microtubule motor activity involved in microtubule-based movement which is a component of the kinesin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 6C1. There is one recorded allele, which is wild-type. CG10695 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029878
4270 CG10731 ;CG33038 fruit fly Drosophila melanogaster The D. melanogaster gene CG10731 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. There is one recorded allele, which is wild-type. CG10731 is discussed in 3 references (excluding sequence accessions), dated between 2001 and 2003. These include at least one molecular study. FB FBgn0034081
4272 CG10738 ;GYC fruit fly Drosophila melanogaster The D. melanogaster gene CG10738 is reported here. It encodes a product with guanylate cyclase activity (EC:4.6.1.2) putatively involved in signal transduction which is putatively a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a guanylate cyclase. It has been mapped cytologically to 70B1. There is one recorded allele, which is wild-type. CG10738 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0036368
4274 CG10748 fruit fly Drosophila melanogaster The D. melanogaster gene CG10748 is reported here. It encodes a product with L-malate dehydrogenase activity (EC:1.1.1.37) involved in tricarboxylic acid cycle which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a lactate/malate dehydrogenase and a malate dehydrogenase active site. It has been mapped cytologically to 69F2. There is one recorded allele, which is wild-type. CG10748 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036327
4275 CG10749 fruit fly Drosophila melanogaster The D. melanogaster gene CG10749 is reported here. It encodes a product with L-malate dehydrogenase activity (EC:1.1.1.37) involved in tricarboxylic acid cycle which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a lactate/malate dehydrogenase and a malate dehydrogenase active site. It has been mapped cytologically to 69F2. There is one recorded allele, which is wild-type. CG10749 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0036328
4277 CG10754 fruit fly Drosophila melanogaster The D. melanogaster gene CG10754 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a RNA-binding protein C2H2 Zn-finger domain, a zinc finger, C2H2 type and a U1-like zinc finger. It has been mapped cytologically to 69E4. There is one recorded allele, which is wild-type. CG10754 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036314
4278 CG1076 fruit fly Drosophila melanogaster The D. melanogaster gene CG1076 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) putatively involved in cation transport which is a component of the hydrogen-transporting ATPase V1 domain. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 83D4. There is one recorded allele, which is wild-type. CG1076 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037402
4286 CG10822 fruit fly Drosophila melanogaster The D. melanogaster gene CG10822 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is putatively a component of the dynein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 56F3. There is one recorded allele, which is wild-type. CG10822 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034478
4289 CG10834 fruit fly Drosophila melanogaster The D. melanogaster gene CG10834 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is putatively a component of the dynein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 40E3. There is one recorded allele, which is wild-type. CG10834 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0032972
4291 CG10839 BG:DS07486.2 fruit fly Drosophila melanogaster The D. melanogaster gene CG10839 is reported here. It has also been known in FlyBase as BG:DS07486.2. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 35E1. There is one recorded allele, which is wild-type. CG10839 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0028858
4292 CG10845 fruit fly Drosophila melanogaster The D. melanogaster gene CG10845 is reported here. It encodes a product with motor activity putatively involved in cytoskeleton organization and biogenesis which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 96B4--5. There is one recorded allele, which is wild-type. CG10845 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2002. These include at least one molecular study. FB FBgn0039246
4293 CG10859 fruit fly Drosophila melanogaster The D. melanogaster gene CG10859 is reported here. It encodes a product with motor activity putatively involved in microtubule-based movement which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 34B10. There is one recorded allele, which is wild-type. CG10859 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0032520
4305 CG10909 fruit fly Drosophila melanogaster The D. melanogaster gene CG10909 is reported here. It encodes a product with putative RNA binding involved in 35S primary transcript processing which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a fibrillarin. It has been mapped cytologically to 87D4. There is one recorded allele, which is wild-type. CG10909 is discussed in 2 references (excluding sequence accessions), both dating from 2003. FB FBgn0038090
4306 CG10920 fruit fly Drosophila melanogaster The D. melanogaster gene CG10920 is reported here. It encodes a product with carrier activity putatively involved in transport which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7C1. There is one recorded allele, which is wild-type. CG10920 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0029963
4307 CG10924 fruit fly Drosophila melanogaster The D. melanogaster gene CG10924 is reported here. It encodes a product with phosphoenolpyruvate carboxykinase (GTP) activity (EC:4.1.1.32) involved in gluconeogenesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a phosphoenolpyruvate carboxykinase (GTP). It has been mapped cytologically to 55D1--2. There is one recorded allele, which is wild-type. CG10924 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034356
4308 CG10932 fruit fly Drosophila melanogaster The D. melanogaster gene CG10932 is reported here. It encodes a product with acetyl-CoA C-acetyltransferase activity (EC:2.3.1.9) involved in pyruvate metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7C1. There is one recorded allele, which is wild-type. CG10932 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029969
4319 CG11015 anon-EST:Posey143;anon-WO0118547.187;BcDNA:RH49324;Vb fruit fly Drosophila melanogaster The D. melanogaster gene CG11015 is reported here. It has also been known in FlyBase as BcDNA:RH49324, anon-EST:Posey143 and anon-ESTPosey143. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome c oxidase, subunit Vb. It has been mapped cytologically to 26E3. There is one recorded allele, which is wild-type. CG11015 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031830
4327 CG11043 ;Vb fruit fly Drosophila melanogaster The D. melanogaster gene CG11043 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome c oxidase, subunit Vb. It has been mapped cytologically to 26E3. There is one recorded allele, which is wild-type. CG11043 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031831
4338 CG11092 BcDNA:LD21129 fruit fly Drosophila melanogaster The D. melanogaster gene CG11092 is reported here. It has also been known in FlyBase as BcDNA:LD21129. It encodes a product with putative transporter activity putatively involved in protein targeting which is a component of the nuclear pore. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 12C2. There is one recorded allele, which is wild-type. CG11092 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027537
4340 CG11107 anon-EST:Liang-1.18;clone 1.18 fruit fly Drosophila melanogaster The D. melanogaster gene CG11107 is reported here. It encodes a product with ATP dependent helicase activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 43B2. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG11107 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033160
4341 CG11109 ;CT31087 fruit fly Drosophila melanogaster The D. melanogaster gene CG11109 is reported here. It encodes a product with rRNA methyltransferase activity (EC:2.1.1.-) putatively involved in rRNA metabolism which is a component of the nucleolus. It has been sequenced and its amino acid sequence contains a SAM (and some other nucleotide) binding motif and a PUA domain. It has been mapped cytologically to 80B2. There is one recorded allele, which is wild-type. CG11109 is discussed in 8 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0037200
4342 CG11110 fruit fly Drosophila melanogaster The D. melanogaster gene CG11110 is reported here. It encodes a product with peptidase activity (EC:3.4.-.-) involved in mitochondrial processing which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a bacterial leader peptidase 1 (S26A) family and a signal peptidase. It has been mapped cytologically to 57A8. There is one recorded allele, which is wild-type. CG11110 is discussed in 4 references (excluding sequence accessions), all dating from 2003. FB FBgn0034535
4350 CG11152 ;Dmcg11152 fruit fly Drosophila melanogaster The D. melanogaster gene CG11152 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a fork head domain. It has been mapped cytologically to 102C4. There is one recorded allele, which is wild-type. CG11152 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0039937
4356 CG11190 ;Dm*AAF46367/27-522 fruit fly Drosophila melanogaster The D. melanogaster gene CG11190 is reported here. It encodes a product involved in attachment of GPI anchor to protein which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7E6. There are 7 recorded alleles: 6 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. CG11190 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0030035
4358 CG11196 fruit fly Drosophila melanogaster The D. melanogaster gene CG11196 is reported here. It encodes a product with dicarboxylic acid transporter activity putatively involved in cation transport which is a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial carrier domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 44A2. There is one recorded allele, which is wild-type. CG11196 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0033248
4367 CG11242 fruit fly Drosophila melanogaster The D. melanogaster gene CG11242 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in cytoskeleton organization and biogenesis which is a component of the cytoskeleton. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 56D11--12. There is one recorded allele, which is wild-type. CG11242 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034451
4369 CG11261 ;CUL6 fruit fly Drosophila melanogaster The D. melanogaster gene CG11261 is reported here. It encodes a product putatively involved in induction of apoptosis which is a component of the nuclear ubiquitin ligase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 69F5. There is one recorded allele, which is wild-type. CG11261 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036332
4371 CG11266 CAPER;CC1.3;HCC1 fruit fly Drosophila melanogaster The D. melanogaster gene CG11266 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in RNA splicing which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif) and a cheW-like domain. It has been mapped cytologically to 27D5. There is one recorded allele, which is wild-type. CG11266 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031883
4372 CG11267 anon-WO0118547.175 fruit fly Drosophila melanogaster The D. melanogaster gene CG11267 is reported here. It encodes a product with chaperone activity involved in 'de novo' protein folding which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 69F5. There is one recorded allele, which is wild-type. CG11267 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036334
4378 CG11294 ;CT31519 fruit fly Drosophila melanogaster The D. melanogaster gene CG11294 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 8A2. There is one recorded allele, which is wild-type. CG11294 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0030058
4379 CG11299 BcDNA:GH20113;BEST:GH20113 fruit fly Drosophila melanogaster The D. melanogaster gene CG11299 is reported here. It has also been known in FlyBase as BEST:GH20113 and BcDNA:GH20113. It encodes a product putatively involved in regulation of cell cycle which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 59F6--7. There is one recorded allele, which is wild-type. CG11299 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0034897
4385 CG11320 ;CT31597 fruit fly Drosophila melanogaster The D. melanogaster gene CG11320 is reported here. It encodes a product involved in cell adhesion which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an immunoglobulin and major histocompatibility complex domain, an immunoglobulin C-2 type and an immunoglobulin-like. It has been mapped cytologically to 26F1. There is one recorded allele, which is wild-type. CG11320 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031837
4390 CG11340 fruit fly Drosophila melanogaster The D. melanogaster gene CG11340 is reported here. It encodes a product with glycine-gated chloride channel activity putatively involved in anion transport which is a component of the glycine-gated chloride channel complex. It has been sequenced and its amino acid sequence contains a gamma-aminobutyric acid A (GABAA) receptor and a neurotransmitter-gated ion-channel. It has been mapped cytologically to 100C1. There is one recorded allele, which is wild-type. CG11340 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0039840
4391 CG1135 ;p78 fruit fly Drosophila melanogaster The D. melanogaster gene CG1135 is reported here. It encodes a product which is a component of the nucleolus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64A4. There is one recorded allele, which is wild-type. CG1135 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035489
4397 CG11386 ;CG33222 fruit fly Drosophila melanogaster The D. melanogaster gene CG11386 is reported here. It encodes a product with putative nucleic acid binding putatively involved in regulation of translation which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein S6e. It has been mapped cytologically to 7C2. There is one recorded allele, which is wild-type. CG11386 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2004. FB FBgn0029973
4400 CG1140 3-oxoacid CoA-transferase;3-oxoacid-CoA-transferase;BcDNA:RH54340;cDNA B;citric acid synthetase;CT1116 fruit fly Drosophila melanogaster The D. melanogaster gene CG1140 is reported here. It has also been known in FlyBase as BcDNA:RH54340. It encodes a product with 3-oxoacid CoA-transferase activity (EC:2.8.3.5) involved in ketone body catabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a coenzyme A transferase. It has been mapped cytologically to 62B12. There is one recorded allele, which is wild-type. CG1140 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035298
4406 CG11419 fruit fly Drosophila melanogaster The D. melanogaster gene CG11419 is reported here. It encodes a product with putative ligase activity (EC:6.-.-.-) involved in mitotic anaphase which is a component of the anaphase-promoting complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 54C1. There is one recorded allele, which is wild-type. CG11419 is discussed in 7 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0034231
4407 CG11423 fruit fly Drosophila melanogaster The D. melanogaster gene CG11423 is reported here. It encodes a product with NADH dehydrogenase (ubiquinone) activity (EC:1.6.5.3) putatively involved in electron transport which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence contains a respiratory-chain NADH dehydrogenase 51 Kd subunit. It has been mapped cytologically to 54C12. There is one recorded allele, which is wild-type. CG11423 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0034251
4416 CG11455 fruit fly Drosophila melanogaster The D. melanogaster gene CG11455 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 21B1--2. There is one recorded allele, which is wild-type. CG11455 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031228
4421 CG11500 ;CG31042 fruit fly Drosophila melanogaster The D. melanogaster gene CG11500 is reported here. It encodes a product with signal peptidase activity involved in signal peptide processing which is a component of the signal peptidase complex. It has been sequenced and its amino acid sequence is also available. There is one recorded allele, which is wild-type. CG11500 is discussed in 2 references (excluding sequence accessions), dated between 2000 and 2002. These include at least one molecular study. FB FBgn0040623
4422 CG11508 fruit fly Drosophila melanogaster The D. melanogaster gene CG11508 is reported here. It encodes a product which is a component of the snRNA-activating protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 44B4. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG11508 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0033267
4425 RpL6 CG11522 fruit fly Drosophila melanogaster The D. melanogaster gene RpL6 is reported here. It has also been known in FlyBase as CG11522. It encodes a product with putative nucleic acid binding putatively involved in protein biosynthesis which is a component of the large ribosomal subunit. It has been sequenced and its amino acid sequence contains a ribosomal protein L6E. It has been mapped cytologically to 100C7. There is one recorded allele, which is wild-type. RpL6 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039857
