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| YMR070W | |||||||
| Systematic Name | YMR070W | ||||||
| Standard Name | MOT3 | ||||||
| Synonym | ROX7 | ||||||
| Full Name | 2 Cys2-His2 zinc fingers at c-terminus, glutamine and asparagine rich | ||||||
| Description | Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes | ||||||
| Comment | Null mutant is viable, displays modest increase in Ty mRNA levels; mot3 deletion can partially suppress mutations in mot1 and spt3. mot3Delta mutants have impaired homotypic vacuole fusion and increased sterol levels. | ||||||
| Organism | |||||||
| Common Name | baker's yeast | ||||||
| Scientific Name | Saccharomyces cerevisiae | ||||||
| Gene Ontology (GO) | |||||||
| Cellular Component | GO:0005634 nucleus | ||||||
| Molecular Function | GO:0003677 DNA binding GO:0016563 transcriptional activator activity GO:0016564 transcriptional repressor activity | ||||||
| Biological Process | GO:0000723 telomere maintenance GO:0006350 transcription | ||||||
| Localization | granular staining; | ||||||
| Sequence | |||||||
| MNADHHLQQQQQQRQQHQQQQHQQQQHQHQHQQQQHTILQNVSNTNNIGS DSLASQPFNTTTVSSNKDDVMVNSGARELPMPLHQQQYIYPYYQYTSNNS NNNNVTAGNNMSASPIVHNNSNNSNNSNISASDYTVANNSTSNNNNNNNN NNNNNNNIHPNQFTAAANMNSNAAAAAYYSFPTANMPIPQQDQQYMFNPA SYISHYYSAVNSNNNGNNAANNGSNNSSHSAPAPAPGPPHHHHHHSNTHN NLNNGGAVNTNNAPQHHPTIITDQFQFQLQQNPSPNLNLNINPAQPLHLP PGWKINTMPQPRPTTAPNHPPAPVPSSNPVASNLVPAPSSDHKYIHQCQF CEKSFKRKSWLKRHLLSHSQQRHFLCPWCLSRQKRKDNLLQHMKLKHTNY LLDELKKNNIIFNYNNSSSSNNNNDNNNNNNSNSASGSGGAGAAAAAATA PENEDGNGYDTNIKTLINDGVLNKDDVKRVLNNLIVSHNK | |||||||
| Length | 490 | ||||||
| Image | |||||||
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| Visualization | |||||||
| Organelle View | View this protein's localizations in 3D| Data Source | | SGD:S000004674 | | Anuj Kumar's lab / Mike Snyder's lab | | |
