YKL149C
Systematic NameYKL149C
Standard NameDBR1
SynonymPRP26
Full NameRNA lariat debranching enzyme
DescriptionRNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition
CommentNull mutant is viable; reduces Ty1 transposition frequency; defective in the process of intron turnover
Organism
Common Namebaker's yeast
Scientific NameSaccharomyces cerevisiae
Gene Ontology (GO)
Cellular ComponentGO:0005634 nucleus
Molecular FunctionGO:0008419 RNA lariat debranching enzyme activity
Biological ProcessGO:0006320 Ty1 element transposition
GO:0006322 Ty3 element transposition
GO:0006401 RNA catabolism
GO:0016074 snoRNA metabolism
Localizationgranular staining of the nucleus and cytoplasm
Sequence
MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSIRDGQDF
KSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGY
VAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKA
NIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPF
FEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKHNKRSHEPP
NKSTSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALD
KCLPRRRWLEILEIEPDTSHASWKDENHRMFWDPEFINNLVICQKNKNLL
SNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDEVRQTKAFI
SKFMT
Length405
Image
 
Visualization
Organelle ViewView this protein's localizations in 3D
Data Source
 SGD:S000001632
 Anuj Kumar's lab / Mike Snyder's lab


Kumar Lab
Life Sciences Institute
The University of Michigan.