4431 CG11552 fruit fly Drosophila melanogaster The D. melanogaster gene CG11552 is reported here. It encodes a product involved in proteolysis and peptidolysis which is a component of the proteasome regulatory particle (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. There is one recorded allele, which is wild-type. CG11552 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2004. These include at least one molecular study. FB FBgn0036465
4437 CG11617 fruit fly Drosophila melanogaster The D. melanogaster gene CG11617 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 21B4. There is one recorded allele, which is wild-type. CG11617 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031232
4441 CG11641 BcDNA:AT16994 fruit fly Drosophila melanogaster The D. melanogaster gene CG11641 is reported here. It has also been known in FlyBase as BcDNA:AT16994. It encodes a product with transcription factor activity putatively involved in cell homeostasis which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a 'POU' domain and a homeobox domain. It has been mapped cytologically to 44C4. There is one recorded allele, which is wild-type. CG11641 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033288
4442 CG11642 BACR7A4.5;CG16994;CG18830;CG32815;EG:BACR7A4.5 fruit fly Drosophila melanogaster The D. melanogaster gene CG11642 is reported here. It has also been known in FlyBase as CG18830 and EG:BACR7A4.5. It encodes a product involved in SRP-dependent cotranslational membrane targeting which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 1D2. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG11642 is discussed in 10 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 3 molecular studies. FB FBgn0040340
4446 CG11661 CG11661 fruit fly Drosophila melanogaster FB FBgn0036682
4453 CG11674 fruit fly Drosophila melanogaster The D. melanogaster gene CG11674 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 12E5. There is one recorded allele, which is wild-type. CG11674 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030551
4454 CG11703 anon-WO0140519.49;JYbeta2 fruit fly Drosophila melanogaster The D. melanogaster gene CG11703 is reported here. It encodes a product with sodium/potassium-exchanging ATPase activity (EC:3.6.3.9) which is a component of the sodium/potassium-exchanging ATPase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 91F12. There is one recorded allele, which is wild-type. CG11703 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2002. These include at least one molecular study. FB FBgn0038690
4460 translin CG11761 fruit fly Drosophila melanogaster The D. melanogaster gene translin is reported here. It has also been known in FlyBase as CG11761. It encodes a product with DNA binding putatively involved in DNA recombination. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 47A11. There is one recorded allele, which is wild-type. translin is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033528
4461 CG11763 fruit fly Drosophila melanogaster The D. melanogaster gene CG11763 is reported here. It encodes a product with RAN protein binding putatively involved in protein targeting which is a component of the centrosome. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 47A7. There is one recorded allele, which is wild-type. CG11763 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033522
4466 CG11779 BcDNA:GM03811;BEST:GM03811 fruit fly Drosophila melanogaster The D. melanogaster gene CG11779 is reported here. It has also been known in FlyBase as BEST:GM03811 and BcDNA:GM03811. It encodes a product with protein translocase activity involved in protein-mitochondrial targeting which is a component of the mitochondrial inner membrane presequence translocase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 91F6--7. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. CG11779 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0038683
4470 CG11799 ;DmLD16137 fruit fly Drosophila melanogaster The D. melanogaster gene CG11799 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a fork head domain. It has been mapped cytologically to 68A7. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. CG11799 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0036134
4475 CG11835 fruit fly Drosophila melanogaster The D. melanogaster gene CG11835 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter. It has been sequenced and its amino acid sequence contains a molluscan rhodopsin C-terminal tail. It has been mapped cytologically to 21E1. There is one recorded allele, which is wild-type. CG11835 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031264
4494 CG11909 ;CT33098 fruit fly Drosophila melanogaster The D. melanogaster gene CG11909 is reported here. It encodes a product with alpha-glucosidase activity (EC:3.2.1.20) putatively involved in monosaccharide metabolism which is a component of the alpha-glucosidase complex. It has been sequenced and its amino acid sequence contains a glycosyl hydrolases family 31. It has been mapped cytologically to 96D2. There is one recorded allele, which is wild-type. CG11909 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039330
4498 CG11913 CG111913 fruit fly Drosophila melanogaster The D. melanogaster gene CG11913 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence contains a NADH-ubiquinone oxidoreductase 49Kd chain. It has been mapped cytologically to 96D2. There is one recorded allele, which is wild-type. CG11913 is discussed in 4 references (excluding sequence accessions), all dating from 2003. FB FBgn0039331
4500 CG11920 fruit fly Drosophila melanogaster The D. melanogaster gene CG11920 is reported here. It encodes a product with putative RNA binding putatively involved in rRNA metabolism which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 96B20. There is one recorded allele, which is wild-type. CG11920 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039274
4501 CG1193 ;DmCG1193 fruit fly Drosophila melanogaster The D. melanogaster gene CG1193 is reported here. It encodes a product with microtubule severing activity putatively involved in microtubule-based process which is a component of the katanin. It has been sequenced and its amino acid sequence contains a AAA ATPase superfamily. It has been mapped cytologically to 83C3--4. There is one recorded allele, which is wild-type. CG1193 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0037375
4506 CG11970 BcDNA:LD23876 fruit fly Drosophila melanogaster The D. melanogaster gene CG11970 is reported here. It has also been known in FlyBase as BcDNA:LD23876. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 85C1. There are 4 recorded alleles: 3 classical mutants (none available from the public stock centers) and 1 wild-type. CG11970 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027503
4510 CG12000 &bgr;-type 4 subunit;anon-WO0118547.326;GC12000 fruit fly Drosophila melanogaster The D. melanogaster gene CG12000 is reported here. It encodes a product with endopeptidase activity involved in ubiquitin-dependent protein catabolism which is a component of the cytoplasm. It has been sequenced and its amino acid sequence contains a proteasome B-type subunit and a multispecific proteases of the proteasome. It has been mapped cytologically to 82F11. There is one recorded allele, which is wild-type. CG12000 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037314
4512 CG12010 fruit fly Drosophila melanogaster The D. melanogaster gene CG12010 is reported here. It encodes a product with ATPase activity putatively involved in mitosis which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence contains a AAA ATPase superfamily. It has been mapped cytologically to 63D2. There is one recorded allele, which is wild-type. CG12010 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035443
4513 PHGPx CG12013;DmPHGPx fruit fly Drosophila melanogaster The D. melanogaster gene PHGPx is reported here. It has also been known in FlyBase as CG12013. It encodes a product with glutathione peroxidase activity (EC:1.11.1.9) involved in response to lipid hydroperoxide which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a glutathione peroxidase. It has been mapped cytologically to 63D1. There is one recorded allele, which is wild-type. PHGPx is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0035438
4515 CG12018 BcDNA:HL03874 fruit fly Drosophila melanogaster The D. melanogaster gene CG12018 is reported here. It has also been known in FlyBase as BcDNA:HL03874. It encodes a product with delta DNA polymerase activity involved in DNA replication which is a component of the delta DNA polymerase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 62B4. There is one recorded allele, which is wild-type. CG12018 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027903
4517 CG12027 fruit fly Drosophila melanogaster The D. melanogaster gene CG12027 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) which is a component of the proton-transporting ATP synthase complex (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64C4. There is one recorded allele, which is wild-type. CG12027 is discussed in 2 references (excluding sequence accessions), both dating from 1999. FB FBgn0035585
4521 CG12042 ;P62 DYNACTIN fruit fly Drosophila melanogaster The D. melanogaster gene CG12042 is reported here. It encodes a product with putative actin binding putatively involved in microtubule-based movement which is putatively a component of the dynactin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 43E9. There is one recorded allele, which is wild-type. CG12042 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033206
4525 CG12079 fruit fly Drosophila melanogaster The D. melanogaster gene CG12079 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence contains a respiratory-chain NADH dehydrogenase 30 Kd subunit. It has been mapped cytologically to 63B7. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. CG12079 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035404
4536 CG12140 fruit fly Drosophila melanogaster The D. melanogaster gene CG12140 is reported here. It encodes a product with electron-transferring-flavoprotein dehydrogenase activity (EC:1.5.5.1) involved in oxidative phosphorylation which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46C4. There is one recorded allele, which is wild-type. CG12140 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033465
4538 CG12151 fruit fly Drosophila melanogaster The D. melanogaster gene CG12151 is reported here. It encodes a product with protein serine/threonine phosphatase activity involved in protein amino acid dephosphorylation which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a serine/threonine phosphatases 2C catalytic domain. It has been mapped cytologically to 7B7. There is one recorded allele, which is wild-type. CG12151 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029958
4540 CG12161 fruit fly Drosophila melanogaster The D. melanogaster gene CG12161 is reported here. It encodes a product with endopeptidase activity putatively involved in proteolysis and peptidolysis which is a component of the proteasome core complex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a multispecific proteases of the proteasome. It has been mapped cytologically to 82F6. There is one recorded allele, which is wild-type. CG12161 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0037296
4545 CG12201 fruit fly Drosophila melanogaster The D. melanogaster gene CG12201 is reported here. It encodes a product with carnitine transporter activity putatively involved in lipid metabolism which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein) and a mitochondrial carrier domain. It has been mapped cytologically to 87A4. There is one recorded allele, which is wild-type. CG12201 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037970
4547 CG12203 fruit fly Drosophila melanogaster The D. melanogaster gene CG12203 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18C7. There is one recorded allele, which is wild-type. CG12203 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0031021
4549 CG12227 ;skpF fruit fly Drosophila melanogaster The D. melanogaster gene CG12227 is reported here. It encodes a product with ubiquitin-protein ligase activity (EC:6.3.2.19) putatively involved in chromosome segregation which is a component of the nuclear ubiquitin ligase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 59E1. There is one recorded allele, which is wild-type. CG12227 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0034863
4550 CG12233 ;FBgn0031024;l(1)G0156 CG12233 fruit fly Drosophila melanogaster FB FBgn0031024
4554 CG12262 fruit fly Drosophila melanogaster The D. melanogaster gene CG12262 is reported here. It encodes a product with acyl-CoA dehydrogenase activity (EC:1.3.99.3) involved in fatty acid beta-oxidation which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains an acyl-CoA dehydrogenase. It has been mapped cytologically to 66A10. There is one recorded allele, which is wild-type. CG12262 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035811
4555 CG12264 fruit fly Drosophila melanogaster The D. melanogaster gene CG12264 is reported here. It encodes a product with cysteine desulfhydrase activity (EC:4.4.1.-) involved in iron-sulfur cluster assembly which is a component of the cytoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 33B5. There is one recorded allele, which is wild-type. CG12264 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032393
4557 CG12267 fruit fly Drosophila melanogaster The D. melanogaster gene CG12267 is reported here. It encodes a product with DNA-directed RNA polymerase activity (EC:2.7.7.6) involved in transcription from Pol III promoter which is a component of the DNA-directed RNA polymerase III complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 87B11. There is one recorded allele, which is wild-type. CG12267 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038057
4559 RpS10a BcDNA:LD32148;CG12275;RpS10;S10 fruit fly Drosophila melanogaster The D. melanogaster gene RpS10a is reported here. It has also been known in FlyBase as BcDNA:LD32148 and CG12275. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98A14. There is one recorded allele, which is wild-type. RpS10a is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027494
4564 CG12295 &agr;2&dgr;;alpha[[2]]delta fruit fly Drosophila melanogaster The D. melanogaster gene CG12295 is reported here. It encodes a product with voltage-gated calcium channel activity putatively involved in cation transport which is a component of the voltage-gated calcium channel complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 50C5--6. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG12295 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033870
4568 RpS15Ab CG12324;CT22283 fruit fly Drosophila melanogaster The D. melanogaster gene RpS15Ab is reported here. It has also been known in FlyBase as CG12324. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein S8. It has been mapped cytologically to 47C1. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. RpS15Ab is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one study of natural polymorphisms and one molecular study. FB FBgn0033555
4571 CG12344 fruit fly Drosophila melanogaster The D. melanogaster gene CG12344 is reported here. It encodes a product with glycine-gated chloride channel activity putatively involved in anion transport which is a component of the glycine-gated chloride channel complex. It has been sequenced and its amino acid sequence contains a gamma-aminobutyric acid A (GABAA) receptor and a neurotransmitter-gated ion-channel. It has been mapped cytologically to 47C1--2. There is one recorded allele, which is wild-type. CG12344 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033558
4573 CG12361 fruit fly Drosophila melanogaster The D. melanogaster gene CG12361 is reported here. It encodes a product with transcription factor activity putatively involved in ectoderm development which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors and a homeobox domain. It has been mapped cytologically to 62B10--11. There is one recorded allele, which is wild-type. CG12361 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035292
4578 CG12400 BcDNA:RE29623 fruit fly Drosophila melanogaster The D. melanogaster gene CG12400 is reported here. It has also been known in FlyBase as BcDNA:RE29623. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 23D3. There is one recorded allele, which is wild-type. CG12400 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0031505
4579 CG12404 fruit fly Drosophila melanogaster The D. melanogaster gene CG12404 is reported here. It encodes a product with putative oxidoreductase activity (EC:1.-.-.-) which is a component of the Golgi membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 34A4. There is one recorded allele, which is wild-type. CG12404 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0032465
4580 CG12413 fruit fly Drosophila melanogaster The D. melanogaster gene CG12413 is reported here. It encodes a product with translation initiation factor activity involved in translational initiation which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an initiation factor 2 and a GTP-binding elongation factor. It has been mapped cytologically to 98D4. There is one recorded allele, which is wild-type. CG12413 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039588
4583 CG12460 ;CG40051 fruit fly Drosophila melanogaster The D. melanogaster gene CG12460 is reported here. It has also been known in FlyBase as CG40051. It encodes a product with pre-mRNA splicing factor activity involved in RNA splicing which is a component of the spliceosome complex. It has been sequenced. There is one recorded allele, which is wild-type. CG12460 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0040045
