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| YPL254W | |||||||
| Systematic Name | YPL254W | ||||||
| Standard Name | HFI1 | ||||||
| Synonym | ADA1 GAN1 SRM12 SUP110 | ||||||
| Full Name | Ada/Gcn5 protein complex member, transcription factor | ||||||
| Description | Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions | ||||||
| Comment | Null mutant phenotypes similar to spt20/ada5 and spt7 mutants. Null mutant is viable, elongated cells, hyperpolarized actin cytoskeleton, heat sensitive, non-respiratory, inositol auxotroph, exhibits suppression of Ty insertion mutations; hfi1 hta1 double mutant is inviable. | ||||||
| Organism | |||||||
| Common Name | baker's yeast | ||||||
| Scientific Name | Saccharomyces cerevisiae | ||||||
| Gene Ontology (GO) | |||||||
| Cellular Component | GO:0000124 SAGA complex GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex GO:0046695 SLIK (SAGA-like) complex | ||||||
| Molecular Function | GO:0003712 transcription cofactor activity GO:0003713 transcription coactivator activity | ||||||
| Biological Process | GO:0006366 transcription from RNA polymerase II promoter GO:0016568 chromatin modification GO:0016573 histone acetylation | ||||||
| Localization | granular staining | ||||||
| Sequence | |||||||
| MSAIQSPAPKPLQPTYPAASPASTNAYMKPGLIGSPAVSNHTEPNNGNNE TAEPQGPNQRIDLGAMIEELTSLLGKESWTKYAQIISLFILGKLSRKELS NELELVFSPSAASLEKSNTNHHHSLVRLHNQLLLGIFANSLRENPLGRNG NESSWGFGNGSNNPNNKLKRINKHNSQIEVYKKIVMSLPLNDRNRLKMIT KEAGKRGFIFCSVFQARLNNIPKIPIVTNPESLKRVKSNNLKTPLEWSQD IMNGFNVPLASESHSLPDTDSFYLRMVGIAREHGLVGTVDARCVELISLA LDQYLKNIIEFTIDTVRYRRKKYSDYYDLNESGLYKSVSEMAADKRDAKI KQLDDDKNEDECADEAKSINNGNNSSKDDIGDISMSSITKAGEAVNEELH ENRTISLTNEDIYDSLSIFPNLVEPSGSYYALTNLGLVNDDELVDMKSNI DDLPDFLNEKPTFTPLDERNVGTRHELNWLIKGILTED | |||||||
| Length | 488 | ||||||
| Image | |||||||
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| Visualization | |||||||
| Organelle View | View this protein's localizations in 3D| Data Source | | SGD:S000006175 | | Anuj Kumar's lab / Mike Snyder's lab | | |
