YDL134C
Systematic NameYDL134C
Standard NamePPH21
SynonymPPH1
DescriptionCatalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
CommentNull mutant is viable, pph21 pph22 mutants produce very small spores in some strain backgrounds and are inviable in others, pph21 pph22 pph3 mutants are inviable
Organism
Common Namebaker's yeast
Scientific NameSaccharomyces cerevisiae
Gene Ontology (GO)
Cellular ComponentGO:0000159 protein phosphatase type 2A complex
Molecular FunctionGO:0000158 protein phosphatase type 2A activity
Biological ProcessGO:0000082 G1/S transition of mitotic cell cycle
GO:0006412 protein biosynthesis
GO:0006470 protein amino acid dephosphorylation
GO:0007015 actin filament organization
GO:0007094 mitotic spindle checkpoint
GO:0007117 budding cell bud growth
Localizationgranular staining * granular staining
Sequence
MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDLKPGSSG
IADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQ
FEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRG
YYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSA
NVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVP
HEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARA
HQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYD
PSVRPGEPSVSRKTPDYFL
Length369
Image
 
 
Visualization
Organelle ViewView this protein's localizations in 3D
Data Source
 SGD:S000002292
 Anuj Kumar's lab / Mike Snyder's lab


Kumar Lab
Life Sciences Institute
The University of Michigan.