4586 CG1249 BcDNA:LD03002 fruit fly Drosophila melanogaster The D. melanogaster gene CG1249 is reported here. It has also been known in FlyBase as BcDNA:LD03002. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a small nuclear ribonucleoprotein (Sm protein). It has been mapped cytologically to 83E4. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG1249 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0037434
4590 CG12534 fruit fly Drosophila melanogaster The D. melanogaster gene CG12534 is reported here. It encodes a product with flavin-linked sulfhydryl oxidase activity putatively involved in electron transport which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18F1. There is one recorded allele, which is wild-type. CG12534 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031068
4595 CG12602 fruit fly Drosophila melanogaster The D. melanogaster gene CG12602 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) putatively involved in cation transport which is a component of the hydrogen-transporting ATPase V0 domain. It has been sequenced and its amino acid sequence contains a V-type ATPase 116kDa subunit family. It has been mapped cytologically to 33A1. There is one recorded allele, which is wild-type. CG12602 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032373
4596 CG12648 ;CG33557 fruit fly Drosophila melanogaster The D. melanogaster gene CG12648 is reported here. It encodes a product with transcription factor activity involved in regulation of transcription which is a component of the nucleus. It has been sequenced. There is one recorded allele, which is wild-type. CG12648 is discussed in 4 references (excluding sequence accessions), dated between 2001 and 2003. FB FBgn0040938
4598 CG1268 fruit fly Drosophila melanogaster The D. melanogaster gene CG1268 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) putatively involved in cation transport which is a component of the hydrogen-translocating V-type ATPase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64A12. There is one recorded allele, which is wild-type. CG1268 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035521
4599 CG12703 ;i17 fruit fly Drosophila melanogaster The D. melanogaster gene CG12703 is reported here. It encodes a product with ATP-binding cassette (ABC) transporter activity (EC:3.6.3.-) involved in peroxisome organization and biogenesis which is a component of the integral to peroxisomal membrane. It has been sequenced and its amino acid sequence contains a ABC transporter. It has been mapped cytologically to 18F1. There is one recorded allele, which is wild-type. CG12703 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031069
4601 CG12736 fruit fly Drosophila melanogaster The D. melanogaster gene CG12736 is reported here. It encodes a product with translation elongation factor activity involved in translational elongation which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a GTP-binding elongation factor. It has been mapped cytologically to 43D1. There is one recorded allele, which is wild-type. CG12736 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0033184
4602 RpL28 anon-WO0118547.321;BcDNA:GH04183;CG12740;L28 fruit fly Drosophila melanogaster The D. melanogaster gene RpL28 is reported here. It has also been known in FlyBase as CG12740. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal L28e protein family. It has been mapped cytologically to 63B14. There is one recorded allele, which is wild-type. RpL28 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035422
4607 RpL21 anon-EST:Posey18;anon-EST:Posey30;BcDNA:RH06526;CG12775 fruit fly Drosophila melanogaster The D. melanogaster gene RpL21 is reported here. It has also been known in FlyBase as BcDNA:RH06526, CG12775 and anon-EST:Posey18. It encodes a product with putative structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein L21E. It has been mapped cytologically to 40F6. There is one recorded allele, which is wild-type. RpL21 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032987
4609 CG12782 fruit fly Drosophila melanogaster The D. melanogaster gene CG12782 is reported here. It encodes a product with putative RNA binding involved in poly(A)+ mRNA-nucleus export which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 59D4. There is one recorded allele, which is wild-type. CG12782 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034838
4610 CG12789 BEST:CK01577;CK01577 fruit fly Drosophila melanogaster The D. melanogaster gene CG12789 is reported here. It has also been known in FlyBase as BEST:CK01577. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a CD36 family. It has been mapped cytologically to 27F6. There is one recorded allele, which is wild-type. CG12789 is discussed in 10 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 2 molecular studies. FB FBgn0025697
4614 CG12810 ;CG31477 fruit fly Drosophila melanogaster The D. melanogaster gene CG12810 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukarya). It has been sequenced. There is one recorded allele, which is wild-type. CG12810 is discussed in 3 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0040541
4615 CG12859 anon-EST:fe3B12;anon-fast-evolving-3B12 fruit fly Drosophila melanogaster The D. melanogaster gene CG12859 is reported here. It has also been known in FlyBase as anon-EST:fe3B12 and anon-fe3B12. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 51C2. There is one recorded allele, which is wild-type. CG12859 is discussed in 5 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one molecular study. FB FBgn0033961
4621 CG12909 fruit fly Drosophila melanogaster The D. melanogaster gene CG12909 is reported here. It encodes a product with RNA binding which is a component of the nucleolus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 47A1. There is one recorded allele, which is wild-type. CG12909 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033507
4624 CG12918 fruit fly Drosophila melanogaster The D. melanogaster gene CG12918 is reported here. It encodes a product which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46D9. There is one recorded allele, which is wild-type. CG12918 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0033477
4627 CG12954 BcDNA:RE19416;YmL27 fruit fly Drosophila melanogaster The D. melanogaster gene CG12954 is reported here. It has also been known in FlyBase as BcDNA:RE19416. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the mitochondrial large ribosomal subunit. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 51E7. There is one recorded allele, which is wild-type. CG12954 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0034001
4630 CG13030 anon-WO0140519.228 fruit fly Drosophila melanogaster The D. melanogaster gene CG13030 is reported here. It encodes a product which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 73D3. There is one recorded allele, which is wild-type. CG13030 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0036669
4639 CG13167 fruit fly Drosophila melanogaster The D. melanogaster gene CG13167 is reported here. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the hydrogen-transporting ATPase V1 domain. It has been sequenced and its amino acid sequence contains a ATP synthase subunit D. It has been mapped cytologically to 48F1. There is one recorded allele, which is wild-type. CG13167 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0033706
4640 CG1319 BcDNA:RE08888;BcDNA:RH09920 fruit fly Drosophila melanogaster The D. melanogaster gene CG1319 is reported here. It has also been known in FlyBase as BcDNA:RE08888 and BcDNA:RH09920. It encodes a product with electron carrier activity putatively involved in ferredoxin metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a ferredoxin and an adrenodoxin. It has been mapped cytologically to 64B1. There is one recorded allele, which is wild-type. CG1319 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0035529
4647 CG13277 BcDNA:RH73529 fruit fly Drosophila melanogaster The D. melanogaster gene CG13277 is reported here. It has also been known in FlyBase as BcDNA:RH73529. It encodes a product with putative pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U6. It has been sequenced and its amino acid sequence contains a small nuclear ribonucleoprotein (Sm protein). It has been mapped cytologically to 36A14. There is one recorded allele, which is wild-type. CG13277 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032599
4663 CG13393 BcDNA:RE23864 fruit fly Drosophila melanogaster The D. melanogaster gene CG13393 is reported here. It has also been known in FlyBase as BcDNA:RE23864. It encodes a product with oligosaccharyl transferase activity (EC:2.4.1.-) involved in negative regulation of apoptosis which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 29B4. There is one recorded allele, which is wild-type. CG13393 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032035
4669 CG13424 fruit fly Drosophila melanogaster The D. melanogaster gene CG13424 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lamda; and other repressors and a homeobox domain. It has been mapped cytologically to 57A5. There is one recorded allele, which is wild-type. CG13424 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2000. These include at least one molecular study. FB FBgn0034520
4670 CG13426 fruit fly Drosophila melanogaster The D. melanogaster gene CG13426 is reported here. It encodes a product with protein transporter activity involved in SRP-dependent cotranslational membrane targeting, translocation which is a component of the translocon. It has been sequenced and its amino acid sequence contains a protein secE/sec61-γ domain. It has been mapped cytologically to 57A4. There is one recorded allele, which is wild-type. CG13426 is discussed in 2 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034510
4696 CG1379 fruit fly Drosophila melanogaster The D. melanogaster gene CG1379 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains an acute myeloid leukemia 1 protein (AML 1)/Runt. It has been mapped cytologically to 19D3--E1. There is one recorded allele, which is wild-type. CG1379 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031124
4703 CG13900 fruit fly Drosophila melanogaster The D. melanogaster gene CG13900 is reported here. It encodes a product with damaged DNA binding involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 61D2. There is one recorded allele, which is wild-type. CG13900 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035162
4705 CG13916 anon-WO0109301.35;CG1;Complementation group 1;pairing failure-1;pf-1;SA-2;sd-1;SNM fruit fly Drosophila melanogaster The D. melanogaster gene CG13916 is reported here. It encodes a product with putative chromatin binding putatively involved in ectoderm development which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 62A3. There is one recorded allele, which is wild-type. CG13916 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035220
4706 CG13930 fruit fly Drosophila melanogaster The D. melanogaster gene CG13930 is reported here. It encodes a product with motor activity putatively involved in microtubule-based movement which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 62A12. There is one recorded allele, which is wild-type. CG13930 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035256
4721 CG14060 fruit fly Drosophila melanogaster The D. melanogaster gene CG14060 is reported here. It encodes a product putatively involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U2. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 73E1. There is one recorded allele, which is wild-type. CG14060 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0036683
4723 CG14077 ;VIa fruit fly Drosophila melanogaster The D. melanogaster gene CG14077 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome c oxidase, subunit VIa. It has been mapped cytologically to 75E5. There is one recorded allele, which is wild-type. CG14077 is discussed in 2 references (excluding sequence accessions), dated between 1999 and 2001. FB FBgn0036830
4728 CG1420 fruit fly Drosophila melanogaster The D. melanogaster gene CG1420 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a zn-finger CCHC type. It has been mapped cytologically to 98F5--6. There is one recorded allele, which is wild-type. CG1420 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039626
4729 RpS10b CG14206;CT33819;GM19176;i3;i73 fruit fly Drosophila melanogaster The D. melanogaster gene RpS10b is reported here. It has also been known in FlyBase as CG14206. It encodes a product with structural constituent of ribosome putatively involved in cytoskeleton organization and biogenesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18D3. There are 2 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 1 wild-type. RpS10b is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031035
4731 CG14214 fruit fly Drosophila melanogaster The D. melanogaster gene CG14214 is reported here. It encodes a product with protein transporter activity involved in protein transport which is a component of the integral to endoplasmic reticulum membrane. It has been sequenced and its amino acid sequence contains a protein secE/sec61-γ domain. It has been mapped cytologically to 18D11--12. There is one recorded allele, which is wild-type. CG14214 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031049
4738 CG14235 ;Cytochrome c oxidase subunitVIb fruit fly Drosophila melanogaster The D. melanogaster gene CG14235 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) putatively involved in electron transport which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18E5. There is one recorded allele, which is wild-type. CG14235 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031066
4751 CG14476 BcDNA:GH04962;clot#312;glucosidase II fruit fly Drosophila melanogaster The D. melanogaster gene CG14476 is reported here. It has also been known in FlyBase as BcDNA:GH04962. It encodes a product with alpha-glucosidase activity (EC:3.2.1.20) putatively involved in polysaccharide metabolism which is a component of the alpha-glucosidase complex. It has been sequenced and its amino acid sequence contains a glycosyl hydrolases family 31. It has been mapped cytologically to 20A4. There is one recorded allele, which is wild-type. CG14476 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0027588
4752 CG14482 fruit fly Drosophila melanogaster The D. melanogaster gene CG14482 is reported here. It encodes a product with ubiquinol-cytochrome-c reductase activity (EC:1.10.2.2) involved in mitochondrial electron transport, ubiquinol to cytochrome c which is a component of the ubiquinol-cytochrome-c reductase complex (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 54C9. There is one recorded allele, which is wild-type. CG14482 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0034245
4755 CG14508 fruit fly Drosophila melanogaster The D. melanogaster gene CG14508 is reported here. It encodes a product with electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity involved in mitochondrial electron transport, ubiquinol to cytochrome c which is a component of the ubiquinol-cytochrome-c reductase complex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome c family heme-binding site and a cytochrome c1. It has been mapped cytologically to 99A1. There is one recorded allele, which is wild-type. CG14508 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039651
4772 CG14641 fruit fly Drosophila melanogaster The D. melanogaster gene CG14641 is reported here. It encodes a product with putative RNA binding. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif) and a zinc finger C-x8-C-x5-C-x3-H type. It has been mapped cytologically to 82A1. There is one recorded allele, which is wild-type. CG14641 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037220
4776 CG14690 ;dtomboy20;tomboy20 fruit fly Drosophila melanogaster The D. melanogaster gene CG14690 is reported here. It encodes a product with protein translocase activity involved in protein-mitochondrial targeting which is a component of the mitochondrial outer membrane translocase complex. It has been sequenced and its amino acid sequence contains a MAS20 protein import receptor signature. It has been mapped cytologically to 86C5. There is one recorded allele, which is wild-type. CG14690 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037828
4790 CG14740 anon-WO0140519.178 fruit fly Drosophila melanogaster The D. melanogaster gene CG14740 is reported here. It encodes a product with citrate (Si)-synthase activity (EC:2.3.3.1) involved in tricarboxylic acid cycle which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a citrate synthase. It has been mapped cytologically to 87A6. There is one recorded allele, which is wild-type. CG14740 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0037988
4793 RpL13A anon-EST:fe1A5;anon-EST:Posey125;anon-fast-evolving-1A5;bs25f04.y1;CG1475;L13a2 fruit fly Drosophila melanogaster The D. melanogaster gene RpL13A is reported here. It has also been known in FlyBase as CG1475, anon-EST:Posey125, anon-EST:fe1A5 and anon-fe1A5. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein L13. It has been mapped cytologically to 83B6--7. There is one recorded allele, which is wild-type. RpL13A is discussed in 12 references (excluding sequence accessions), dated between 1997 and 2003. These include at least 2 molecular studies. FB FBgn0037351
