YDR399W
Systematic NameYDR399W
Standard NameHPT1
SynonymBRA6
HGPRTase
HPRT
Full Namehypoxanthine guanine phosphoribosyltransferase
DescriptionDimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
Organism
Common Namebaker's yeast
Scientific NameSaccharomyces cerevisiae
Gene Ontology (GO)
Cellular ComponentGO:0005634 nucleus
GO:0005737 cytoplasm
Molecular FunctionGO:0004422 hypoxanthine phosphoribosyltransferase activity
Biological ProcessGO:0006164 purine nucleotide biosynthesis
Sequence
MSANDKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPARILRTF
LKEPGVPTIRIFAIILSLYEDLNSVGSEVEEVGVKVSRTQWIDYEQCKLD
LVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKAKGIDTEKSPEMKTN
FGIFVLHDKQKPKKADLPAEMLNDKNRYFAAKTVPDKWYAYPWESTDIVF
HTRMAIEQGNDIFIPEQEHKQ
Length221
Image
 
Visualization
Organelle ViewView this protein's localizations in 3D
Data Source
 SGD:S000002807
 Anuj Kumar's lab / Mike Snyder's lab


Kumar Lab
Life Sciences Institute
The University of Michigan.