YGR167W
Systematic NameYGR167W
Standard NameCLC1
SynonymSCD4
Full Nameclathrin light chain
DescriptionClathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function, two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component
CommentNull mutant is viable but slow-growing and shows defects in receptor-mediated endocytosis, maturation of alpha factor and levels of clathrin heavy chain (Chc1p); high copy suppresses the inviable double mutant chc1-delete, scd1-i-allele; elevated CHC1 expression suppresses some clc1-delete phenotypes
Organism
Common Namebaker's yeast
Scientific NameSaccharomyces cerevisiae
Gene Ontology (GO)
Cellular ComponentGO:0030125 clathrin vesicle coat
Molecular FunctionGO:0005198 structural molecule activity
Biological ProcessGO:0006897 endocytosis
GO:0016192 vesicle-mediated transport
Sequence
MSEKFPPLEDQNIDFTPNDKKDDDTDFLKREAEILGDEFKTEQDDILETE
ASPAKDDDEIRDFEEQFPDINSANGAVSSDQNGSATVSSGNDNGEADDDF
STFEGANQSTESVKEDRSEVVDQWKQRRAVEIHEKDLKDEELKKELQDEA
IKHIDDFYDSYNKKKEQQLEDAAKEAEAFLKKRDEFFGQDNTTWDRALQL
INQDDADIIGGRDRSKLKEILLRLKGNAKAPGA
Length233
Image
 
Visualization
Organelle ViewView this protein's localizations in 3D
Data Source
 SGD:S000003399
 Anuj Kumar's lab / Mike Snyder's lab


Kumar Lab
Life Sciences Institute
The University of Michigan.