4795 CG14763 fruit fly Drosophila melanogaster The D. melanogaster gene CG14763 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is putatively a component of the dynein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 43F9. There is one recorded allele, which is wild-type. CG14763 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2000. These include at least one molecular study. FB FBgn0033243
4796 CG14767 ;CG8575 fruit fly Drosophila melanogaster The D. melanogaster gene CG14767 is reported here. It has also been known in FlyBase as CG8575. It encodes a product with nucleobase transporter activity which is a component of the Golgi membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 44E2--3. There is one recorded allele, which is wild-type. CG14767 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0040777
4797 CG14778 fruit fly Drosophila melanogaster The D. melanogaster gene CG14778 is reported here. It encodes a product with putative receptor signaling protein activity which is a component of the integral to peroxisomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2A4. There is one recorded allele, which is wild-type. CG14778 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0029580
4801 CG14802 ;dp28b;EG:63B12.13;p28;Srb5/Med28b fruit fly Drosophila melanogaster The D. melanogaster gene CG14802 is reported here. It has also been known in FlyBase as EG:63B12.13. It encodes a product with RNA polymerase II transcription mediator activity which is a component of the mediator complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2B13. There is one recorded allele, which is wild-type. CG14802 is discussed in 8 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0026873
4805 CG14838 fruit fly Drosophila melanogaster The D. melanogaster gene CG14838 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is putatively a component of the dynein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 66A6. There is one recorded allele, which is wild-type. CG14838 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2000. These include at least one molecular study. FB FBgn0035799
4828 CG15011 fruit fly Drosophila melanogaster The D. melanogaster gene CG15011 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger NF-X1 type. It has been mapped cytologically to 64A12. There is one recorded allele, which is wild-type. CG15011 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035518
4835 CG15093 ;CT34968 fruit fly Drosophila melanogaster The D. melanogaster gene CG15093 is reported here. It encodes a product with 3-hydroxyisobutyrate dehydrogenase activity (EC:1.1.1.31) involved in amino acid metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a 6-phosphogluconate dehydrogenase. It has been mapped cytologically to 55F2. There is one recorded allele, which is wild-type. CG15093 is discussed in 13 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0034390
4845 CG1516 BcDNA;BcDNA:GH06348;GH06348 fruit fly Drosophila melanogaster The D. melanogaster gene CG1516 is reported here. It has also been known in FlyBase as BcDNA:GH06348. It encodes a product with pyruvate carboxylase activity (EC:6.4.1.1) involved in pyruvate metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a HMG-CoA Lyase-like family, a carbamoyl-phosphate synthase and a biotin-requiring enzymes attachment site. It has been mapped cytologically to 46B10--12. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG1516 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027580
4847 CG15220 BcDNA:RH55360 fruit fly Drosophila melanogaster The D. melanogaster gene CG15220 is reported here. It has also been known in FlyBase as BcDNA:RH55360. It encodes a product with putative DNA binding putatively involved in DNA replication which is a component of the DNA replication factor A complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 10D1. There is one recorded allele, which is wild-type. CG15220 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030322
4862 CG15388 agrin-like;CG15389;CG33955;CG7245;CT35436;CT35437;eys;fibropellin fruit fly Drosophila melanogaster The D. melanogaster gene CG15388 is reported here. It encodes a product with putative receptor activity putatively involved in cell proliferation which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains a calcium-binding EGF-like domain. It has been mapped cytologically to 22E1. There is one recorded allele, which is wild-type. CG15388 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031414
4869 CG1542 fruit fly Drosophila melanogaster The D. melanogaster gene CG1542 is reported here. It encodes a product with molecular_function unknown involved in processing of 27S pre-rRNA which is a component of the nucleolus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 100B6--7. There is one recorded allele, which is wild-type. CG1542 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039828
4870 CG15434 fruit fly Drosophila melanogaster The D. melanogaster gene CG15434 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 24F3. There is one recorded allele, which is wild-type. CG15434 is discussed in 3 references (excluding sequence accessions), dated between 2001 and 2003. These include at least one molecular study. FB FBgn0040705
4875 CG15455 fruit fly Drosophila melanogaster The D. melanogaster gene CG15455 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains an acute myeloid leukemia 1 protein (AML 1)/Runt. It has been mapped cytologically to 19D2. There is one recorded allele, which is wild-type. CG15455 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031121
4876 CG15458 fruit fly Drosophila melanogaster The D. melanogaster gene CG15458 is reported here. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 19C6. There is one recorded allele, which is wild-type. CG15458 is discussed in 2 references (excluding sequence accessions), both dating from 2003. FB FBgn0040651
4880 RpS28a CG15527 fruit fly Drosophila melanogaster The D. melanogaster gene RpS28a is reported here. It has also been known in FlyBase as CG15527. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein S28e. It has been mapped cytologically to 99D2. There is one recorded allele, which is wild-type. RpS28a is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0039739
4892 CG15636 fruit fly Drosophila melanogaster The D. melanogaster gene CG15636 is reported here. It encodes a product with DNA binding which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a chromo domain. It has been mapped cytologically to 25A1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG15636 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031613
4896 CG15696 fruit fly Drosophila melanogaster The D. melanogaster gene CG15696 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 93A2. There is one recorded allele, which is wild-type. CG15696 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0038833
4897 RpS30 anon-EST:Posey127;CG15697;S30 fruit fly Drosophila melanogaster The D. melanogaster gene RpS30 is reported here. It has also been known in FlyBase as CG15697, anon-EST:Posey127 and anon-ESTPosey127. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 93A2. There is one recorded allele, which is wild-type. RpS30 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038834
4898 CG1571 fruit fly Drosophila melanogaster The D. melanogaster gene CG1571 is reported here. It encodes a product with motor activity putatively involved in microtubule-based movement which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7D5. There is one recorded allele, which is wild-type. CG1571 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029993
4904 CG15780 fruit fly Drosophila melanogaster The D. melanogaster gene CG15780 is reported here. It encodes a product with putative ATPase activity, coupled which is putatively a component of the myosin. It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 5A7--8. There is one recorded allele, which is wild-type. CG15780 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2000. FB FBgn0029776
4905 CG15782 CG15781;CG15783;CG33980 fruit fly Drosophila melanogaster The D. melanogaster gene CG15782 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 5A3--4. There is one recorded allele, which is wild-type. CG15782 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0029773
4906 CG15800 fruit fly Drosophila melanogaster The D. melanogaster gene CG15800 is reported here. It encodes a product with ubiquitin-protein ligase activity (EC:6.3.2.19) which is a component of the nuclear ubiquitin ligase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60A1. There is one recorded allele, which is wild-type. CG15800 is discussed in 2 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034904
4912 CG15831 fruit fly Drosophila melanogaster The D. melanogaster gene CG15831 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in cell motility which is putatively a component of the myosin. It has been sequenced. There is one recorded allele, which is wild-type. CG15831 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0040034
4916 CG1599 fruit fly Drosophila melanogaster The D. melanogaster gene CG1599 is reported here. It encodes a product with v-SNARE activity putatively involved in intracellular protein transport which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46B4. There is one recorded allele, which is wild-type. CG1599 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033452
4918 CG1620 fruit fly Drosophila melanogaster The D. melanogaster gene CG1620 is reported here. It encodes a product with ATP dependent DNA helicase activity involved in DNA replication which is a component of the replication fork. It has been sequenced and its amino acid sequence contains a myb DNA binding domain. It has been mapped cytologically to 43C5--6. There is one recorded allele, which is wild-type. CG1620 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033183
4919 CG1628 fruit fly Drosophila melanogaster The D. melanogaster gene CG1628 is reported here. It encodes a product with carrier activity involved in mitochondrial ornithine transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein). It has been mapped cytologically to 9D3--4. There are 3 recorded alleles: 2 in vitro constructs (none available from the public stock centers) and 1 wild-type. CG1628 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030218
4925 CG1646 ;Prp39 fruit fly Drosophila melanogaster The D. melanogaster gene CG1646 is reported here. It encodes a product with putative pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U1. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98E5. There is one recorded allele, which is wild-type. CG1646 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039600
4927 CG1662 fruit fly Drosophila melanogaster The D. melanogaster gene CG1662 is reported here. It encodes a product with putative receptor signaling protein activity which is a component of the integral to peroxisomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 11F1. There is one recorded allele, which is wild-type. CG1662 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0030481
4940 CG1673 fruit fly Drosophila melanogaster The D. melanogaster gene CG1673 is reported here. It encodes a product with branched-chain-amino-acid transaminase activity (EC:2.6.1.42) involved in branched chain family amino acid biosynthesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an aminotransferases class-IV. It has been mapped cytologically to 11F3. There is one recorded allele, which is wild-type. CG1673 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030482
4943 CG16736 fruit fly Drosophila melanogaster The D. melanogaster gene CG16736 is reported here. It encodes a product with putative carrier activity which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein). It has been mapped cytologically to 85D4. There is one recorded allele, which is wild-type. CG16736 is discussed in one reference (excluding sequence accessions), dating from 2000. FB FBgn0037668
4948 CG1677 fruit fly Drosophila melanogaster The D. melanogaster gene CG1677 is reported here. It encodes a product which is putatively a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger C-x8-C-x5-C-x3-H type. It has been mapped cytologically to 7A8--B2. There is one recorded allele, which is wild-type. CG1677 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029941
4952 CG16801 ;NR2E3;PNR fruit fly Drosophila melanogaster The D. melanogaster gene CG16801 is reported here. It encodes a product with steroid hormone receptor activity putatively involved in intracellular signaling cascade which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a vitamin D receptor, a ligand-binding domain of nuclear hormone receptor, a C4-type steroid receptor zinc finger and a steroid hormone receptor. It has been mapped cytologically to 51F7. There is one recorded allele, which is wild-type. CG16801 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0034012
4956 CG16832 fruit fly Drosophila melanogaster The D. melanogaster gene CG16832 is reported here. It encodes a product with transmembrane receptor activity which is a component of the plasma membrane. It has been sequenced. There is one recorded allele, which is wild-type. CG16832 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035814
4958 CG16837 fruit fly Drosophila melanogaster The D. melanogaster gene CG16837 is reported here. It encodes a product with putative ATPase activity, coupled putatively involved in microtubule-based movement which is putatively a component of the dynein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60D1. There is one recorded allele, which is wild-type. CG16837 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035009
4963 CG16899 ;Dmcg16899 fruit fly Drosophila melanogaster The D. melanogaster gene CG16899 is reported here. It encodes a product with transcription factor activity putatively involved in cellular defense response which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type and a fork head domain. It has been mapped cytologically to 85E5. There is one recorded allele, which is wild-type. CG16899 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037735
4964 CG16903 anon-WO03040301.211;EG:67A9.2 fruit fly Drosophila melanogaster The D. melanogaster gene CG16903 is reported here. It has also been known in FlyBase as EG:67A9.2. It encodes a product with general RNA polymerase II transcription factor activity putatively involved in nuclear mRNA splicing, via spliceosome which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2C10. There is one recorded allele, which is wild-type. CG16903 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0040394
4965 CG16912 anon-EST:fe1E12;anon-fast-evolving-1E12 fruit fly Drosophila melanogaster The D. melanogaster gene CG16912 is reported here. It has also been known in FlyBase as anon-EST:fe1E12 and anon-fe1E12. It encodes a product with tyrosine-tRNA ligase activity (EC:6.1.1.1) putatively involved in tRNA aminoacylation for protein translation. It has been sequenced and its amino acid sequence contains an aminoacyl-transfer RNA synthetases class-I, a t-RNA synthetase, class Ib and a tyrosyl-tRNA synthetase. It has been mapped cytologically to 60E1. There is one recorded allele, which is wild-type. CG16912 is discussed in 6 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one molecular study. FB FBgn0035064
4968 CG16940 fruit fly Drosophila melanogaster The D. melanogaster gene CG16940 is reported here. It encodes a product with exoribonuclease II activity (EC:3.1.13.1) putatively involved in RNA catabolism which is a component of the nuclear exosome (RNase complex). It has been sequenced and its amino acid sequence contains a ribonuclease II domain. It has been mapped cytologically to 61B2. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG16940 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least 2 molecular studies. FB FBgn0035111
4969 CG16941 ;SF3a120 fruit fly Drosophila melanogaster The D. melanogaster gene CG16941 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U2. It has been sequenced and its amino acid sequence contains a SWAP / SURP. It has been mapped cytologically to 89E6--7. There is one recorded allele, which is wild-type. CG16941 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0038464
4970 CG16954 fruit fly Drosophila melanogaster The D. melanogaster gene CG16954 is reported here. It encodes a product with chaperone activity involved in 'de novo' protein folding which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 34C1. There is one recorded allele, which is wild-type. CG16954 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0032525
4988 CG17036 fruit fly Drosophila melanogaster The D. melanogaster gene CG17036 is reported here. It encodes a product with reduced folate carrier activity putatively involved in coenzyme and prosthetic group metabolism which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains a reduced folate carrier. It has been mapped cytologically to 33F3. There is one recorded allele, which is wild-type. CG17036 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0032449
4994 CG17100 AAF24476.1;GM05287 fruit fly Drosophila melanogaster The D. melanogaster gene CG17100 is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in regulation of transcription which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a helix-loop-helix dimerization domain and an orange domain. It has been mapped cytologically to 86B3. There is one recorded allele, which is wild-type. CG17100 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2001. These include at least 2 molecular studies. FB FBgn0037813
4997 CG17118 fruit fly Drosophila melanogaster The D. melanogaster gene CG17118 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 32A5. There is one recorded allele, which is wild-type. CG17118 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2001. These include at least 2 molecular studies. FB FBgn0032291
4998 CG17119 fruit fly Drosophila melanogaster The D. melanogaster gene CG17119 is reported here. It encodes a product with L-cystine transporter activity involved in L-cystine transport which is a component of the lysosomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 94D10. There is one recorded allele, which is wild-type. CG17119 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039045
5002 CG17137 fruit fly Drosophila melanogaster The D. melanogaster gene CG17137 is reported here. It encodes a product with voltage-dependent ion-selective channel activity involved in mitochondrial transport which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an eukaryotic porin. It has been mapped cytologically to 32B1. There is one recorded allele, which is wild-type. CG17137 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0032308
5006 CG17150 fruit fly Drosophila melanogaster The D. melanogaster gene CG17150 is reported here. It encodes a product with motor activity putatively involved in microtubule-based movement which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64C1--2. There is one recorded allele, which is wild-type. CG17150 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035581
5015 CG17202 BcDNA:RH21090 fruit fly Drosophila melanogaster The D. melanogaster gene CG17202 is reported here. It has also been known in FlyBase as BcDNA:RH21090. It encodes a product with protein binding involved in biological_process unknown which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 87B9. There is one recorded allele, which is wild-type. CG17202 is discussed in 2 references (excluding sequence accessions), dated between 2000 and 2002. These include at least one molecular study. FB FBgn0038043
5016 CG17209 fruit fly Drosophila melanogaster The D. melanogaster gene CG17209 is reported here. It encodes a product with DNA-directed RNA polymerase activity (EC:2.7.7.6) involved in transcription from Pol III promoter which is a component of the DNA-directed RNA polymerase III complex. It has been sequenced and its amino acid sequence contains a RNA polymerase, α subunit and a RNA polymerase A/β'/A. It has been mapped cytologically to 13E14--15. There is one recorded allele, which is wild-type. CG17209 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030687
5020 CG17237 BcDNA:AT15471;DmAAF51272 fruit fly Drosophila melanogaster The D. melanogaster gene CG17237 is reported here. It has also been known in FlyBase as BcDNA:AT15471. It encodes a product with putative ATPase activity, coupled which is putatively a component of the myosin. It has been sequenced and its amino acid sequence contains a EF-hand family. It has been mapped cytologically to 22D6. There is one recorded allele, which is wild-type. CG17237 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031410
5022 CG1724 BcDNA:AT13347 fruit fly Drosophila melanogaster The D. melanogaster gene CG1724 is reported here. It has also been known in FlyBase as BcDNA:AT13347. It encodes a product with protein translocase activity involved in protein-mitochondrial targeting which is a component of the mitochondrial inner membrane presequence translocase complex. It has been sequenced and its amino acid sequence contains a mitochondrial import inner membrane translocase subunit Tim17. It has been mapped cytologically to 19F2. There is one recorded allele, which is wild-type. CG1724 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031164
5025 CG17266 fruit fly Drosophila melanogaster The D. melanogaster gene CG17266 is reported here. It encodes a product with peptidyl-prolyl cis-trans isomerase activity (EC:5.2.1.8) involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 42C3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG17266 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0033089
5029 CG17274 ;CT35907 fruit fly Drosophila melanogaster The D. melanogaster gene CG17274 is reported here. It encodes a product with putative glutamate-gated ion channel activity which is putatively a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an ionotropic glutamate receptor. It has been mapped cytologically to 93A2. There is one recorded allele, which is wild-type. CG17274 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2000. These include at least one molecular study. FB FBgn0038835
5030 CG17280 BcDNA:RH03295;VIa fruit fly Drosophila melanogaster The D. melanogaster gene CG17280 is reported here. It has also been known in FlyBase as BcDNA:RH03295. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome c oxidase, subunit VIa. It has been mapped cytologically to 59E3. There is one recorded allele, which is wild-type. CG17280 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034877
5033 CG17293 fruit fly Drosophila melanogaster The D. melanogaster gene CG17293 is reported here. It encodes a product with microtubule severing activity which is a component of the katanin. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 29B2--3. There is one recorded allele, which is wild-type. CG17293 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032030
5035 CG17301 BcDNA:AT30033 fruit fly Drosophila melanogaster The D. melanogaster gene CG17301 is reported here. It has also been known in FlyBase as BcDNA:AT30033. It encodes a product with putative peptidase activity (EC:3.4.-.-) involved in ubiquitin-dependent protein catabolism which is a component of the proteasome core complex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a multispecific proteases of the proteasome. It has been mapped cytologically to 23A2. There is one recorded allele, which is wild-type. CG17301 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031442
5036 CG17302 anon-WO0140519.122 fruit fly Drosophila melanogaster The D. melanogaster gene CG17302 is reported here. It encodes a product with putative peptidase activity (EC:3.4.-.-) involved in ubiquitin-dependent protein catabolism which is a component of the proteasome core complex (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 23A2. There is one recorded allele, which is wild-type. CG17302 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031443
5041 CG17328 BG:DS02740.8;DS02740.8 fruit fly Drosophila melanogaster The D. melanogaster gene CG17328 is reported here. It has also been known in FlyBase as BG:DS02740.8. It encodes a product with nucleic acid binding putatively involved in cell proliferation which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 35F6--7. There is one recorded allele, which is wild-type. CG17328 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0028895
5042 CG17331 ;GC17331 fruit fly Drosophila melanogaster The D. melanogaster gene CG17331 is reported here. It encodes a product with endopeptidase activity putatively involved in proteolysis and peptidolysis which is a component of the proteasome core complex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a proteasome B-type subunit and a multispecific proteases of the proteasome. It has been mapped cytologically to 36A12. There is one recorded allele, which is wild-type. CG17331 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032596
5044 CG17347 ;dynactin;dynactin, p27 subunit;P27 DYNACTIN;p27 subunit fruit fly Drosophila melanogaster The D. melanogaster gene CG17347 is reported here. It encodes a product putatively involved in microtubule-based movement which is putatively a component of the dynactin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 37C1. There is one recorded allele, which is wild-type. CG17347 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0032761
5048 CG17454 ;SPF30 fruit fly Drosophila melanogaster The D. melanogaster gene CG17454 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a tudor domain. There is one recorded allele, which is wild-type. CG17454 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0039977
5049 CG1746 anon-EST:Posey224 fruit fly Drosophila melanogaster The D. melanogaster gene CG1746 is reported here. It has also been known in FlyBase as anon-EST:Posey224. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) involved in proton transport which is a component of the proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukarya). It has been sequenced and its amino acid sequence contains an eubacterial and plasma membrane ATP synthase subunit C and a ATP synthase subunit C. It has been mapped cytologically to 100B7. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG1746 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039830
5050 CG17462 AAF56369 fruit fly Drosophila melanogaster The D. melanogaster gene CG17462 is reported here. It encodes a product with sigma DNA polymerase activity involved in sister chromatid cohesion which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a PAP/25A core domain and a PAP/25A associated domain. It has been mapped cytologically to 96B9. There is one recorded allele, which is wild-type. CG17462 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0039251
5055 CG17493 ;CG40016 fruit fly Drosophila melanogaster The D. melanogaster gene CG17493 is reported here. It encodes a product with calcium ion binding putatively involved in calcium-mediated signaling which is putatively a component of the cytoskeleton. It has been sequenced and its amino acid sequence contains a EF-hand family. There is one recorded allele, which is wild-type. CG17493 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0040010
5056 CG17498 fruit fly Drosophila melanogaster The D. melanogaster gene CG17498 is reported here. It encodes a product involved in mitotic spindle checkpoint which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64E11--12. There is one recorded allele, which is wild-type. CG17498 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035640
5058 CG1751 fruit fly Drosophila melanogaster The D. melanogaster gene CG1751 is reported here. It encodes a product with signal peptidase activity involved in signal peptide processing which is a component of the integral to membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 10B15--16. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. CG1751 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0030306
5065 CG17528 CAMK-like;CG40283 fruit fly Drosophila melanogaster The D. melanogaster gene CG17528 is reported here. It has also been known in FlyBase as CG40283. It encodes a product with protein serine/threonine kinase activity involved in protein amino acid phosphorylation which is putatively a component of the microtubule associated complex. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a doublecortin. There is one recorded allele, which is wild-type. CG17528 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0032999
5069 CG17540 fruit fly Drosophila melanogaster The D. melanogaster gene CG17540 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a D111/G-patch domain. There is one recorded allele, which is wild-type. CG17540 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0040024
5087 CG17691 fruit fly Drosophila melanogaster The D. melanogaster gene CG17691 is reported here. It encodes a product with 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity (EC:1.2.4.4) involved in acyl-CoA biosynthesis which is a component of the 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex. It has been sequenced and its amino acid sequence is also available. There is one recorded allele, which is wild-type. CG17691 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039993
5099 CG17760 BcDNA:SD21019 fruit fly Drosophila melanogaster The D. melanogaster gene CG17760 is reported here. It has also been known in FlyBase as BcDNA:SD21019. It encodes a product with heterotrimeric G-protein GTPase activity (EC:3.6.5.1) putatively involved in G-protein coupled receptor protein signaling pathway which is a component of the heterotrimeric G-protein complex. It has been sequenced and its amino acid sequence contains a guanine nucleotide binding protein (G-protein), α subunit. It has been mapped cytologically to 49B9--10. There is one recorded allele, which is wild-type. CG17760 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033756
5100 CG17764 fruit fly Drosophila melanogaster The D. melanogaster gene CG17764 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 4F4. There is one recorded allele, which is wild-type. CG17764 is discussed in 2 references (excluding sequence accessions), both dating from 2000. These include at least one molecular study. FB FBgn0029751
5102 CG17766 ;EG:86E4.3 fruit fly Drosophila melanogaster The D. melanogaster gene CG17766 is reported here. It has also been known in FlyBase as EG:86E4.3. It encodes a product with putative heterotrimeric G-protein GTPase activity (EC:3.6.5.1) putatively involved in G-protein coupled receptor protein signaling pathway which is putatively a component of the heterotrimeric G-protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2B15. There is one recorded allele, which is wild-type. CG17766 is discussed in 7 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one molecular study. FB FBgn0023510
5108 CG17838 AI945337;anon-WO0118547.613;CG31195;l(3)03806 fruit fly Drosophila melanogaster The D. melanogaster gene CG17838 is reported here. It has also been known in FlyBase as l(3)03806. It encodes a product with putative RNA binding which is a component of the heterogeneous nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 92F12--93A1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. CG17838 is discussed in 14 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 molecular studies. FB FBgn0038826
5110 CG17856 fruit fly Drosophila melanogaster The D. melanogaster gene CG17856 is reported here. It encodes a product with ubiquinol-cytochrome-c reductase activity (EC:1.10.2.2) involved in mitochondrial electron transport, ubiquinol to cytochrome c which is a component of the ubiquinol-cytochrome-c reductase complex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a cytochrome bd ubiquinol oxidase, 14kD subunit. It has been mapped cytologically to 98C3. There is one recorded allele, which is wild-type. CG17856 is discussed in 4 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0039576
5111 CG1789 fruit fly Drosophila melanogaster The D. melanogaster gene CG1789 is reported here. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the small nucleolar ribonucleoprotein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 8A3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG1789 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0030063
5112 CG17896 ;EG:171D11.1 fruit fly Drosophila melanogaster The D. melanogaster gene CG17896 is reported here. It has also been known in FlyBase as EG:171D11.1. It encodes a product with methylmalonate-semialdehyde dehydrogenase (acylating) activity (EC:1.2.1.27) involved in valine metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains an aldehyde dehydrogenase family. It has been mapped cytologically to 1B5. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG17896 is discussed in 13 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 molecular studies. FB FBgn0023537
5116 CG17922 fruit fly Drosophila melanogaster The D. melanogaster gene CG17922 is reported here. It encodes a product with intracellular cyclic nucleotide activated cation channel activity putatively involved in cation transport which is a component of the intracellular cyclic nucleotide activated cation channel complex. It has been sequenced and its amino acid sequence contains a potassium channel and a cyclic nucleotide gated / K+ ion channel TM region. It has been mapped cytologically to 57F9. There is one recorded allele, which is wild-type. CG17922 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034656
5117 CG17923 ;JYalpha fruit fly Drosophila melanogaster The D. melanogaster gene CG17923 is reported here. It encodes a product with sodium/potassium-exchanging ATPase activity (EC:3.6.3.9) putatively involved in calcium ion homeostasis which is a component of the sodium/potassium-exchanging ATPase complex. It has been sequenced and its amino acid sequence contains a H+/K+ and Na+/K+ transporting ATPase, a haloacid dehalogenase/epoxide hydrolase family and a E1-E2 ATPases. It has been mapped cytologically to 101F1. There is one recorded allele, which is wild-type. CG17923 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0040037
5121 RpL38 41Af;41Ag;BcDNA:RE42506;CG18001;CG40278;E-2b;Enhancer on chromosome 2, complementation group b;GroupIV;l(2)41Af;l(2)41Ag;l(2)41Ai;l(2)EMS4-72;l(2)EMS45-72;l(2R)A';lethal(2)41Af;M(2)41A;M(2)S2;M(2)S3;Minute(2)41A;Nipped fruit fly Drosophila melanogaster The D. melanogaster gene RpL38 is reported here. It has also been known in FlyBase as BcDNA:RE42506 and CG18001. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal L38e protein family. There is one recorded allele, which is wild-type. RpL38 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0040007
5137 CG18193 ;VIIa fruit fly Drosophila melanogaster The D. melanogaster gene CG18193 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 84F13. There is one recorded allele, which is wild-type. CG18193 is discussed in 3 references (excluding sequence accessions), dated between 2001 and 2003. These include at least one molecular study. FB FBgn0037579
5139 CG1824 fruit fly Drosophila melanogaster The D. melanogaster gene CG1824 is reported here. It encodes a product with ATP-binding cassette (ABC) transporter activity (EC:3.6.3.-) putatively involved in defense response which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a ABC transporter transmembrane region, a ABC transporter and a AAA ATPase superfamily. It has been mapped cytologically to 11B2. There is one recorded allele, which is wild-type. CG1824 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030403
5142 CG18317 fruit fly Drosophila melanogaster The D. melanogaster gene CG18317 is reported here. It encodes a product with putative carrier activity putatively involved in transport which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial brown fat uncoupling domain and a mitochondrial carrier domain. It has been mapped cytologically to 22B1. There is one recorded allele, which is wild-type. CG18317 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0031359
5143 CG18324 fruit fly Drosophila melanogaster The D. melanogaster gene CG18324 is reported here. It encodes a product with putative carrier activity putatively involved in transport which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein). It has been mapped cytologically to 50E1. There is one recorded allele, which is wild-type. CG18324 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0033905
5144 CG18327 fruit fly Drosophila melanogaster The D. melanogaster gene CG18327 is reported here. It encodes a product with putative carrier activity putatively involved in transport which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein) and an adenine nucleotide translocator 1. It has been mapped cytologically to 50E1. There is one recorded allele, which is wild-type. CG18327 is discussed in 2 references (excluding sequence accessions), dated between 2000 and 2003. FB FBgn0033904
5145 CG18347 fruit fly Drosophila melanogaster The D. melanogaster gene CG18347 is reported here. It encodes a product with putative carrier activity putatively involved in lipid metabolism which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial carrier domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 87A3--4. There is one recorded allele, which is wild-type. CG18347 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0037969
5146 CG18363 fruit fly Drosophila melanogaster The D. melanogaster gene CG18363 is reported here. It encodes a product with putative carrier activity putatively involved in cation transport which is putatively a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial brown fat uncoupling domain and a mitochondrial carrier domain. It has been mapped cytologically to 75D6. There is one recorded allele, which is wild-type. CG18363 is discussed in 2 references (excluding sequence accessions), dated between 2000 and 2003. FB FBgn0036808
5148 CG18418 anon-WO0140519.190 fruit fly Drosophila melanogaster The D. melanogaster gene CG18418 is reported here. It encodes a product with oxoglutarate:malate antiporter activity involved in mitochondrial alpha-ketoglutarate/malate transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial brown fat uncoupling domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 64B13. There is one recorded allele, which is wild-type. CG18418 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0035568
5159 CG18591 BcDNA:GM19936 fruit fly Drosophila melanogaster The D. melanogaster gene CG18591 is reported here. It has also been known in FlyBase as BcDNA:GM19936. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a small nuclear ribonucleoprotein (Sm protein). It has been mapped cytologically to 28D2. There is one recorded allele, which is wild-type. CG18591 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0031962
5161 CG18624 CG15328 fruit fly Drosophila melanogaster The D. melanogaster gene CG18624 is reported here. It has also been known in FlyBase as CG15328. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 7C2. There is one recorded allele, which is wild-type. CG18624 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. FB FBgn0029971
5165 CG18656 ;CG33277;CG33278;CG33279 CG18656 fruit fly Drosophila melanogaster FB FBgn0035784
5170 CG18809 fruit fly Drosophila melanogaster The D. melanogaster gene CG18809 is reported here. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18E5. There is one recorded allele, which is wild-type. CG18809 is discussed in 4 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0042132
5171 RpS7 CG1883 fruit fly Drosophila melanogaster The D. melanogaster gene RpS7 is reported here. It has also been known in FlyBase as CG1883. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein S7E. It has been mapped cytologically to 99E2. There is one recorded allele, which is wild-type. RpS7 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039757
5176 CG1887 fruit fly Drosophila melanogaster The D. melanogaster gene CG1887 is reported here. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a CD36 family. It has been mapped cytologically to 62B9. There is one recorded allele, which is wild-type. CG1887 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035290
5182 CG1907 fruit fly Drosophila melanogaster The D. melanogaster gene CG1907 is reported here. It encodes a product with oxoglutarate:malate antiporter activity involved in mitochondrial alpha-ketoglutarate/malate transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein) and an adenine nucleotide translocator 1. It has been mapped cytologically to 99B5. There is one recorded allele, which is wild-type. CG1907 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039674
5185 CG1911 CAP-D2 fruit fly Drosophila melanogaster The D. melanogaster gene CG1911 is reported here. It encodes a product with putative nucleic acid binding involved in mitotic chromosome condensation which is a component of the condensin complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 99B7. There is one recorded allele, which is wild-type. CG1911 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039680
5187 CG1924 fruit fly Drosophila melanogaster The D. melanogaster gene CG1924 is reported here. It encodes a product with chaperone activity putatively involved in exocytosis which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains a calreticulin family. It has been mapped cytologically to 11A6. There is one recorded allele, which is wild-type. CG1924 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0030377
5190 CG1957 BcDNA:LD14168 fruit fly Drosophila melanogaster The D. melanogaster gene CG1957 is reported here. It has also been known in FlyBase as BcDNA:LD14168. It encodes a product with mRNA 3' UTR binding involved in mRNA cleavage which is a component of the mRNA cleavage and polyadenylation specificity factor complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98F5. There is one recorded allele, which is wild-type. CG1957 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0027873
5196 CG1970 fruit fly Drosophila melanogaster The D. melanogaster gene CG1970 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence contains a NADH-ubiquinone oxidoreductase 49Kd chain. It has been mapped cytologically to 102C2. There is one recorded allele, which is wild-type. CG1970 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039909
5197 CG1972 fruit fly Drosophila melanogaster The D. melanogaster gene CG1972 is reported here. It encodes a product with putative endoribonuclease activity involved in mRNA cleavage which is a component of the mRNA cleavage and polyadenylation specificity factor complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 99B10. There is one recorded allele, which is wild-type. CG1972 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0039691
5200 CG1994 ;l(1)G0020;p110 CG1994 fruit fly Drosophila melanogaster FB FBgn0030062
5203 CG2014 fruit fly Drosophila melanogaster The D. melanogaster gene CG2014 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence contains a respiratory-chain NADH dehydrogenase 20 Kd subunit. It has been mapped cytologically to 99B2. There is one recorded allele, which is wild-type. CG2014 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0039669
5205 CG2021 fruit fly Drosophila melanogaster The D. melanogaster gene CG2021 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a small nuclear ribonucleoprotein (Sm protein). It has been mapped cytologically to 62B4. There is one recorded allele, which is wild-type. CG2021 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035271
5206 CG2022 fruit fly Drosophila melanogaster The D. melanogaster gene CG2022 is reported here. It encodes a product with putative receptor signaling protein activity which is a component of the peroxisomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 82E4. There is one recorded allele, which is wild-type. CG2022 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0037292
5208 CG2031 ;Hpr1 fruit fly Drosophila melanogaster The D. melanogaster gene CG2031 is reported here. It encodes a product which is a component of the nucleoplasm. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 83C4. There is one recorded allele, which is wild-type. CG2031 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0037382
5215 CG2097 fruit fly Drosophila melanogaster The D. melanogaster gene CG2097 is reported here. It encodes a product involved in mRNA cleavage which is a component of the mRNA cleavage stimulating factor complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 83C1--2. There is one recorded allele, which is wild-type. CG2097 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0037371
5216 RpL35A anon-EST:Posey39;CG2099;L35a fruit fly Drosophila melanogaster The D. melanogaster gene RpL35A is reported here. It has also been known in FlyBase as CG2099 and anon-EST:Posey39. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a globin and a ribosomal protein L35Ae. It has been mapped cytologically to 83A4. There is one recorded allele, which is wild-type. RpL35A is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0037328
5223 CG2118 fruit fly Drosophila melanogaster The D. melanogaster gene CG2118 is reported here. It encodes a product with methylcrotonoyl-CoA carboxylase activity (EC:6.4.1.4) involved in leucine metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a carbamoyl-phosphate synthase. It has been mapped cytologically to 100D2. There is one recorded allele, which is wild-type. CG2118 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0039877
5225 CG2137 fruit fly Drosophila melanogaster The D. melanogaster gene CG2137 is reported here. It encodes a product with glycerol-3-phosphate dehydrogenase activity (EC:1.1.99.5) involved in glycerol metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a FAD-dependent glycerol-3-phosphate dehydrogenase and a EF-hand family. It has been mapped cytologically to 43D3. There is one recorded allele, which is wild-type. CG2137 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033190
5227 CG2156 fruit fly Drosophila melanogaster The D. melanogaster gene CG2156 is reported here. It encodes a product with nicotinic acetylcholine-activated cation-selective channel activity which is a component of the nicotinic acetylcholine-gated receptor-channel complex. It has been sequenced. There is one recorded allele, which is wild-type. CG2156 is discussed in 3 references (excluding sequence accessions), dated between 2001 and 2003. FB FBgn0030031
5228 CG2158 fruit fly Drosophila melanogaster The D. melanogaster gene CG2158 is reported here. It encodes a product with putative transporter activity putatively involved in protein targeting which is a component of the nuclear pore. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 44B3. There is one recorded allele, which is wild-type. CG2158 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0033264
5229 CG2165 BEST:CK01140;BEST:CK02288;CK01140;CK02288 fruit fly Drosophila melanogaster The D. melanogaster gene CG2165 is reported here. It has also been known in FlyBase as BEST:CK01140 and BEST:CK02288. It encodes a product with calcium-transporting ATPase activity (EC:3.6.3.8) putatively involved in calcium ion homeostasis which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains a haloacid dehalogenase/epoxide hydrolase family and a E1-E2 ATPases. It has been mapped cytologically to 102B5. There is one recorded allele, which is wild-type. CG2165 is discussed in 10 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 2 molecular studies. FB FBgn0025704
5239 CG2241 ;DmCG2241;Dm_Rpt6b fruit fly Drosophila melanogaster The D. melanogaster gene CG2241 is reported here. It encodes a product with ATPase activity involved in proteolysis and peptidolysis which is a component of the proteasome regulatory particle, base subcomplex (sensu Eukarya). It has been sequenced and its amino acid sequence contains a AAA ATPase superfamily. It has been mapped cytologically to 99F9--10. There is one recorded allele, which is wild-type. CG2241 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0039788
5241 CG2249 anon-EST:fe3A1;anon-fast-evolving-3A1;BcDNA:LD14731;VIIc fruit fly Drosophila melanogaster The D. melanogaster gene CG2249 is reported here. It has also been known in FlyBase as BcDNA:LD14731, anon-EST:fe3A1 and anon-fe3A1. It encodes a product with cytochrome-c oxidase activity (EC:1.9.3.1) involved in mitochondrial electron transport, cytochrome c to oxygen which is a component of the respiratory chain complex IV (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 46D8--9. There is one recorded allele, which is wild-type. CG2249 is discussed in 8 references (excluding sequence accessions), dated between 1997 and 2003. These include at least one molecular study. FB FBgn0040773
5246 CG2358 AF160889;BcDNA:GM04682;BG:DS00004.11;SPC 21-kDa-like fruit fly Drosophila melanogaster The D. melanogaster gene CG2358 is reported here. It has also been known in FlyBase as BG:DS00004.11 and BcDNA:GM04682. It encodes a product with signal peptidase activity involved in signal peptide processing which is a component of the signal peptidase complex. It has been sequenced and its amino acid sequence contains a signal peptidase and an eukaryotic signal peptidase (S26B) family. It has been mapped cytologically to 84A1. There is one recorded allele, which is wild-type. CG2358 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0026567
5249 CG2508 38C.54;cdc23 fruit fly Drosophila melanogaster The D. melanogaster gene CG2508 is reported here. It encodes a product with ubiquitin-protein ligase activity (EC:6.3.2.19) involved in mitotic anaphase which is a component of the anaphase-promoting complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 38C7--8. There is one recorded allele, which is wild-type. CG2508 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 3 molecular studies. FB FBgn0032863
5251 CG2543 fruit fly Drosophila melanogaster The D. melanogaster gene CG2543 is reported here. It encodes a product with tetrahydrofolylpolyglutamate synthase activity (EC:6.3.2.17) involved in tetrahydrofolylpolyglutamate biosynthesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a cytoplasmic peptidoglycan synthetases (MurC, MurD, MurE, MurF, and Mpl) and a folylpolyglutamate synthetase. It has been mapped cytologically to 11B3--4. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. CG2543 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030407
5257 CG2616 fruit fly Drosophila melanogaster The D. melanogaster gene CG2616 is reported here. It encodes a product with carrier activity putatively involved in transport which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein). It has been mapped cytologically to 84D13. There is one recorded allele, which is wild-type. CG2616 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0037512
5261 CG2658 anon-3Ba;Dm100G10.aj;EG:100G10.7;paraplegin_DROME fruit fly Drosophila melanogaster The D. melanogaster gene CG2658 is reported here. It has also been known in FlyBase as EG:100G10.7 and anon-3Ba. It encodes a product with ATPase activity involved in ATP-dependent proteolysis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a peptidase family M41 and a AAA ATPase superfamily. It has been mapped cytologically to 3B3. There are 4 recorded alleles: 3 in vitro constructs (none available from the public stock centers) and 1 wild-type. CG2658 is discussed in 18 references (excluding sequence accessions), dated between 1984 and 2003. These include at least one study of wild-type function and 5 molecular studies. FB FBgn0024992
5263 CG2678 anon-84Eb;B;transcript B fruit fly Drosophila melanogaster The D. melanogaster gene CG2678 is reported here. It has also been known in FlyBase as anon-84Eb. It encodes a product with transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 84E5. There are 3 recorded alleles: 2 in vitro constructs (none available from the public stock centers) and 1 wild-type. CG2678 is discussed in 9 references (excluding sequence accessions), dated between 1988 and 2003. These include at least one study of wild-type function and 4 molecular studies. FB FBgn0014931
5265 CG2736 fruit fly Drosophila melanogaster The D. melanogaster gene CG2736 is reported here. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a CD36 family. It has been mapped cytologically to 60E10--11. There is one recorded allele, which is wild-type. CG2736 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035090
5270 CG2789 anon-EST:Posey116 fruit fly Drosophila melanogaster The D. melanogaster gene CG2789 is reported here. It has also been known in FlyBase as anon-EST:Posey116 and anon-ESTPosey116. It encodes a product with benzodiazepine receptor activity putatively involved in coenzyme and prosthetic group metabolism which is a component of the mitochondrial membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 21E1. There is one recorded allele, which is wild-type. CG2789 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031263
5272 CG2807 anon-21Cd fruit fly Drosophila melanogaster The D. melanogaster gene CG2807 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U2. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 21E2. There is one recorded allele, which is wild-type. CG2807 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031266
5273 CG2808 fruit fly Drosophila melanogaster The D. melanogaster gene CG2808 is reported here. It encodes a product with transcription factor activity which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 24B1. There is one recorded allele, which is wild-type. CG2808 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031556
5274 CG2812 fruit fly Drosophila melanogaster The D. melanogaster gene CG2812 is reported here. It encodes a product with heterotrimeric G-protein GTPase activity (EC:3.6.5.1) which is a component of the heterotrimeric G-protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60A11. There is one recorded allele, which is wild-type. CG2812 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034931
5276 CG2829 anon-WO03040301.114;anon-WO03040301.116;BcDNA:GH07910;CG32782;CG33219;l(1)G0054;tlk fruit fly Drosophila melanogaster The D. melanogaster gene CG2829 is reported here. It has also been known in FlyBase as BcDNA:GH07910. It encodes a product with protein kinase activity (EC:2.7.1.37) involved in protein amino acid phosphorylation. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase and a serine/Threonine protein kinase family active site. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG2829 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2004. FB FBgn0028489
5278 CG2857 fruit fly Drosophila melanogaster The D. melanogaster gene CG2857 is reported here. It encodes a product with oxidative phosphorylation uncoupler activity putatively involved in cation transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a mitochondrial carrier domain and an adenine nucleotide translocator 1. It has been mapped cytologically to 60E5. There is one recorded allele, which is wild-type. CG2857 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0035078
5290 CG2968 anon-WO03040301.109;anon-WO03040301.110;l(1)G0230 CG2968 fruit fly Drosophila melanogaster FB FBgn0030184
5295 RpS28b CG2998 fruit fly Drosophila melanogaster The D. melanogaster gene RpS28b is reported here. It has also been known in FlyBase as CG2998. It encodes a product with structural constituent of ribosome putatively involved in protein biosynthesis which is a component of the cytosolic small ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein S28e. It has been mapped cytologically to 8E9. There is one recorded allele, which is wild-type. RpS28b is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0030136
5307 CG3004 fruit fly Drosophila melanogaster The D. melanogaster gene CG3004 is reported here. It encodes a product with heterotrimeric G-protein GTPase activity (EC:3.6.5.1) putatively involved in rRNA metabolism which is a component of the heterotrimeric G-protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 8F1. There is one recorded allele, which is wild-type. CG3004 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0030142
5313 CG30054 fruit fly Drosophila melanogaster The D. melanogaster gene CG30054 is reported here. It encodes a product with GTP binding putatively involved in G-protein coupled receptor protein signaling pathway which is a component of the heterotrimeric G-protein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 49B9. There is one recorded allele, which is wild-type. CG30054 is discussed in 3 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0050054
5337 CG3011 fruit fly Drosophila melanogaster The D. melanogaster gene CG3011 is reported here. It encodes a product with glycine hydroxymethyltransferase activity (EC:2.1.2.1) involved in L-serine biosynthesis which is a component of the mitochondrion. It has been sequenced and its amino acid sequence contains a serine hydroxymethyltransferase (SHMT). It has been mapped cytologically to 5C7. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG3011 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029823
5344 CG30122 CG18610;CG5477 fruit fly Drosophila melanogaster The D. melanogaster gene CG30122 is reported here. It has also been known in FlyBase as CG18610 and CG5477. It encodes a product with RNA binding putatively involved in RNA elongation from Pol II promoter which is a component of the heterogeneous nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a SAP domain. It has been mapped cytologically to 55E3. There is one recorded allele, which is wild-type. CG30122 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0050122
5363 CG3033 fruit fly Drosophila melanogaster The D. melanogaster gene CG3033 is reported here. It encodes a product involved in attachment of GPI anchor to protein which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 5C5. There is one recorded allele, which is wild-type. CG3033 is discussed in 2 references (excluding sequence accessions), dated between 1999 and 2000. These include at least one molecular study. FB FBgn0029818
5381 CG3058 BcDNA:RE13747 fruit fly Drosophila melanogaster The D. melanogaster gene CG3058 is reported here. It has also been known in FlyBase as BcDNA:RE13747. It encodes a product involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence contains a thioredoxin. It has been mapped cytologically to 24F1. There is one recorded allele, which is wild-type. CG3058 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031601
5383 CG3071 ;EG:25E8.3 fruit fly Drosophila melanogaster The D. melanogaster gene CG3071 is reported here. It has also been known in FlyBase as EG:25E8.3. It encodes a product putatively involved in retrograde transport, Golgi to ER which is putatively a component of the COPI vesicle coat. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 2F2. There is one recorded allele, which is wild-type. CG3071 is discussed in 7 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 2 molecular studies. FB FBgn0023527
5386 CG3075 ;NF-YC-like fruit fly Drosophila melanogaster The D. melanogaster gene CG3075 is reported here. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a histone-fold/TFIID-TAF/NF-Y domain. It has been mapped cytologically to 6D3. There is one recorded allele, which is wild-type. CG3075 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029905
5399 CG31075 ;CG6309;CT19744 fruit fly Drosophila melanogaster The D. melanogaster gene CG31075 is reported here. It has also been known in FlyBase as CG6309. It encodes a product with aldehyde dehydrogenase (NAD) activity (EC:1.2.1.3) involved in pyruvate metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 97D12. There is one recorded allele, which is wild-type. CG31075 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051075
5414 CG31159 ;CG6943 fruit fly Drosophila melanogaster The D. melanogaster gene CG31159 is reported here. It has also been known in FlyBase as CG6943. It encodes a product with translation elongation factor activity involved in translational elongation which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 94B6. There is one recorded allele, which is wild-type. CG31159 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051159
5421 CG31184 BcDNA:RE11655;CG5926 fruit fly Drosophila melanogaster The D. melanogaster gene CG31184 is reported here. It has also been known in FlyBase as BcDNA:RE11655 and CG5926. It encodes a product with RNA binding involved in nuclear mRNA splicing, via spliceosome which is a component of the small nuclear ribonucleoprotein complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 95D5. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG31184 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051184
5423 CG31190 CG12536;CG8106;CT33960;Dscam-like fruit fly Drosophila melanogaster The D. melanogaster gene CG31190 is reported here. It has also been known in FlyBase as CG12536 and CG8106. It encodes a product involved in cell adhesion which is a component of the plasma membrane. It has been sequenced and its amino acid sequence contains an immunoglobulin and major histocompatibility complex domain, an immunoglobulin C-2 type and an immunoglobulin-like. It has been mapped cytologically to 90B1. There is one recorded allele, which is wild-type. CG31190 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0051190
5428 CG3121 anon-WO0140519.109 fruit fly Drosophila melanogaster The D. melanogaster gene CG3121 is reported here. It encodes a product with putative microtubule binding putatively involved in microtubule-based process which is putatively a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 60B3. There is one recorded allele, which is wild-type. CG3121 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0034957
5431 CG31217 anon-X;BACN33B1.1;CG10100;CG17557;CG2759;CG3585;CG5123;CT28389;DMWHITE;Dmx;e(g);EG:BACN33B1.1;enhancer of garnet;head involution defect;Head involution defective;hid;Hid1;l(3)05014;LDL;Ldlr;low density lipoprotein receptor-like 'a' repeats;m(g);modifier of garnet;predicted gene W;predicted gene X;Ser89E;Serine protease like 89E;Serine protease-like;SP172;SP53;W;w(AT)13;wrinkler;X fruit fly Drosophila melanogaster The D. melanogaster gene CG31217 is reported here. It has also been known in FlyBase as Ldlr and Ser89E. It encodes a product with scavenger receptor activity involved in proteolysis and peptidolysis. It has been sequenced and its amino acid sequence contains a serine proteases, trypsin family. It has been mapped cytologically to 89D6. There is one recorded allele, which is wild-type. CG31217 is discussed in 18 references (excluding sequence accessions), dated between 1992 and 2003. These include at least 3 molecular studies. FB FBgn0051217
5435 CG31224 CG17796;CG7696;l(3)c00083;lethal (3) c00083 fruit fly Drosophila melanogaster The D. melanogaster gene CG31224 is reported here. It has also been known in FlyBase as CG17796 and CG7696. It encodes a product with nucleic acid binding putatively involved in cell proliferation. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 91B8. There is one recorded allele, which is wild-type. CG31224 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051224
5436 CG31229 fruit fly Drosophila melanogaster The D. melanogaster gene CG31229 is reported here. It encodes a product with protein translocase activity involved in protein-mitochondrial targeting which is a component of the mitochondrial inner membrane presequence translocase complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 91B8. There is one recorded allele, which is wild-type. CG31229 is discussed in 4 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0051229
5444 CG31272 ;CG6529 fruit fly Drosophila melanogaster The D. melanogaster gene CG31272 is reported here. It has also been known in FlyBase as CG6529. It encodes a product with transporter activity involved in transport which is a component of the synaptic vesicle membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 86C5. There is one recorded allele, which is wild-type. CG31272 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051272
5445 CG31275 BcDNA:GH08635;CG14908;late transcript fruit fly Drosophila melanogaster The D. melanogaster gene CG31275 is reported here. It has also been known in FlyBase as BcDNA:GH08635. It encodes a product with putative ATPase activity, coupled involved in microtubule-based movement which is a component of the cytoskeleton. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 89E1. There is one recorded allele, which is wild-type. CG31275 is discussed in 12 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 2 molecular studies. FB FBgn0063261
5448 CG31305 fruit fly Drosophila melanogaster The D. melanogaster gene cassette CG31305 is reported here. It has been sequenced. It has been mapped cytologically to 86E10. There is one recorded allele, which is wild-type. CG31305 is discussed in 6 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0051305
5454 CG31358 CG17424;CG18141;CG18142 fruit fly Drosophila melanogaster The D. melanogaster gene CG31358 is reported here. It has also been known in FlyBase as CG17424, CG18141 and CG18142. It encodes a product with putative structural constituent of cytoskeleton putatively involved in cytoskeleton organization and biogenesis which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 87A5. There is one recorded allele, which is wild-type. CG31358 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0051358
5456 CG31365 ;CG4639 fruit fly Drosophila melanogaster The D. melanogaster gene CG31365 is reported here. It has also been known in FlyBase as CG4639. It encodes a product with nucleic acid binding putatively involved in cell proliferation which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 94E1. There is one recorded allele, which is wild-type. CG31365 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0051365
5457 CG31367 CG15187 fruit fly Drosophila melanogaster The D. melanogaster gene CG31367 is reported here. It has also been known in FlyBase as CG15187. It encodes a product with transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 83E4. There is one recorded allele, which is wild-type. CG31367 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051367
5459 CG31388 BcDNA:GH10523;CG17722;CG5135 fruit fly Drosophila melanogaster The D. melanogaster gene CG31388 is reported here. It has also been known in FlyBase as BcDNA:GH10523, CG17722 and CG5135. It encodes a product with nucleic acid binding which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 86D8. There is one recorded allele, which is wild-type. CG31388 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2002. These include at least one molecular study. FB FBgn0051388
5466 CG31441 ;CG5135 fruit fly Drosophila melanogaster The D. melanogaster gene CG31441 is reported here. It has also been known in FlyBase as CG5135. It encodes a product with nucleic acid binding putatively involved in cell proliferation which is a component of the nucleus. It has been sequenced. It has been mapped cytologically to 86D8. There is one recorded allele, which is wild-type. CG31441 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051441
5482 CG3156 ;EG:171D11.2 fruit fly Drosophila melanogaster The D. melanogaster gene CG3156 is reported here. It has also been known in FlyBase as EG:171D11.2. It encodes a product with ATP-binding cassette (ABC) transporter activity (EC:3.6.3.-) involved in mitochondrial transport which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence contains a ABC transporter transmembrane region, a ABC transporter and a AAA ATPase superfamily. It has been mapped cytologically to 1B5. There is one recorded allele, which is wild-type. CG3156 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0023536
5483 CG31612 CG11631;CG11632 fruit fly Drosophila melanogaster The D. melanogaster gene CG31612 is reported here. It has also been known in FlyBase as CG11631 and CG11632. It encodes a product with nucleic acid binding. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 40A2--3. There is one recorded allele, which is wild-type. CG31612 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051612
5485 CG3162 fruit fly Drosophila melanogaster The D. melanogaster gene CG3162 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U2. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 59D2. There is one recorded allele, which is wild-type. CG3162 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0034834
5486 CG31632 CG11243;CG17373 fruit fly Drosophila melanogaster The D. melanogaster gene CG31632 is reported here. It has also been known in FlyBase as CG11243 and CG17373. It encodes a product with nucleic acid binding putatively involved in cell proliferation which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type and a zn-finger CCHC type. It has been mapped cytologically to 27B3--4. There is one recorded allele, which is wild-type. CG31632 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051632
5490 CG31638 CG13764;CG9545 fruit fly Drosophila melanogaster The D. melanogaster gene CG31638 is reported here. It has also been known in FlyBase as CG13764 and CG9545. It encodes a product which is a component of the myosin. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 26D9. There is one recorded allele, which is wild-type. CG31638 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0051638
5494 CG31648 ;CG6922 fruit fly Drosophila melanogaster The D. melanogaster gene CG31648 is reported here. It has also been known in FlyBase as CG6922. It encodes a product involved in cytochrome c oxidase biogenesis which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 25E5. There is one recorded allele, which is wild-type. CG31648 is discussed in 7 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0051648
5501 CG31679 CG17006 fruit fly Drosophila melanogaster The D. melanogaster gene CG31679 is reported here. It has also been known in FlyBase as CG17006. It encodes a product with endodeoxyribonuclease activity which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 22D5. There is one recorded allele, which is wild-type. CG31679 is discussed in one reference (excluding sequence accessions), dating from 2002. FB FBgn0051679
5502 CG31682 BcDNA:AT02809;CG17006 fruit fly Drosophila melanogaster The D. melanogaster gene CG31682 is reported here. It has also been known in FlyBase as BcDNA:AT02809 and CG17006. It encodes a product with endodeoxyribonuclease activity putatively involved in nucleobase, nucleoside, nucleotide and nucleic acid metabolism which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 22D5. There is one recorded allele, which is wild-type. CG31682 is discussed in 4 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0051682
5512 CG31741 ;CG5750 fruit fly Drosophila melanogaster The D. melanogaster gene CG31741 is reported here. It has also been known in FlyBase as CG5750. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 36E3. There is one recorded allele, which is wild-type. CG31741 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0051741
5523 CG31802 BcDNA:AT22559;CG15158 fruit fly Drosophila melanogaster The D. melanogaster gene CG31802 is reported here. It has also been known in FlyBase as BcDNA:AT22559 and CG15158. It encodes a product with calcium ion binding putatively involved in calcium-mediated signaling which is a component of the centrosome. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 36F1. There is one recorded allele, which is wild-type. CG31802 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0051802
5536 CG3192 fruit fly Drosophila melanogaster The D. melanogaster gene CG3192 is reported here. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 6C5. There is one recorded allele, which is wild-type. CG3192 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029888
5543 CG3198 fruit fly Drosophila melanogaster The D. melanogaster gene CG3198 is reported here. It encodes a product involved in nuclear mRNA splicing, via spliceosome which is a component of the snRNP U1. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 6C4. There is one recorded allele, which is wild-type. CG3198 is discussed in 3 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0029887
5547 CG3203 anon-EST:Posey276;RpL17 fruit fly Drosophila melanogaster The D. melanogaster gene CG3203 is reported here. It has also been known in FlyBase as anon-EST:Posey276. It encodes a product with structural constituent of ribosome involved in protein biosynthesis which is a component of the cytosolic large ribosomal subunit (sensu Eukarya). It has been sequenced and its amino acid sequence contains a ribosomal protein L22p / L17e. It has been mapped cytologically to 6C10. There is one recorded allele, which is wild-type. CG3203 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0029897
5556 CG32067 anon-WO0118547.361;CG7983;CG8000;l(3)01814;l(3)j4A5;l(3)rN672;p66;simj fruit fly Drosophila melanogaster The D. melanogaster gene CG32067 is reported here. It has also been known in FlyBase as CG7983 and CG8000. It encodes a product with transcriptional repressor activity involved in negative regulation of transcription, DNA-dependent. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 67E6. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG32067 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052067
5557 CG32072 ;CG6261;elo68&agr; fruit fly Drosophila melanogaster The D. melanogaster gene CG32072 is reported here. It has also been known in FlyBase as CG6261. It encodes a product with putative acyltransferase activity (EC:2.3.1.-) involved in very-long-chain fatty acid metabolism which is a component of the endoplasmic reticulum. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 68A6. There is one recorded allele, which is wild-type. CG32072 is discussed in 2 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0052072
5560 CG32089 ;CG7547 fruit fly Drosophila melanogaster The D. melanogaster gene CG32089 is reported here. It has also been known in FlyBase as CG7547. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) putatively involved in cation transport which is a component of the hydrogen-transporting ATPase V0 domain. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 68C9. There is one recorded allele, which is wild-type. CG32089 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0052089
5562 CG32090 ;CG7547 fruit fly Drosophila melanogaster The D. melanogaster gene CG32090 is reported here. It has also been known in FlyBase as CG7547. It encodes a product with hydrogen-exporting ATPase activity, phosphorylative mechanism (EC:3.6.3.6) putatively involved in cation transport which is a component of the hydrogen-transporting ATPase V1 domain. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 68C9. There is one recorded allele, which is wild-type. CG32090 is discussed in 3 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0052090
5566 CG3210 fruit fly Drosophila melanogaster The D. melanogaster gene CG3210 is reported here. It encodes a product with putative small monomeric GTPase activity (EC:3.6.5.2) putatively involved in endocytosis which is a component of the microtubule associated complex. It has been sequenced and its amino acid sequence contains a dynamin central region, a dynamin family and a dynamin GTPase effector domain. It has been mapped cytologically to 23A1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG3210 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031438
5567 CG32103 CG18022;CG4392 fruit fly Drosophila melanogaster The D. melanogaster gene CG32103 is reported here. It has also been known in FlyBase as CG18022 and CG4392. It encodes a product with carrier activity involved in transport which is a component of the peroxisomal membrane. It has been sequenced and its amino acid sequence contains a mitochondrial energy transfer proteins (carrier protein), a EF-hand family, a mitochondrial carrier domain, an adenine nucleotide translocator 1 and a graves disease carrier domain. It has been mapped cytologically to 69B4--5. There is one recorded allele, which is wild-type. CG32103 is discussed in 11 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0052103
5568 CG32105 CG10432;CG17615 fruit fly Drosophila melanogaster The D. melanogaster gene CG32105 is reported here. It has also been known in FlyBase as CG10432 and CG17615. It encodes a product with transcription factor activity involved in regulation of transcription which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 69B1--2. There is one recorded allele, which is wild-type. CG32105 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052105
5570 CG3212 ;CT10789;Sr-CIV fruit fly Drosophila melanogaster The D. melanogaster gene CG3212 is reported here. It encodes a product with scavenger receptor activity involved in defense response which is a component of the integral to plasma membrane. It has been sequenced and its amino acid sequence contains a MAM domain. It has been mapped cytologically to 23F6. There is one recorded allele, which is wild-type. CG3212 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0031547
5573 CG3214 anon-EST:Posey62;BcDNA:GH12382 fruit fly Drosophila melanogaster The D. melanogaster gene CG3214 is reported here. It has also been known in FlyBase as BcDNA:GH12382, anon-EST:Posey62 and anon-ESTPosey62. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 23A1. There is one recorded allele, which is wild-type. CG3214 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031436
5579 CG32174 ;CG3877 fruit fly Drosophila melanogaster The D. melanogaster gene CG32174 is reported here. It has also been known in FlyBase as CG3877. It encodes a product with molecular_function unknown involved in ubiquinone biosynthesis which is a component of the mitochondrial inner membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 74B2--C2. There is one recorded allele, which is wild-type. CG32174 is discussed in 3 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0052174
5585 CG32230 BcDNA:RE56733;BEST:GH04411 fruit fly Drosophila melanogaster The D. melanogaster gene CG32230 is reported here. It has also been known in FlyBase as BcDNA:RE56733. It encodes a product with NADH dehydrogenase activity (EC:1.6.99.3) involved in mitochondrial electron transport, NADH to ubiquinone which is a component of the respiratory chain complex I (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 80E2. There is one recorded allele, which is wild-type. CG32230 is discussed in 5 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0052230
5587 CG3225 fruit fly Drosophila melanogaster The D. melanogaster gene CG3225 is reported here. It encodes a product with ATP dependent RNA helicase activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped cytologically to 25A6--7. There is one recorded allele, which is wild-type. CG3225 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0031631
5588 CG32250 BcDNA:RE36975;CG1326;CG32251 fruit fly Drosophila melanogaster The D. melanogaster gene CG32250 is reported here. It has also been known in FlyBase as BcDNA:RE36975 and CG1326. It encodes a product with transporter activity involved in transport which is a component of the integral to peroxisomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 64B1. There is one recorded allele, which is wild-type. CG32250 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052250
5589 CG32253 CG11583 CG32253 fruit fly Drosophila melanogaster FB FBgn0052253
5590 CG32262 CG10854 fruit fly Drosophila melanogaster The D. melanogaster gene CG32262 is reported here. It has also been known in FlyBase as CG10854. It encodes a product with putative receptor signaling protein activity which is a component of the peroxisomal membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 63F1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. CG32262 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052262
5598 CG32297 CG1247;CG1248 fruit fly Drosophila melanogaster The D. melanogaster gene CG32297 is reported here. It has also been known in FlyBase as CG1247 and CG1248. It encodes a product with RNA cap binding involved in snRNP protein-nucleus import which is a component of the nuclear membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 62E8. There is one recorded allele, which is wild-type. CG32297 is discussed in 4 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052297
5602 CG32316-ORFB CG13918;CG32316;CG33791;CG7934 fruit fly Drosophila melanogaster The D. melanogaster gene CG32316-ORFB is reported here. It has also been known in FlyBase as CG13918 and CG7934. It encodes a product with oxoglutarate dehydrogenase (succinyl-transferring) activity (EC:1.2.4.2) involved in tricarboxylic acid cycle which is a component of the oxoglutarate dehydrogenase complex (sensu Eukarya). It has been sequenced and its amino acid sequence is also available. There is one recorded allele, which is wild-type. CG32316-ORFB is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0035240
5604 CG32343 ;CG6994 fruit fly Drosophila melanogaster The D. melanogaster gene CG32343 is reported here. It has also been known in FlyBase as CG6994. It encodes a product with transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 61C1. There is one recorded allele, which is wild-type. CG32343 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052343
5613 CG32392 CG10099;CG14912 fruit fly Drosophila melanogaster The D. melanogaster gene CG32392 is reported here. It has also been known in FlyBase as CG10099 and CG14912. It encodes a product with putative microtubule binding putatively involved in microtubule-based process which is putatively a component of the microtubule associated complex. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 65C4. There is one recorded allele, which is wild-type. CG32392 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0052392
5614 CG32396 ;CG8339;CT42364 fruit fly Drosophila melanogaster The D. melanogaster gene CG32396 is reported here. It has also been known in FlyBase as CG8339. It encodes a product with structural constituent of cytoskeleton involved in microtubule-based process which is a component of the microtubule. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 65B3--4. There is one recorded allele, which is wild-type. CG32396 is discussed in 6 references (excluding sequence accessions), dated between 2000 and 2003. These include at least one molecular study. FB FBgn0052396
5623 CG32451 anon-WO0118547.249;CG14449;CG7651;SPoCk fruit fly Drosophila melanogaster The D. melanogaster gene CG32451 is reported here. It has also been known in FlyBase as CG14449 and CG7651. It encodes a product with calcium-transporting ATPase activity (EC:3.6.3.8) involved in calcium ion transport. It has been sequenced and its amino acid sequence contains a H+/K+ and Na+/K+ transporting ATPase, a H+-transporting ATPase (proton pump), a haloacid dehalogenase/epoxide hydrolase family and a E1-E2 ATPases. It has been mapped cytologically to 80A1--2. There is one recorded allele, which is wild-type. CG32451 is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2004. These include at least one molecular study. FB FBgn0052451
5624 CG32463 CG17006 fruit fly Drosophila melanogaster The D. melanogaster gene CG32463 is reported here. It has also been known in FlyBase as CG17006. It encodes a product with endodeoxyribonuclease activity putatively involved in DNA replication which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 22D5. There is one recorded allele, which is wild-type. CG32463 is discussed in 3 references (excluding sequence accessions), dated between 2002 and 2003. FB FBgn0052463
5632 CG32528 BcDNA:RE70209;CG12533;CG32530;CG32530-ORFA;CG33931;dRpp20;Rpp20 fruit fly Drosophila melanogaster The D. melanogaster gene CG32528 is reported here. It has also been known in FlyBase as CG12533. It encodes a product with actin binding putatively involved in cell motility. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18E5--F1. There is one recorded allele, which is wild-type. CG32528 is discussed in 6 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0052528
5634 CG32532 CG14201;CG14202;CG14203 fruit fly Drosophila melanogaster The D. melanogaster gene CG32532 is reported here. It has also been known in FlyBase as CG14201, CG14202 and CG14203. It encodes a product with transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus. It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped cytologically to 18C8--D1. There is one recorded allele, which is wild-type. CG32532 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052532
5635 CG32533 CG12211;CG14198 fruit fly Drosophila melanogaster The D. melanogaster gene CG32533 is reported here. It has also been known in FlyBase as CG12211 and CG14198. It encodes a product with ATP dependent RNA helicase activity involved in nuclear mRNA splicing, via spliceosome which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 18C7. There is one recorded allele, which is wild-type. CG32533 is discussed in 10 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0052533
5642 CG32575 BcDNA:GM07804;BcDNA:LD22118;CG4411;CG4416;hang;LD22118 fruit fly Drosophila melanogaster The D. melanogaster gene CG32575 is reported here. It has also been known in FlyBase as BEST:LD22118, BcDNA:GM07804, BcDNA:LD22118, CG4411 and CG4416. It encodes a product with nucleic acid binding. It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 14C4--6. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. CG32575 is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2003. These include at least 2 molecular studies. FB FBgn0026575
5643 CG32604 CG1375;CG1405;EP764;EP784;l(1)G0007;l(1)G0028;l(1)G0103;l(1)G0176;l(1)G0308;l(1)G0416;l(1)G0476;l(1)G0491 CG32604 fruit fly Drosophila melanogaster FB FBgn0052604
5651 CG32649 ;CG32650;CG4410 fruit fly Drosophila melanogaster The D. melanogaster gene CG32649 is reported here. It has also been known in FlyBase as CG4410. It encodes a product with protein kinase activity (EC:2.7.1.37) involved in mitochondrial electron transport, ubiquinol to cytochrome c which is a component of the mitochondrion. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 11D1. There is one recorded allele, which is wild-type. CG32649 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0052649
5653 CG3267 ;FBgn0042083;l(2)4524 fruit fly Drosophila melanogaster The D. melanogaster gene CG3267 is reported here. It encodes a product with methylcrotonoyl-CoA carboxylase activity (EC:6.4.1.4) involved in leucine metabolism which is a component of the mitochondrial matrix. It has been sequenced and its amino acid sequence contains a carboxyl transferase family. It has been mapped cytologically to 42C8. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which are semi-lethal and recessive lethal. CG3267 is discussed in 11 references (excluding sequence accessions), dated between 1994 and 2003. These include at least one molecular study. FB FBgn0042083
5660 CG32701 CG2994 CG32701 fruit fly Drosophila melanogaster FB FBgn0052701
5674 CG32778 ;CG32790;CG4985 fruit fly Drosophila melanogaster The D. melanogaster gene CG32778 is reported here. It has also been known in FlyBase as CG4985. It encodes a product with transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 4A4--5. There is one recorded allele, which is wild-type. CG32778 is discussed in 5 references (excluding sequence accessions), dated between 1999 and 2003. FB FBgn0052778
5675 CG3279 fruit fly Drosophila melanogaster The D. melanogaster gene CG3279 is reported here. It encodes a product with v-SNARE activity putatively involved in intracellular protein transport which is a component of the plasma membrane. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 61C8. There is one recorded allele, which is wild-type. CG3279 is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. FB FBgn0035156
5688 CG3294 fruit fly Drosophila melanogaster The D. melanogaster gene CG3294 is reported here. It encodes a product with pre-mRNA splicing factor activity involved in nuclear mRNA splicing, via spliceosome which is a component of the spliceosome complex. It has been sequenced and its amino acid sequence contains a RNA-binding region RNP-1 (RNA recognition motif). It has been mapped cytologically to 25A6. There is one recorded allele, which is wild-type. CG3294 is discussed in 9 refere